trauma and psychosis Flashcards
(8 cards)
What are the global statistics regarding psychosis?
Over 20 million people are affected globally, and people with psychosis die approximately 20 years earlier than the general population
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What are the key symptoms of schizophrenia disorders according to ICD/DSM?
Key symptoms include:
Thought interference
Thought sonorisation (hearing thoughts spoken aloud)
Third-person hallucinatory voices
Passivity experiences
Thought disorder
Negative symptoms (blunted affect, anhedonia)
What is the clinical triad of paranoid schizophrenia?
Paranoia - Feeling threatened; belief others intend harm
2. Delusions - Strong beliefs maintained despite contrary evidence
3. Hallucinations - Sensory perceptions without external stimuli
How is developmental trauma defined?
Trauma during childhood/adolescence, including all forms of abuse, particularly when inflicted by primary caregivers
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What are the outcomes of developmental trauma in psychosis?
More severe psychotic illness
Poorer treatment response
Higher hospital re-admission rates
Weaker engagement with services
Population Attributable Risk (PAR) of ~30% for psychosis
What brain areas are affected by developmental trauma?
Threat Processing: Altered amygdala response
Emotion Regulation: ACC hyperactivation
Reward Processing: Blunted striatal response
Executive Function: ACC hyperactivation
How does developmental trauma affect clinical presentation in psychosis?
patients show:
More severe symptoms
Hallucination content linked to traumatic memories
Voices echoing trauma experiences
Perpetrator-related voices
Negative schematic content
Greater fear response to voices
What are the key mechanisms linking trauma to psychosis?
Neurobiological Changes:
Altered dopamine system development that persists into adulthood
Structural brain changes including reduced cortical thickness and decreased hippocampal volume
Psychological Impact:
Disrupted predictive coding leading to delusional beliefs and hallucinations
Impaired threat and emotion processing
Affected reward processing
Clinical Manifestations:
More severe symptoms
Hallucinations often connected to trauma experiences
Higher fear response to voices
