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Flashcards in Uvea Deck (14)
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Parts of the uvea

• Iris - forms pupil
• Ciliary body
– Makes aqueous humour • Choroid
– Supplies retina


Uveal cysts

• Posterior iris or ciliary body in origin


Persistent pupillary membranes

When the iris/vasculature of the eye early on, they don't rarify or degenerate as they should leaving you remnants, e.g. persistent pupillary membranes
Strand starting at the iris & ending at the iris, etc.
Iris to cornea or iris to lens - don't breed
• Iris to iris, iris to cornea, iris to lens


Iris coloboma

Congenital hole in the iris.


Iris atrophy

Common thing you'll see in a small dog. Can be quite mild. Nothing we can do. Old age condition. Don't go in bright lights. May squint, tear more.



Inflammation of uveal tract. Can get leakage of blood vessels because they are more permeable. Prostaglandins released. Inflammatory products will impact on each other. Nitrous oxide, TGF2beta, that will compound the problem leading to uveitis. Sometimes it can be mostly in the anterior or posterior uveitis, but all uveitis will always be to some degree a panuveitis. Will also have an inflammation of the scleral tissue- inflammation of all the tuniques of the eye. Endopthalmitis.


Uveitis - clinical sigsn

Prolapse of your third eyelid
Red eye (bleeding, dilation etc)
Corneal edema, or aqueous flair(protein leaked into the aqueous so that it is turbid/plasmoid aqueous).
Aqueous flare
Vitreal flare
Retinal lesions


Uveitis - causes

• Infectious
• Immune-mediated
• Breed related
• Trauma
• Neoplasia
• Idiopathic


Uveitis - diagnosis

• Clinical signs
• Low intraocular pressures • Blood tests
• Chest radiographs
• abdominal ultrasound
• Additional tests – Serum titers
– Biopsy


Uveitis - Treatment

• Treat underlying cause
• Anti-inflammatory therapy (if you don't you may lose the eye)
– Topical (strongest Prednisolone acetate 1%, dex second)
– Systemic
• Cycloplegia


Uveitis sequelae

• Cataract
• Posterior synechiae • Glaucoma
• Lens luxation
• Retinal detachment


Uveitis neoplasia - melanoma

Most common tumour of the uvea. It's usually benign, (dog), most likely in the iris or the ciliary body, and if it's caught early enough you can laser it with a diode laser. If you catch it too late, you do need to enucleate.


Uvea - adenoma/carcinoma

– +/- pigment
– Histopathology
– Resection (if they are small enough, but they can hide behind the iris)
– Diode laser
– Enucleation


Uvea - lymphoma

Usually secondary, so does lower your survival rate. When they start on chemo, it does respond.