Unit 4 Flashcards
(42 cards)
What are the different types of Cell Communications? (4)
- Direct cell-cell communications
- Paracrine
- Endocrine
- Autocrine
How does direct cell-cell communication work?
A cell touches another cell, the protein link
the gap is called
animal = gap junction
plant = plasmodesmata
Paracrine?
Short Distance communication
Synaptic = use of neurons
Endocrine?
Long distance communications
Autocrine
Receptor bind to its own Ligand
What are the three types of membrane CELL SURFACE receptors?
- Ligand - gated ion channels
- G-protein coupled receptors
- Enzyme linked receptors
Ligand gated ion channels
The receptor binds to the ligand, opening up a ion channel
Enzyme linked receptors
An enzyme binds to its substrate, setting off a chain of reactions in the cell
G-Protein
Review chart
Primary Messenger
A ligand that binds to a receptor on the outside of the cell, setting off a chain of reactions
Secondary Messenger
the ligand that is set off by the primary messenger, making the game of telephone happen
Gain of Function
A mutation in the cell which makes the reaction occur without the receptor binding to the ligand
Loss of Function
A mutation in the cell which makes the reaction NOT occur even when the receptor binds to the ligand
Homeostatis
Tendency to go to stable internal enviorment
Positive Feedback Loop
Amplifies stimulus
Negative Feedback Loop (4 parts)
Stimulus - thing happens
sensor - thing is noticed
control - reduce that thing
effector - back to normal
Set Point
The stable target value
Stimulus
Trigger for feedback / “cue”
decondensed
“stringy”
condensed
not stringy, compact
What’s wrong with cancer cells? (4)
- Constantly reproduce cells
- Cells have damaged DNA
- They don’t die
- They spread
autosomes
Non-sex chromosomes
signal relay pathway
game of telephone with ligand and receptors
what do we mean by ligand is turned on?
Phosphorylation - ADP is converted to ATP with the help of enzyme Kinase