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Dispensing Exam Three > Transdermal > Flashcards

Flashcards in Transdermal Deck (236):
0

The drug is evenly distributed, can be cut in half, contains a release liner, and is released from the adhesive in which transdermal system

Adhesive matrix

1

Does the nitroglycerin transdermal system relieve acute attacks?

No, nitroglycerin transdermal systems are only indicated for prevention of angina pectoris.

2

What's the trade name for ranolazine?

Ranexa

3

What type of matrix are contained in Minitran and Nitro-Dur?

Adhesive matrix

4

How often is Minitran given?

Qday

5

Which transdermal system can't be cut in half and haas rate controlling membrane?

Reservoir

6

How often should ranolazine (Ranexa) be given?

Bid

7

How often should Nitro-Dur and Minitran be given?

Wear for 12 hours then take off for 12 hours

8

What's the term for painful intercourse?

Dyspareunia

9

What's the term for inflammation of the vagina of thinning and shrinking of tissues?

Atrophic vaginitis

10

What's the BBW for estradiol transdermal systems such as Menostar, Climara, Vivelle-Dot, Alora, and Minivelle?

Increased risk of CVD, dementia, and endometrial cancers

11

Which estradiol transdermal patch is indicated for osteoporosis only?

Menostar

12

Which type of matrix are the estradiol transdermal systems?

Adhesive

13

Which are the strengths for Minivelle?

0.0375, 0.05, 0.075, 0.1 mg/24 hours

14

Which estradiol transdermal comes in a strength of 0.014 mg/24 hours

Menostar

15

How often is Climara given?

Qweek

16

How often are Vivelle Dot and Alora given?

Twice weekly

17

How often is Menostar given?

Qweekly 0.014 mg/24 hours

18

What are the indications for estradiol transdermal systems?

1. Vasomotor symptoms
2. Vaginal atrophy
3. Osteoporosis

19

How often are Minivelle, Alora, and Vivelle-Dot given?

Twice weekly

20

Which estradiol topical emulsion contains soybean oil?

Estrasorb

21

How often is Estrasorb (estradiol) given?

2 packets every morning 0.05 mg/2 packets; place one packet on the leg for 3 minutes, one packet on right leg for 3 minutes, rub the excess on the buttocks

22

What's the trade for estradiol 0.021 mg/spray transdermal spray?

Evamist

23

Where do you spray Evamist?

Spray on the inside of the arm

24

How often should Evamist be given?

One spray daily

25

Which estradiol products are indicated for vasomotor symptoms only?

1. Estrasorb-left and right leg then buttocks
2. Evamist-forearm
3. Divigel-upper thigh

26

How often is Divigel given?

Daily

27

What's the trade for ethinyl estradiol + norelgestromin?

Ortho Evra-given weekly-adhesive matrix-apply 1 patch for 3 weeks then go patch free for one week repeat

28

How often is Activella given?

Qday

29

What are the trade names for estradiol + norethindrone?

CombiPatch, Activella

30

What's the trade name for estradiol and levonorgestrel?

Climara Pro

31

What's the trade for the conjugated equine estrogens?

Premarin Vaginal Creams

32

What's the trade for the 10 mcg vaginal tablet?

Vagifem

33

What's the trade for the 0.1 mg/g vaginal cream?

Estrace

34

What's the maintenance dose for Estrace?

1-3x a week

35

What's the dosing interval for Femring?

0.05 and 0.1 mg/24 hours every three months

36

Which are indicated for VM, VA, and O?

Activella-comes in 0.5 mg/0.1 mg tablet as well as 1 mg/0.5 mg tablet

37

How often is CombiPatch given?

Twice weekly

38

How often is Activella given?

Qday

39

What's the trade for the 0.625 mg/g vaginal cream?

Premarin Vaginal Cream

40

What's the initial dose for Vagifem?

1 tablet qday for 2 weeks then a maintenance dose of 1 tablet twice weekly

41

Which are indicated for VA only?

Vagifem, Premarin Vaginal Cream

42

Which estradiol must be refrigerated?

CombiPatch

43

What are Climara Pro's indication?

