Urology Flashcards
(64 cards)
What is Hydronephrosis?
Swollen kidney
What causes Hydronephrosis?
Obstruction of urine flow from the kidney at the ureteropelvic junction
What are common causes of obstruction in Hydronephrosis?
Kidney stones
Prostate Hyperpasia
Cervical cancer
Retroperitoneal Fibrosis
Congenital Malformation: bladder obstruction
Ureter injury during surgery
What is the best test for Hydronephrosis?
US: showing dilation of the renal pelvis and upper ureter
How do you treat Hydronephrosis?
relief of obstruction
Percutaneous Nephrostomy tube
Observe for post-obstructive diuresis and correct electrolytes PRN
What is Urge Incontinence?
Involuntary leakage of urine with significant urgency: sudden and compelling desire to pass urine immediately
What is stress incontinence?
Involuntary leakage with exertion, sneezing and/or coughing
What is mixed incontinence?
Involuntary leakage associated with both urgency and stress
What is postvoid dribbling?
Slow escape of urine retained in the urethra after the bladder has emptied
What is the best initial therapy for incontinence?
Lifestyle modification
-Weight loss, dietary changes
-bladder training
-pelvic floor muscle exercises
What drug classes are commonly used for Urge incontinence?
Antimuscarinic drugs and beta-adrenergic agonists
What drug class is used for urge incontinence with BPH?
alpha-blockers
What drug is used for non-responsive stress incontinence?
Duloxetine
What is BPH?
noncancerous increase in prostate size
What common symptoms are associated with BPH?
Storage: increased daytime frequency, nocturia, urgency
Voiding: slow stream, splitting or spraying, intermittent stream, hesitancy, straining, terminal dribbling
What is the best initial treatment for BPH?
Alpha-1 antagonists
What are common alpha-1 antagonist drugs?
Tamsulosin, Terazosin, Dozazosin
What is the most common side effect of alpha-1 antagonists?
Hypotension
What other drug class is used for BPH?
5-alpha-reductase inhibitors: reduce the size of the prostate over 6-12 months
What are common 5-alpha-reductase inhibitor drugs?
Finasteride and Dutasteride
What are common risk factors for Erectile Dysfunction?
Obesity, diabetes and depression
What is the first class of drugs used for Erectile Dyfunction?
PDE-5 inhibitors
What are common PDE-5 Inhibitors?
Sildenafil, Vardenafil, Tadalafil, Avanafil
What patients are PDE-5 inhibitors contraindicated in?
Patients taking Nitrates
Caution in alpha-blockers