unfamiliar Brand and generic

Question 1

Airsupra

Answer 1

albuterol and budesonide

• first “dual-action” rescue inhaler for asthma

Question 2

symbicort

Answer 2

budesonide and formoterol

• formoterol - works within 5 minutes, but last 12 hours
• • albuterol - works in 5 minutes, but LAST ONLY 6 HOURS

Question 3

dulera

Answer 3

mometasone and formoterol

Question 4

asmanex

Answer 4

mometasone

Question 5

truvada

Answer 5

emtricitabine and tenofovir DISOPROXIL FUMARATE

• go to for “PrEP” –> pre-exposure prophylaxis medication HIV
• avoid in CrCl < 60 ml/min

Question 6

Descovy

Answer 6

emtricitabine and tenofovir ALAFENAMIDE
* see salt different between truvada and descovy

• avoid in crcl < 30 ml/min - (truvada < 60 ml/min)

Question 7

Apretude

Answer 7

Cabotegravir

• PrEP –> pre-exposure prophylaxis med HIV
• gluteal injection given by healthcare provider

Question 8

Exxua side effects

Answer 8

dizziness, nausea, headache

• QT prolongation - more than citalopram

Question 8

Exxua

Answer 8

Gepirone ER

• depression
• first selective serotonin 1A receptor agonist
• think of it similar to buspirone

Question 9

treatment of patient with minor stroke and duration

Answer 9

DAPT - dual anti platelet therapy

• ASA + clopidogrel QD x 21 days
• 10 days for patient high risk for bleeding
• Start within 72 hours of stroke
• after 21 days - continue 1 anti platelet (ASA) QD indefinitely (long-term)

Question 10

can you store benzoyl peroxide product in frig?

Answer 10

Yes

• slow benzene formation
• benzene is a carcinogen - more production especially in high heat

Question 11

what is retinoid?

Answer 11

a vitamin A - increase cell turnover (acne tx)

Question 12

name 2 retinoids use in acne tx?

Answer 12

1. adapalene 0.1%
2. Tretinoin

vitamin A products

Question 13

retinoids (adapalene and tretinoin) can cause

Answer 13

photosensitivity - use sunscreen

Question 14

Winlevi

• generic name

Answer 14

clascoterone

• androgen receptor inhibitor - for acne

Question 15

can you use Clindamycin PO and doxy PO alone in treatment of acne

Answer 15

don’t recommend alone

needs to be use with benzoyl peroxide to limit resistance

Question 16

what is the Pomodoro technique

Answer 16

25 minutes work (focus) follow by 5 minute breaks

Question 17

Omalizumab (Xolair) is for food allergy ..if you inject omalizumab, can you eat anything you want?

Answer 17

No. It is to prevent allergic reaction for ACCIDENTAL exposure only

it doesn’t allow a patient to eat freely whatever they want

Question 18

tx: swollen breast or mastitis due to breast feeding

Answer 18

apply ice and take ibuprofen PRN

• do not recommend HEAT or massage - may worsen symptoms

Question 19

herbal remedies for lactation

Answer 19

fenugreek, milk thistle

do not recommend due to no evidence that it works

Question 20

LTBI stands for

Answer 20

latent tuberculosis infection

Question 21

tx for LTBI

Answer 21

1. rifampin QD x 4 months
2. INH + rifapentine (Priftin) Weekly for 12 doses (84 days)
3. INH QD for 6 to 9 months
4. Rifapentine QD x 3 months

Question 22

is rifampin and rifapentine interchangeable?

Answer 22

No.

Rifapentine is an alternative if rifampin is not available

Question 23

Normally, rifampin base therapy is prefer in LBTI over INH, when is INH preferred?

Answer 23

drug intxn with HIV treatment (rifampin - inducer)

Question 24

patient is taking INH, what supplement is recommended

Answer 24

Vit B6 25 mg to 50 mg QD * to prevent peripheral neuropathy

Question 25

what is berberine use for?

Answer 25

weight loss * increases GLP-1 secretion - called "nature's ozempic" * many drug interaction

Question 26

active treatment of TB has 2 phases how many drugs and how long is each phase

Answer 26

total usually 6 months 2 months (intensive) = RIPE therapy * 4 drugs 4 months (continuation) = 1 to 2 drugs

Question 27

RIPE tb treatment

Answer 27

R = Rifampin I = isoniazid P = pyrazinomide E = Ethambutol

Question 28

Rifampin (active TB) dose

Answer 28

10 mg/kg PO daily (max: 600 mg) * or BIW - TIW

Question 28

contraindication to Rifampin

Answer 28

Protease inhibitor * rifampin - do not use with protease inhibitor (HIV treatment)

Question 29

Rifampin SE (2)

Answer 29

Increased LFT Orange-red discoloration

Question 30

how to take rifampin

Answer 30

empty stomach

Question 31

Isoniazid (active TB) dose

Answer 31

5 mg/kg PO daily (max 300 mg) * can be give once, twice or 3 times a week

Question 32

how to take isoniazid

Answer 32

empty stomach

Question 33

isoniazid contraindication

Answer 33

liver disease ACTIVE * increase LFT

Question 34

what supplement is recommended to patient on isoniazid

Answer 34

vitamin b6 25 mg daily * prevent neuropathy

Question 35

isoniazid SE (2)

Answer 35

increase LFT DILE - drug induced lupus * isoniazid is a DILE drug

Question 36

Pyrazinamide active TB dose

Answer 36

25 mg/kg per daily * dose ONCE daily (in active TB) * not once, twice or 3 times a week * other TB meds can be dose once or twice or 3 times a week

Question 37

contraindication to pyrazinamide (2)

Answer 37

acute gout - can increase uric acid Liver disease (active)

Question 38

pyrazinamide side effects (2)

Answer 38

increase LFT increase uric acid - gout flare

Question 39

Ethambutol active TB dose

Answer 39

20 mg/kg daily 30 mg/kg TIW 50 mg/kg BIW * can be dose once daily, BIW or TIW

Question 40

contraindication to ethambutol

Answer 40

E = ethambutol = eye * optic neuritis (inflammation of optic nerves) * can lead to pain, loss of vision

Question 41

Ethambutol SE (3)

Answer 41

increase LFT Optic neuritis (inflammation of optic nerves = pain, loss of vision) CNS: confusion, hallucination

Question 42

Latent TB treatment * 4 options

Answer 42

INH + rifapentine: QWK for 12 dose INH + Rifampin: QD for 3 months Rifampin: 600 mg QD for 4 months INH: 300 mg QD for 6 to 9 months * preferred in HIV patient (less intxn)

Question 43

Cipro dosing

Answer 43

adjust for renal function