Indicated for VM and O

44

What percent is estradiol topical gel?

0.1% in 0.25, 0.5, 1 gram packets of gel

45

What's the dosing interval for Estrace?

Initial: give daily for 2 weeks then after / weeks give half a dose daily daily for 2 weeks
Maintenance: 1-3x weeks

46

Which estradiol products contain alcohol USP?

Evamist, Divigel

47

How much testosterone do men produce daily?

5 mg/day

48

What are the synthetic derivatives of testosterone?

Anabolic steroids

49

What drugs do testosterone transdermal systems interact with?

They decrease anticoagulant and insulin requirements

50

What control level are anabolic steroids?

CIII

51

How often should testosterone transdermals be given?

All are given daily-Androderm, AndroGel, Testim, Fortesta, Axiron

52

What testosterone transdermal patch comes in strengths of 2 mg/24 hours and 4 mg/24 hours?

Androderm

53

Which testosterone transdermal is a reservoir patch?

Androderm

54

Which testosterone transdermal comes in 5 gram single dose packets? 50 mg testosterone= 5 mg absorbed

Testim

55

What single dose packet sizes does AndroGel come in?

2.5 grams, 5 gram= 25 mg, 50 mg testosterone-2.5 mg, 5 mg absorbed via the shoulder

56

What % metered dose pump does AndroGel come in?

1%, 1.62%

57

With a 1% AndroGel testosterone pump, how many milligrams are absorbed via the shoulder?

5 mg absorbed via the shoulder; 1 pump=12.5 mg x 4 pumps= 50 mg with 5 mg absorbed

58

What's the metered dose pump that includes alcohol USP used as a topical solution?

Axiron-give daily-ALL testosterone transdermals are DAILY

59

Which testosterone metered dose pump is applied as two pumps to each thigh to minimize secondary exposure?

Fortesta

60

How often is Kapvay given?

Bid (maintenance)

61

What is. Kapvay indicated for?

ADHD

62

How often is Catapres given?

Qweek it comes in 0.1, 0.2, 0.3 mg/24 hours

63

What is Catapres indicated for?

Hypertension

64

What strengths does Kapvay come in?

0.1 mg, 0.2 mg ER tablet

65

What's the precaution with fentanyl transdermal system?

All may be fatal to children so discard appropriately

66

How often is Duragesic given?

q72h

67

Which fentanyl transdermal is given for chronic pain?

Duragesic-note 12 hour onset

68

What strengths does fentanyl come in?

12.5, 25, 50, 75, 100 mcg/hr

69

How often is Actiq given?

q4h-Rub on side of cheek for 15 minutes

70

What's the trade for the transmucosal lozenge on a stick

Actiq

71

How often is Onsolis given?

q2h

72

How often is the sublingual fentanyl tablet given?

Abstral

73

What's the trade for the fentanyl nasal spray?

Lazanda-1 spray in 1 nostril

74

Which fentanyl product should be placed in a child resistant container?

Lazanda

75

What's the trade for the fentanyl but cal tablet?

Fentora

76

What's the trade for the fentanyl sublingual tablet?

Abstral given q2h

77

How long can a scopolamine patch be left on?

3 days-note: place behind ear for 4 hours

78

If a scopolamine patch is used for surgery, when should it be placed behind the ear?

The evening before surgery

79

What strength does scopolamine come in?

5 mcg/hr

80

What's the trade for scopolamine patch?

Transderm-Scop

81

Which transdermal patch is indicated for pain associated with post herpetic neuropathy?

Lidoderm-lidocaine

82

What's the trade for the 5 % lidocaine transdermal patch?

Lidoderm

83

How often and how long should Lidoderm be applied?

Apply up to 3 patches a day at the same time; put one on for 12 hours, then remove for 12 hours

84

What's the trade for zoster vaccine?

Zostavax

85

What's the trade for varicella vaccine?

Varivax

86

What are the indications for Neurontin?

1. PHN
2. Partial seizures

87

What are the indications for Lyrica?

1. PHN
2. Partial seizures
3. DPN
4. Fibromyalgia

88

What's the trade for mirabegron?

