1. Where do DNA viruses replication 2. Exception

1. nucleus 2. poxvirus (carries its own DNA-dependent RNA pol)

1. Where do RNA viruses replication 2. exception

1. cytoplasm 2. influenza, retrovirus

USMLE Micro virology Flashcards by neurodome zzzz

Questions

Answers

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only ssDNA virus

parvovirus (par one)

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only dsRNA virus

reovirus (REpeatOvirus)

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Naked RNA viruses

NAKED CPR

Calicivirus, Picornavirus, Reovirus

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Which virus acquires its envelop from nuclear membrane

Herpesvirus

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which virus is diploid

retrovirus has 2 identical copies of ssRNA

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Where do DNA viruses replication

2. Exception

nucleus

2. poxvirus (carries its own DNA-dependent RNA pol)

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Where do RNA viruses replication

2. exception

cytoplasm

2. influenza, retrovirus

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DNA viruses

HHAPPPy
Hepadna, Herpes
Adeno
Pox, Pavo, Papova

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All DNA viruses are linear except…

Papovavirus (circular, supercoiled)

Hepadena (circular, incomplete)

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All DNA viruses are ichosahedra except…

POX IN A BOX

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Naked DNA viruses

You need to be naked for a PAP

Papova
Adeno
Parvo

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Enveloped DNA

HPH

Hepadna
Pox
Herpes

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What type of immunity do live attenuated vaccines confer?

2. Why can’t they be given to immunocompromised patients

Humoral and cell-mediated

may revert to virulence

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Immunity conferred by killed vaccines

humoral

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Which vaccines are live attenuated?

MMR
Sabin 
VZV
yellow fever
smallpox
adeno

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Which vaccines are killed?

RIP Always: Rabies, Infulenza, salk Polio, HAV

SalK = Killed

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Egg-based

FRY an egg: Flu, MMR, Yellow fever

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Recombinant vaccine

HBV

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Negative stranded viruses

Always Bring Polymerase or Fail Replication
Arenavirus
Bunyavirus
Paramyxovirus
Orthomysovirus
Filovirus
Rhabdovirus

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Segmented Viruses

BOAR

Bunya
Orthomyo
arena
reo

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Picornavirus

PERCH on a “peak”

Polio
Echo
Rhino
Coxsachie
HAV

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MCC infantile gastroenteritis

Rota

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MCC common cold

rhino

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Name the 4 paramyxoviruses

``` PaRaMyxovirus: Parainfluenza - croup RSV - bronchiolitis in babies Measles Mumps ```

Mumps: Virus, symptoms

1. paramyovirus w/ 1 serotype | 2. Parotitis, orchitis, aspetic Meningitis

Koplik spots

measles

Measles symptoms

3C's: cough, coryza, conjunctivitis

Measles describe rash

head to toe spread

Measles complications

subacute sclerosing panencephalitis SSPE encephalitis giant cell pneumonia

Influenza prophylaxis and tx

Influenza A prophylaxis: Amantadine and rimantadine A and B: Zanamivir and osteltamivir

negri bodies

rabies

bullet-shaped capsid

rabies

HSV-1: diseases

Gingivostomatitis Keratoconjunctivitis oral (and some gential) lesions temporal lobe encephalitis

heterophilic + mono

EBV

roseola (exanthem subitum)

HHV-6

adenovirus: diseases

``` pharyngitis & pneumonia ARD PCF Keratoconjunctivitis GU infections enteric infections ```

fifth disease

B19 parvovirus

parvovirus: diseases

fifth disease - erythema infectiosum hydrops fetalis aplastic crises in sickle cell disease

HHV8

kaposi sarcoma

papova: diseases

HPV JC - progressive multifocal leukoencephalopathy BK

Pox: diseases

small pox vaccinia - cowpox molluscum contagiosum

coxsackie: diseases

aspeptic meningitis herpangina hand/foot/mouth disease myocarditis

calicivirus: diseases

HEV | norwalk - gastroenteritis

Reo: diseases

Reo - colorado tick fever | rota

#1 cause of fatal diarrhea in children

rotavirus (reovirus)

Flavi: diseases

``` HCV Yellow fever dengue st. louis encephalitis west nile ```

Togavirus: diseases

Rubella (germal measles) WEE EEE

Retro: diseases

HIV - AIDS | HTLV - T cell leukemia

Cornonavirus: diseases

corona | SARS

Paramyxovirus: diseases

Parainfluenza - croup RSV - bronchioliltis in babies Measles Mumps

Filo: diseases

Ebola/marburg hemorrhagic fever

arena: diseases

LCV - lymphocytic choriomeningitis | Meningitis - spread by mice

Bunyavirus: diseases

California encephalitis sandfly/rift valley fever crimean-congo hemorrhagic fever hantavirus - hemorrhagic fever, pneumonia

mechanism of antigenic shift and drift

shift - genetic reassortment drift - mutations Sudden Shift is more deadly than a graDual Drift

Arbovirusus

Borne virus: flavi, toga, bunyavirus | transmitted by arthropods

high fever, black vomitus, jaundice, councilman bodies (acidophilic inclusions)

Yellow fever (flavi)

Atypical lymphocytes

mono caused by EBV

Diagnosis of HSV

Tzanck test - look for multinucleated giant cells Tzanck heavens I do not have herpes

Hepatitis serologic markers: best test to detect active HAV

IgM HAV Ab

Hepatitis serologic markers: continued presence indicates carrier state

HBsAg

Hepatitis serologic markers: immunity to HBV

HBsAb

Hepatitis serologic markers: core of HBV

HBcAg

Hepatitis serologic markers: Ab + during window phase

HBc Ab | IgM is an indicator of recent disease

Hepatitis serologic markers: indicator of transmissibility

HBeAg

Hepatitis serologic markers: low transmissibility

HBeAb

Hepatitis serologic markers: + during Acute Disease

``` HBsAg HBcAB (IgM = acute, IgG = chronic) ```

Hepatitis serologic markers: + during complete recovery

HBsAb | HBcAb

Where are gp41 and gp120 found

envelop proteins of HIV

DOC for Onchocerciasis

rIVER blindness is treated with IVERmectin

USMLE Micro virology Flashcards

(70 cards)