Flashcards in Uvea Deck (14)
Parts of the uvea
• Iris - forms pupil
• Ciliary body
– Makes aqueous humour • Choroid
– Supplies retina
• Posterior iris or ciliary body in origin
Persistent pupillary membranes
When the iris/vasculature of the eye early on, they don't rarify or degenerate as they should leaving you remnants, e.g. persistent pupillary membranes
Strand starting at the iris & ending at the iris, etc.
Iris to cornea or iris to lens - don't breed
• Iris to iris, iris to cornea, iris to lens
Congenital hole in the iris.
Common thing you'll see in a small dog. Can be quite mild. Nothing we can do. Old age condition. Don't go in bright lights. May squint, tear more.
Inflammation of uveal tract. Can get leakage of blood vessels because they are more permeable. Prostaglandins released. Inflammatory products will impact on each other. Nitrous oxide, TGF2beta, that will compound the problem leading to uveitis. Sometimes it can be mostly in the anterior or posterior uveitis, but all uveitis will always be to some degree a panuveitis. Will also have an inflammation of the scleral tissue- inflammation of all the tuniques of the eye. Endopthalmitis.
Uveitis - clinical sigsn
Prolapse of your third eyelid
Red eye (bleeding, dilation etc)
Corneal edema, or aqueous flair(protein leaked into the aqueous so that it is turbid/plasmoid aqueous).
Uveitis - causes
• Breed related
Uveitis - diagnosis
• Clinical signs
• Low intraocular pressures • Blood tests
• Chest radiographs
• abdominal ultrasound
• Additional tests – Serum titers
Uveitis - Treatment
• Treat underlying cause
• Anti-inflammatory therapy (if you don't you may lose the eye)
– Topical (strongest Prednisolone acetate 1%, dex second)
• Posterior synechiae • Glaucoma
• Lens luxation
• Retinal detachment
Uveitis neoplasia - melanoma
Most common tumour of the uvea. It's usually benign, (dog), most likely in the iris or the ciliary body, and if it's caught early enough you can laser it with a diode laser. If you catch it too late, you do need to enucleate.
Uvea - adenoma/carcinoma
– +/- pigment
– Resection (if they are small enough, but they can hide behind the iris)
– Diode laser