Myrbetriq

89

What's the trade for fesoteridone?

Toviaz

90

What's the trade for solifenacin?

Vesicant

91

What's the trade for darifenacin?

Enablex

92

What's the trade for the ER trospium capsule?

Sanctura XR

93

What's the trade for the IR trospium tablet?

Sanctura

94

How should trospium be taken?

Take on an empty stomach

95

What's the 10% topical oxybutynin gel?

Gelnique

96

What's the trade for the IR oxybutynin tablet?

Ditropan

97

What's the trade for the ER oxybutynin tablet?

Ditropan XL

98

What's the trade for the oxybutynin transdermal 3.9 mg/24 hours adhesive?

Oxytrol

99

How often should Oxytrol be given?

Twice weekly

100

Which class is Myrbetriq a part of?

Beta 3 agonist

101

Where is Gelnique applied?

The abdomen

102

How often is Gelnique given?

Qday

103

How often should Daytrana be given?

Qday

104

What's the indication for methylphenidate and what class?

ADHD; Controlled II

105

What strength does Daytrana come in?

10, 15, 20, 30 mg/9 hours

106

Where do you apply Daytrana and for how long?

Wear on the hip for 2 hours before needed, then take off 9 hours later.

107

What's the trade for granisetron?

Sancuso

108

How often should Sancuso be given?

Qweek-3.1 mg/24 hours

109

What are Zelapar and Eldepryl indicated for?

AntiParkinson's agent

110

What's the generic for Emsam, Eldepryl, and Zelapar?

Selegiline

111

What's the trade for ODT selegiline?

Zelapar

112

What's the indication for Emsam?

MAOI depressant

113

What's a drug interaction with Emsam?

Tyramine 9 mg, 12 mg; avoid pseudoephedrine and phenylephrine

114

What strengths does Emsam come in?

6, 9, 12 mg/24 hours

115

How often should Sancuso be given?

Qweek

116

How often should Emsam given?

Qday

117

What's the trade for aprepitant?

Emend

118

What's the trade for ondansetron?

Zofran

119

What's the trade for dolasetron?

Anzemet

120

What's the trade for palonosetron?

Aloxi

121

Which antiemetic is indicated for N/V patients receiving chemotherapy for 5 straight days?

Sancuso-granisetron

122

How soon should Sancuso be applied to upper arm before treatment?

24 hours and also taken off 24 hours after last treatment

123

What's the trade for galantamine?

Razadyne

124

What's the trade for donepezil?

Aricept

125

What's the trade for Exelon?

rivastigmine?

126

Where should Exelon Patch be applied?

In the middle of the back

127

How often should Exelon Patch be applied?

Qday; it comes in strengths of 4.6,9.5/24 hours

128

What's the dosing interval for Exelon Patch?

4.6 mg x 1 month, then increase to 9.5 mg as maintenance dose

129

How often should Butrans be given?

Weekly

130

What's the trade for parenteral buprenorphine?

Buprenex

131

What's the sublingual buprenorphine tablet?

buprenorphine

132

What's the indication for Buprenex?

Addiction

133

What's the trade for diclofenac epolamine?

Flector Patch

134

How often should Flector Patch be given?

Bid

135

Which COX enzyme does Flector Patch inhibit?

COX-2

136

What are the indications for Flector Patch?

1. Strains-stretched muscle
2. Sprains-stretched ligaments

137

What's a drug interaction with Flector Patch?

Aspirin

138

What's the trade for galantamine?

Razadyne

139

How often should Butrans be given?

Qweek comes in 5, 10, 20 mcg/hour

140

Which strength of buprenorphine are used in opioid tolerant patients?

10 and 20 mcg/hour

141

What's the dosing interval for Exelon Patch?

4.6 mg x 1 month; then increase to 9.5 mg as maintenance dose

142

What category is Zyban?

Aminoketone antidepressant

143

What's the dosing interval for Zyban?

Take 1 tablet for 3 days then bid for 12 weeks

144

How often should Zyban be started before trying to quit?

Give one week to reach therapeutic levels

145

What's the dosing interval for Chantix?

