USMLE Micro virology Flashcards Preview

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Flashcards in USMLE Micro virology Deck (70):
1

Questions

Answers

2

only ssDNA virus

parvovirus (par one)

3

only dsRNA virus

reovirus (REpeatOvirus)

4

Naked RNA viruses

NAKED CPR

Calicivirus, Picornavirus, Reovirus

5

Which virus acquires its envelop from nuclear membrane

Herpesvirus

6

which virus is diploid

retrovirus has 2 identical copies of ssRNA

7

1. Where do DNA viruses replication
2. Exception

1. nucleus
2. poxvirus (carries its own DNA-dependent RNA pol)

8

1. Where do RNA viruses replication
2. exception

1. cytoplasm
2. influenza, retrovirus

9

DNA viruses

HHAPPPy
Hepadna, Herpes
Adeno
Pox, Pavo, Papova

10

All DNA viruses are linear except...

Papovavirus (circular, supercoiled)
Hepadena (circular, incomplete)

11

All DNA viruses are ichosahedra except...

POX IN A BOX

12

Naked DNA viruses

You need to be naked for a PAP

Papova
Adeno
Parvo

13

Enveloped DNA

HPH

Hepadna
Pox
Herpes

14

1. What type of immunity do live attenuated vaccines confer?
2. Why can't they be given to immunocompromised patients

Humoral and cell-mediated
may revert to virulence

15

Immunity conferred by killed vaccines

humoral

16

Which vaccines are live attenuated?

MMR
Sabin
VZV
yellow fever
smallpox
adeno

17

Which vaccines are killed?

RIP Always: Rabies, Infulenza, salk Polio, HAV

SalK = Killed

18

Egg-based

FRY an egg: Flu, MMR, Yellow fever

19

Recombinant vaccine

HBV

20

Negative stranded viruses

Always Bring Polymerase or Fail Replication
Arenavirus
Bunyavirus
Paramyxovirus
Orthomysovirus
Filovirus
Rhabdovirus

21

Segmented Viruses

BOAR

Bunya
Orthomyo
arena
reo

22

Picornavirus

PERCH on a "peak"

Polio
Echo
Rhino
Coxsachie
HAV

23

MCC infantile gastroenteritis

Rota

24

MCC common cold

rhino

25

Name the 4 paramyxoviruses

PaRaMyxovirus:
Parainfluenza - croup
RSV - bronchiolitis in babies
Measles
Mumps

26

Mumps: Virus, symptoms

1. paramyovirus w/ 1 serotype
2. Parotitis, orchitis, aspetic Meningitis

27

Koplik spots

measles

28

Measles symptoms

3C's: cough, coryza, conjunctivitis

29

Measles describe rash

head to toe spread

30

Measles complications

subacute sclerosing panencephalitis SSPE
encephalitis
giant cell pneumonia

31

Influenza prophylaxis and tx

Influenza A prophylaxis: Amantadine and rimantadine

A and B: Zanamivir and osteltamivir

32

negri bodies

rabies

33

bullet-shaped capsid

rabies

34

HSV-1: diseases

Gingivostomatitis
Keratoconjunctivitis
oral (and some gential) lesions
temporal lobe encephalitis

35

heterophilic + mono

EBV

36

roseola (exanthem subitum)

HHV-6

37

adenovirus: diseases

pharyngitis & pneumonia
ARD
PCF
Keratoconjunctivitis
GU infections
enteric infections

38

fifth disease

B19 parvovirus

39

parvovirus: diseases

fifth disease - erythema infectiosum
hydrops fetalis
aplastic crises in sickle cell disease

40

HHV8

kaposi sarcoma

41

papova: diseases

HPV
JC - progressive multifocal leukoencephalopathy
BK

42

Pox: diseases

small pox
vaccinia - cowpox
molluscum contagiosum

43

coxsackie: diseases

aspeptic meningitis
herpangina
hand/foot/mouth disease
myocarditis

44

calicivirus: diseases

HEV
norwalk - gastroenteritis

45

Reo: diseases

Reo - colorado tick fever
rota

46

#1 cause of fatal diarrhea in children

rotavirus (reovirus)

47

Flavi: diseases

HCV
Yellow fever
dengue
st. louis encephalitis
west nile

48

Togavirus: diseases

Rubella (germal measles)
WEE
EEE

49

Retro: diseases

HIV - AIDS
HTLV - T cell leukemia

50

Cornonavirus: diseases

corona
SARS

51

Paramyxovirus: diseases

Parainfluenza - croup
RSV - bronchioliltis in babies
Measles
Mumps

52

Filo: diseases

Ebola/marburg hemorrhagic fever

53

arena: diseases

LCV - lymphocytic choriomeningitis
Meningitis - spread by mice

54

Bunyavirus: diseases

California encephalitis
sandfly/rift valley fever
crimean-congo hemorrhagic fever
hantavirus - hemorrhagic fever, pneumonia

55

mechanism of antigenic shift and drift

shift - genetic reassortment
drift - mutations

Sudden Shift is more deadly than a graDual Drift

56

Arbovirusus

Borne virus: flavi, toga, bunyavirus
transmitted by arthropods

57

high fever, black vomitus, jaundice, councilman bodies (acidophilic inclusions)

Yellow fever (flavi)

58

Atypical lymphocytes

mono caused by EBV

59

Diagnosis of HSV

Tzanck test - look for multinucleated giant cells

Tzanck heavens I do not have herpes

60

Hepatitis serologic markers: best test to detect active HAV

IgM HAV Ab

61

Hepatitis serologic markers: continued presence indicates carrier state

HBsAg

62

Hepatitis serologic markers: immunity to HBV

HBsAb

63

Hepatitis serologic markers: core of HBV

HBcAg

64

Hepatitis serologic markers: Ab + during window phase

HBc Ab
IgM is an indicator of recent disease

65

Hepatitis serologic markers: indicator of transmissibility

HBeAg

66

Hepatitis serologic markers: low transmissibility

HBeAb

67

Hepatitis serologic markers: + during Acute Disease

HBsAg
HBcAB (IgM = acute, IgG = chronic)

68

Hepatitis serologic markers: + during complete recovery

HBsAb
HBcAb

69

Where are gp41 and gp120 found

envelop proteins of HIV

70

DOC for Onchocerciasis

rIVER blindness is treated with IVERmectin