Unit I - Infectious Diseases Flashcards

(48 cards)

1
Q

s/s of infectious disease

A
fever
chills
malaise
enlarged lymph nodes
arthralgia, myalgia
headaches, nausea, vomiting, diarrhea
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2
Q

cause of infectious diseases - pathogens

A

bacteria
viruses
parasites
fungi

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3
Q

normal body temperature

A

98.6 deg F (oral)
37 deg C
*add 1 degree for axillary measurement
*subtract 1 degree for rectal measurement

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4
Q

fever

A

fever <102 benign; >102 is emergency

fever of unknown origin (FUO)

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5
Q

before an infection can occur, there must be a

A

reservoir (other person, food, water, soil, animal, insects)

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6
Q

portal of exit from the reservoir

A

routes:

  • genitourinary
  • GI route
  • respiratory
  • open wound: skin
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7
Q

vector: mode of transmission for exit into the recipient

A
  • contact (skin to skin, mucous membrane)
  • airborne (droplets or particles)
  • oropharyngeal (contaminated food/water)
  • moving vector (insects, animals)
  • sexual contact
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8
Q

portal of entry

A

mouth, nose, skin

reservoir: infection lives in the recipient

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9
Q

pathogens

A

organisms that cause infectious diseases

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10
Q

bacteria

A

microscopic and 1 cell

reproduce at a rapid rate

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11
Q

virus

A

ultramicroscopic infectious agent

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12
Q

parasite

A

organism that lives in someone and takes its nourishment from them; cannot live independently

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13
Q

bacterial infections - gram stain

A

positive stains purple

negative stains pink

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14
Q

Staphylococcal infections (Gram +)

A

Pathogen residing in the skin, spread by direct contact
Penetration into deep layers of skin via har follicle can cause abscess and suppurative drainage
Folliculitis—infection of hair follicle
Septic arthritis—joint infection
Infective endocarditis—heart valve infection
Osteomyelitis—bone marrow infection

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15
Q

MRSA: Methicillin Resistance Staphylococcus Aureus

A

Powerful staph infection that is resistant to many antibiotic medications
Colonization—bacteria living on skin or in nose
Healthy person can carry Staph bacteria and infect others

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16
Q

MRSA at risk and symptoms

A

At risk populations:
Post-op, Diabetics, HIV, Kidney failure, lung infection, burns, IV drug users

Symptoms:
Sepsis, palpitations, dysrhythmias
Sepsis with shock
Organ failure 
Can cause necrotizing fasciitis
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17
Q

Streptococcus Pyogenes (group A)

A
  • Present in nasal cavity and pharynx
  • Overgrowth and aggregation—causes problem
  • Streptococcal pharyngitis (strep throat): Red or white tonsils; White because WBC come in to fight it off and are killed off in large numbers
  • Impetigo
  • Causes lesion on the face—superficial so generally heals up with little scarring
  • Transmission can be airborne or by direct contact
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18
Q

Streptococcus Pyogenes Rheumatic Fever with Febrile Illness (CANCER)

A
C: Carditis (infective endocarditis)
A: Arthritis
N: Nodules (subcutaneous lymph nodes) 
C: Chorea—Choreiform Movements 
Generally not permanent 
Continuous movement all over body 
ER: Erythema Marginatum 
Pink raised non-itchy rash
Affects extensor surfaces (back of forearms, arms, trunk)
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19
Q

S. Pneumoniae (pneumococcus)—Group A

A

Most common cause of bacterial pneumonia and bacterial meningitis in children and adults

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20
Q

other bacterial infections s. pyogenes

A

Streptococcal Gangrene

Streptococcal Necrotizing Fasciitis/Myositis (“flesh-eating”)

21
Q

Choreiform movements

A

ceaseless occurrence of rapid, highly complex jerky movements that appear to be well coordinated but are performed involuntarily.