Take 0.5 mg qday for 3 days, then 0.5 mg bid for 4 days, then 1 mg bid for 12 weeks

146

What's Chantix mechanism of action?

Nicotine receptor agonist; varenicline binds to its receptor and produces nicotine-like effects and inhibits nicotine

147

What's the DI for Nicoderm CQ?

Daily

148

What are the strengths of Nicoderm CQ?

7 mg, 14 mg, 21 mg/24 hour adhesive matrix

149

What's the DI for Nicoderm CQ based off of?

Cigarettes smoked per day
>10 cigarettes: 21 mg-6 weeks, 14 mg and 7 mg-2 weeks
<10 cigarettes: 14 mg-6 weeks, 7 mg-2 weeks

150

Where should Nicoderm CQ be applied?

Upper part of arm; remove after 24 hours (do not reuse this site for 7 days) and apply new patch to different site-fold patch in half to discard

151

What's the max daily dose for Nicotrol Inhaler?

Max daily dose/day 16 cartridges= 4 mg cartridge; contains enough nicotine for 20 minutes of active puffing; transmucosal so do. to inhale into lungs

152

Trade for cromolyn sodium?

Nasalcrom

153

Class for Nasalcrom?

Mast Cell Stabilizers

154

Trade for desmopessin acetate?

DDAVP, Stimate

155

Which class is DDAVP and Stimate?

desmopessin acetate

156

Trade for ipratropium bromide?

Atrovent Nasal Spray

157

Which class is Atrovent Nasal spray?

Anticholinergics

158

Which class is Astelin, Astepro?

Antihistamines

159

Which condition are Miacalcin, Fortical indicated for?

calcitonin

160

Which class is Omnaris, Nasonex, Veramyst, Flonase, Rhinocort Aqua, Nasacort AQ?

Corticosteroids

161

What's the trade for triamcinolone?

Nasacort AQ

162

Trade for ciclesonide?

Alvesco

163

Term for rate of diffusion through the skin?

Flux

164

How do you apply a transdermal patch?

Place patch in the middle of the palm and press down on area firmly for 10 seconds to get contact with edges

165

How often should Minitran or Nitro-Dur be given?

Qday or daily

166

Can you take Minitran or Nitro-Dur for an acute attack?

No, it's for prevention of angina pectoris

167

What's the rate of Minitran?

0.1 mg/hr

168

How long do you wear Minitran?

12 hours then give 12 hour break

169

Side effect of Minitran?

Headache

170

How often should Ranexa be given?

Twice daily; comes in 500 mg, 1000 mg strength

171

What category is Ranexa?

Vasodilator

172

Name of the estrogen hormone indicated for hormone replacement therapy in post-menopausal women?

Estradiol

173

Which estradiol transdermal system is indicated for osteoporosis only?

Menostar

174

What BBW do estradiol transdermals have in pre-menopausal women?

Endometrial cancer

175

What BBW do estradiol transdermals have in post-menopausal women?

CVD and dementia

176

Strengths of Climara?

0.025 mg/24 hour
0.0375 mg/24 hour
0.05 mg/24 hour
0.06 mg/24 hour
0.075 mg/24 hour
0.1 mg/24 hour

177

Strengths of Vivelle-Dot?

0.025 mg/hr
0.0375 mg/hr
0.05 mg/hr
0.075 mg/hr
0.1 mg/24 hour

Basically one less than Climara...there's no 0.06 mg/hr

178

Strengths for Alora?

0.025 mg/24 hour
0.05 mg/24 hour
0.075 mg/24 hour
0.1 mg/24 hour

179

Strength of Menostar?

0.014 mg/24 hour

180

When is Estrasorb given?

In the morning

181

When is Evamist given?

Daily or qday

182

What is Estrasorb indicated for?

Vasomotor symptoms only

183

Which estradiol should you not use in allergic to peanuts?

Estrasorb

184

How often should Evamist be given?

Daily

185

What's the indication for Evamist?

Vasomotor symptoms

186

Strength of Evamist?

0.021 mg/spray

187

Indications for CombiPatch?

