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Flashcards in Unit 1 Deck (88)
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1

The neutrophil count increases during the inflammatory process, especially with _______ infections

bacterial

2

Leukocytosis is elevated especially with _____ and _____

bacterial infections and tissue injury

3

Immature forms of neutrophils are called ______, because of the horseshoe shape of their nuclei

bands

4

Largest of the circulating leukocytes

macrophages

5

Arrive at inflammatory site shortly after the neutrophils and perform their phagocytic functions for several days

monocytes/macrophages

6

Important in inflammation associated with immediate hypersensitivity reactions and allergic disorders

eosinophils, basophils and mast cells

7

Bind to immunoglobulin E (IgE), triggoring the release of histamine and vasoactive agents from the basophil granules

Basophils and mast cells

8

Circulate in the blood and are recruited to tissues, similar to neutrophils. Increase during allergic reactions and parasitic infections.

Eosinophils

9

Secretes histamine (type of WBC)

Mast cells

10

Causes dilation of arterioles and increases permeability of venules, acts at the level of microcirculation by binding to (H1) receptors on endothelial cells

Histamine

11

Promote platelet aggregation and vasoconstriction (inflammatory mediator)

Prostaglandins (ASA/NSAIDS block prostaglandin synthesis, helping reduce inflammation)

12

Inflammatory mediator that effects permeability of postcapillary venules, adhesion properties of endothelial cells, and extravasation/chemotaxis of neutrophils, eosinophils and monocytes- slow reacting substance of anaphylaxis

Leukotrienes (LT)

13

TNF-(alpha) and IL-1 are examples of two major _____

cytokines

14

Features of the release/stimulation of this protein include systemic responses like fever, hypotension, tachycardia, anorexia, release of neutrophils into circulatin and increased levels of corticosteroid hormones

Cytokines

15

Acute inflammatory reactions are characterized by ______ and ______

vascular changes and leukocyte infiltration

16

3 phases of wound healing

inflammatory, proliferative and wound contraction/remodeling

17

transmis infection by self-propagation, no genetic material present

prions

18

smallest obligate intracellular pathogens with no organized cellular structures

viruses

19

incapable of replicating outside of a living cell

virus

20

autonomously replicating unicellular organisms- prokaryotes- lacking an organized nucleus

bacteria

21

spherical bacteria

cocci

22

bacteria with cell wall composed of peptidoglycan

gram positive

23

bacteria with outer membrane composed of lipopolysaccharide

gram negative

24

cocci in chains

streptococci

25

cocci in pairs

diplococci

26

cocci in clusters

staphylococci

27

Cells that are the bridge between the innate and adaptive immune systems

Dendritic Cells (DCs)

28

Cell membrane contains different types of protein and carbohydrate molecules embedded in a semipermeable phospholipid bilayer

Fluid Mosaic Model

29

diffusion and osmosis

passive transport

30

process by which substances become widely dispersed and reach a uniform concentration because of the energy from their spontaneous kinetic movements

diffusion