Sydenham’s Chorea

22
Q

S. Pneumoniae (Pneumococcus)-

A

Bacterial Pneumonia
Bacterial Meningitis

compresses brain causing brain damage
Common in teenagers

23
Q

S. Agalactiae (Group B strep)-Baby strep

A

Found in Vaginal Secretions and GI Tract
Neonatal Pneumonia
Neonatal Meningitis
Neonatal Sepsis with Neonatal Toxic Shock Syndrome

24
Q

gangrene (gram +)

A

dead tissue because of ISCHEMIA

results in sepsis if goes on for long enough (septicemia)
infection becomes blood born with inflammation, hypotension, bleeding, hypothermia, organ failure, death

25
most common forms of gangrene!!
C. perfingens, C. fusiformis, C. putrificans
26
dry gangrene
ischemia with a line of demarcation - not getting circulation there - darkened tissue
27
wet gangrene
moist, progressive
28
gas gangrene
edema, gas pockets, foul odor | infected with clostridium
29
necrotizing fascitis
can cause gangrene | - staph, strep
30
cellulitis
diffuse broad area of inflammation of dermis/epidermis | - will mark with a sharpie to see progress
31
outcomes of gangrene
``` • Healing –Hyperbaric O2 • Penicillin and clindamycin • Amputation • General sepsis -Febrile (high body temperature) -Hypotension with organ failure ```
32
bacterial - Pseudomonas Aeruginosa | Gram -
Opportunistic, common nosocomial (hospitals) disease: - Skin/wound infections - UTIs - Osteomyelitis - Pneumonia - If disseminated, cause Sepsis
33
example of Pseudomonas Aeruginosa
Ecthyma gangrenosum—red halo around skin breakdown grows in Whirlpool tanks, Respiratory equipment, Liquid soap dispensers Releases strong, necrotizing enzymes **Responsible for green-pigmented discharge in suppurative infections Sites of infection CNS, skin, bones and joints another example: Osteomyelitis-Infection in the 4th Metatarsal Head
34
Identify and discuss the most common viral infection
``` Rhinovirus Hepatitis Herpes viruses (8) Influenza virus Mononucleosis Cytomegalovirus Respiratory syncytial virus HIV ```
35
rhinovirus
most common virus in humans (99 strains), and a causative agent of upper respiratory infections (i.e. a cold). Primary portal of entry for rhinoviruses is the upper respiratory tract. Virus binds to respiratory epithelial cells. Infected cells release distress signals in the form of pro-inflammatory cytokines-activate inflammatory response
36
herpes simplex-1
- transmitted by direct contact - oral herpes (cold sores) - infection is lifelong - complications: encephalitis, meningitis, retinitis
37
herpes simplex-2
STD - genital herpes transmitted by direct sexual contact - infection is lifelong, not self limiting - complications: encephalitis, meningitis, retinitis
38
Varicella (herpes) Zoster Virus
- causes varicella (chicken pox) - respiratory droplets, diet contact with varicella blisters - 10 day incubation period - 1-2 weeks self limited course - causes shingles
39
post-herpetic neuralgia
- affects 10-20% of patients that have had shingles
40
herpes virus 4
- epstein barr virus - 4-6 week incubation period - Self-limiting course 4-8 weeks - Mode of transmission through saliva - s/s: febrile and extreme fatigue, spleen and liver enlargement, pharyngitis
41
epstein barr - maculopapillary rash and diagnosis
Macules are flat, discolored spots Papules are small, raised bumps Dx: monospot test
42
herpes - human cytomegalovirus
Direct contact with: Blood, Saliva, Tears, Breast milk, STD ~80% are infected Virus is dormant in healthy people Cytomegalic inclusion body disease (CIBD) Usually asymptomatic problematic: pregnancy
43
congenital viral infections - TORCH
``` T=Toxoplasmosis O=Other (HIV) R=Rubella C=Cytomegalovirus H=Herpes Simplex II ```
44
HHV-6 and HHV-7
``` Both are Common Infections Both Cause Roseola Transmission: Respiratory droplets Saliva Fever (3-5 days) Rash (Several days) ```
45
HHV-8
Kaposi’s Sarcoma-AIDS - cutaneous lesions, brown spot of neck or face - metastatic quality cancer
46
respiratory viruses - seasonal influenza virus (details of strains)
- 3 strains (A, B, C) All 3 strains affect humans (B and C only in humans) Some A strains may infect across species All 3 strains are very contagious & cause flu epidemics Transmission: Direct contact and/or Airborne route (Respiratory Droplets)
47
influenza virus complications
- viral pneumonia | - sinusitis and maxillary sinus infection
48
para-influenza virus
respiratory syncytial virus - direct contact or respiratory droplets - mostly children - may cause bronchiolitis