VM, VA

188

Dosing interval for CombiPatch?

Twice weekly

189

Dosing interval for Climara Pro?

Qweek

190

Indication for Climara Pro?

VM, O

191

Term for a synthetic progesterone?

Progestin

192

CombiPatch should it be kept at room temp or refrigerated?

Refrigerated

193

Max pieces of Nicolette DS?

20

194

Max pieces of Nicorette?

30 pieces

195

Precaution with Nicorette?

Do not swallow

196

How is Nicorette absorbed?

Buccal mucosa

197

The rate and extent of Nicotine is dependent on?

pH dependent

198

What should be avoided when taking Nicorette?

Coffee, soft drinks, fruit juices

199

How many times should you chew Nicorette?

15 times until peppery taste or tingling subsides then place between cheek and gym until taste is gone....repeat for 30 minutes

200

Which nicotine lozenge strength must be taken within 30 minutes of waking?

4 mg

201

Which nicotine lozenge should be taken after 30 minutes of waking?

2 mg

202

What's the dosing interval for nicotine lozenges?

Take 1 lozenge either 2 or 4 mg every 1 to 2 hours for 6 weeks then q2-4 hours for 3 weeks then q4-q8 hours every 3 weeks

203

Nicotrol Inhaler contain nicotine for how many minutes of active puffing?

20 minutes

204

Nicotine lozenge is dose dependent on?

Time to first cigarette

205

What type of system is Nicoderm CQ?

Adhesive matrix transdermal system

206

Where should Nicoderm CQ be applied?

Apply daily to clean, hairless, dry area on upper outer part of arm

207

Is a person smokes less than 20 cigarettes a day, what's the DI?

14 mg for 6 weeks
7 mg for 2 weeks

208

Is a person smokes more than 20 cigarettes a day, what's the DI?

21 mg for 6 weeks, 14 mg for 2 weeks, 7 mg for 2 weeks

209

Category for Lidoderm?

Local anesthetics

210

Does Lidoderm contain percutaneous absorption enhancer?

No; don't want it to go into systemic circulation

211

Lidoderm treats?

Pain from PHN, herpes zoster, varicella virus

212

What age group is Zostavax indicated for?

Patients 50 and older

213

How often should Oxytrol be taken?

Twice weekly comes in 3.9 mg/24 adhesive matrix

214

What's the TC for Oxytrol?

Antispasmodic or Anticholinergic

215

How often should Gelnique be given?

Daily

216

How should Sanctura and Sanctura XR be taken?

On an empty stomach

217

How often should Emsam be given?

Daily

218

What's the category for Emsam?

MAOI antidepressant

219

What's the trade of the only transdermal patch indicated for depression?

Emsam

220

Trade for selegiline capsule?

Eldepryl

221

Trade for selegiline ODT?

Zelapar

222

What's the trade for selegiline capsule?

Eldepryl

223

What are Eldepryl and Zelapar indicated for?

AntiParkinson's

224

What adhesive matrix strengths does Ensam come in?

6 mg/24 hr, 9 mg/24 hr, 12 mg/24 hr

225

What's the category for Emsam?

MAOI antidepressants

226

Patient counseling for Sancuso?

Avoid photo toxic reaction by avoiding sun to area patch was applied for 10 days following removal.

227

How often should Exelon Patch be given?

Daily

228

What's the strength for Exelon patch?

4.6 mg/24 hr; 9.5 mg/24 hr

229

What's the category for Exelon patch?

Cholinesterase inhibitors

230

How does Exelon Patch work?

Increases Acetylcholine levels

231

What dose do patients start on with Exelon patch?

4.6 mg initial for a thought then a maintenance of 9.5 mg per dose

232

Where should Exelon Patch be applied?

Middle of the back

233

What's the category for Razadyne and Aricept?

Cholinesterase inhibitors

234

What's the category for Butrans?

Opioid analgesics give it weekly do not reuse same site for 3 weeks

235

Trade for buprenorphine adhesive matrix?

Butrans in strengths of 5 mcg/hr, 10 mcg/hr, 20 mcg/hr