Unit 2: 2 - Osteoarthritis Flashcards
(44 cards)
What is a diarthrodial joint?
Joint where 2 bones come together
What does poor joint lubrication result in?
Increased friction
What is synovial fluid?
A dialysate of blood
What are 2 functions of synovial fluid?
- Lubrication
- Nutrition to the articular cartilage
What is the chief glycosaminoglycan (GAG)?
Hyaluronic acid (HA)
What are 3 features of HA?
- High molecular weight
- Prevents dilution
- Provides viscosity
What can occur if HA is low in quality and quantity?
Osteoarthritis
How much of articular cartilage is made up of water?
70-80%
What is the green arrow pointing to?
Hyaluronic acid backbone of articular cartilage
What is contained in the blue oval?
Proteoglycan complex
OA is aberrant _____ and _____ of articular cartilage.
repair, degradation
OA consists of bone formation called _____ at the _____ margins.
osteophytosis, synovial
OA results in ___articular fibrosis.
peri
The vast majority of OA in dogs is _____ OA.
secondary
T/F: There is NO cure for OA
True
What happens once OA starts?
it will progress
Do radiographic signs for OA correlate with clinical function?
No
What should you treat with secondary OA?
The primary cause
What should be decreased when there is secodary OA?
The inflammatory response
What should we do regarding cartilage in secondary OA?
Maintain cartilage health
What are 4 ways to medically manage OA?
- Weight management
- Exercise moderation
- Chondroprotectives
- Pain management
What are 2 things that we can do to moderate exercise in a pet with OA?
- Controlled exercise
- Low-impact (leash-walking, swimming)
What are 6 chondroprotectives we can use in OA?
- Glucosamine
- Chondroitin sulfate
- Manganese ascorbate
- Avocado/soybean unsaponifiables (ASU)
- MSM
- Omega 3 fatty acids
How long should chondroprotectives be given?
Give for 6 weeks and continue if working
