Transmission Flashcards
(5 cards)
Neurons
- building blocks of the CNS
- receives, process and transmits information throughout the body
- 86 billion in the human brain
- cognition, sensory processing and motor control
Neurotransmitters
chemical messengers that transmit signals between neurons to other neurons across a synaptic cleft
- dopamine
- noradrenalin
- serotonin
- acetylcholine
drugs and synaptic transmission
+ = agonist - binding to receptor and activating mimicking neurotransmitter
- = antagonist - bind and not activate, blocking the neurotransmitter
neurochemicals in addiction
Gerra et al
PRL - prolactin
fenfluramine promotes 5-HT release
evidence of psychology (stress)
Miczek and Mutchsler
- rats trained to respond to cocaine or food reward
- social stress - 60 mins intruder in cage of resident rat
- selective effect of social stress on cocaine - reinforcing responding
- clinical reports = role of stressful life events in relapse BUT… correlational