USMLE VIROLOGY-3

Question 1

Questions

Answer 1

Answers

Question 2

DNA viruses

Answer 2

HHAPPPy viruses!

Herpes
Hepadna
Adeno
Papova
Parvo
Pox

Question 3

adenovirus basics

Answer 3

linear dsDNA

naked

Question 4

adenovirus transmission

Answer 4

resp, ocular secretions

Question 5

adenovirus sx

Answer 5

acute resp dz (ARD)
conjunctivitis
gastroenteritis

Question 6

adenovirus vaccine

Answer 6

live nonattentuated
oral
used in military

Question 7

papovaviruses include

Answer 7

HPV
BK
JC

PA/PO/VAviruses are all abbreviated!

Question 8

JC virus causes

Answer 8

PML (progressive multifocal leukoencephalopathy)

esp in AIDS pts

Question 9

herpesvirus basics

Answer 9

large dsDNA virus

enveloped

Question 10

VZV transmission

Answer 10

resp secretions

Question 11

chickenpox incubation

Answer 11

2w

Question 12

varicella vaccine

Answer 12

live attenuated

Question 13

EBV transmission

Answer 13

saliva, resp secretions

Question 14

EBV associations

Answer 14

burkitt lymphoma
nasopharyngeal carcinoma
hairy oral leukoplakia (immunocompromised)

Question 15

oncogene in burkitt lymphoma

Answer 15

c-myc

Question 16

EBV cells on peripheral smear

Answer 16

atypical lymphocytes = activated T cells

foamy cytoplasm (Downy cells)

Question 17

Paul-Bunnell test

Answer 17

monospot

Question 18

blueberry muffin baby

Answer 18

deaf baby with hemorrhagic cutaneous lesions

congenital CMV

Question 19

HHV-6

Answer 19

causes “sixth disease” = roseola = exanthema subitum

Question 20

HHV-8

Answer 20

cofactor in Kaposi sarcoma

Question 21

poxviruses include

Answer 21

variola (smallpox)
molluscum contagiosum
cowpox

Question 22

umbilicated wart-like lesions

Answer 22

molluscum

Question 23

hepadnaviruses include

Answer 23

hepatitis B virus

Question 24

parvovirus (B19) basics

Answer 24

small ssDNA virus

Question 25

parvovirus causes

Answer 25

erythema infectiosum (fifth dz) aplastic crisis hydrops fetalis

Question 26

picornavirus basics

Answer 26

(+)ssRNA | naked

Question 27

picornaviruses include

Answer 27

PERCH on a "peak" (pico) ``` Polio ECHO Rhino Coxsackie Hepatitis ```

Question 28

poliovirus vaccine(s)

Answer 28

``` live attenuated (oral) killed ```

Question 29

ECHO viruses

Answer 29

Enteric Cytopathic Human Orphan infect GI tract, esp. in summer aseptic meningitis, fever, rash, enteritis, common cold, hemorrhagic conjunctivitis

Question 30

coxsackie season

Answer 30

summer + fall

Question 31

coxsackie transmission

Answer 31

nasopharyngeal secretions | also fecal-oral

Question 32

hepatitis A caused by

Answer 32

enterovirus 72 (picornavirus)

Question 33

herpangina

Answer 33

coxsackie A

Question 34

hand-foot-and-mouth dz

Answer 34

coxsackie A