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CSIM 2017 > Viral Infections > Flashcards

Viral Infections Flashcards

1
Q

HEV is associated with what type of food?

A

Uncooked pork (sausages)

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2
Q

HEV has a higher mortality in which group of individuals?

A

Pregnant women

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3
Q

How is HAV, HBV, HCV, HDV and HEV spread respectively?

A

HAV and HEV: Enteral spread
HBV: Blood products, sexual activity and vertical transmission
HCV: Blood products and IV drug abuse
HDV: unsure, may be same as HBV

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4
Q

Which 2 viruses are the most common cause of viral gastroenteritis?

A

Rotavirus and Norovirus

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5
Q

What are the 3 common symptoms of viral gastroenteritis?

A

Diarrhoea, Vomiting and Abdominal cramps

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6
Q

Which virus is similar to Norovirus? How are they different?

A

Sappovirus.

Sappovirus results in more diarrhoea than vomiting, but Norovirus causes more vomiting than diarrhoea.

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7
Q

Incubation period of Rotavirus

A

48 hours

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8
Q

Symptoms of Rotavirus

A

Watery diarrhoea and vomiting, fever and abdominal pain

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9
Q

How long do the symptoms of Rotavirus last?

A

4 - 8 hours

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10
Q

Name the 2 licensed vaccines that are against Rotavirus. Which is more common? Describe the more common vaccine, including its route of administration and the dosage.

A

Rotarix and Rotateq
Rotarix is more common. Live attenuated vaccine. Given orally as 2 doses, 8 weeks and 12 weeks old. Minimum of 4 weeks between doses.

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11
Q

Which virus causes “winter vomiting disease”?

A

Norovirus

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12
Q

What is the incubation period of Norovirus?

A

1 - 2 days

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13
Q

What are the symptoms of Norovirus and how long do the symptoms last?

A

Sudden onset of severe vomiting and diarrhoea.

Last for 1 - 2 days.

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14
Q

What is the classical sign of Molluscum Contagiosum?

A

Raised, firm papules on the skin, with a characteristic small dimple in the middle. Spots aren’t painful but are itchy.

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15
Q

What is the cause of malar rash? What is the disease caused by this virus?

A

Parvovirus B19.

Causes Erythema Infectiosum, a.k.a. the Fifth Disease

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16
Q

What is the cause of Hand, Foot and Mouth Disease?

A

An enterovirus - Coxsackie virus

17
Q

What is the genetics of Parvovirus B19?

A

ssDNA non-enveloped

18
Q

What does parvovirus B19 infects?

Which 2 groups of patients are of increased concern if infected with Parvovirus B19?

A

RBC progenitor cells

  1. People with RBC disease
  2. Pregnant women or the immunocompromised
19
Q

What causes genital warts? Give the serotypes

A

Human Papillomavirus (HPV) Serotypes 6,11,16 and 18

20
Q

What is the clinical name for genital warts

A

Condylomata Acuminata

21
Q

Which virus is the main cause of bronchiolitis?

A

Respiratory Syncytial virus

22
Q

Which virus is the common cause of viral encephalitis?

A

Herpes Simplex Virus (HSV)

23
Q

What is the genetic material of HSV?

A

Positive strand RNA virus

24
Q

A 22 year old presents with a 5 day history of fever. On examination, discrete cervical lymph nodes are palpable bilaterally. What is the likely virus that causes this?

A

Mumps

25
Q

What is a clinical feature of symptomatic congenital CMV infection?

A

Hepatosplenomegaly

26
Q

Kaposi’s Sarcoma is associated with which virus?

A

HHV8

27
Q

Which virus causes cold sores upon reactivation?

A

HSV

28
Q

Which viruses are associated with congenital cataracts?

A

Rubella and HSV1

29
Q

What serotypes of a virus causes cervical cancer?

A

HPV 16 and 18

30
Q

Aciclovir is commonly used to treat which two viral infections?

A

VZV (shingles) and Herpes Simplex

31
Q

What are the two conditions that can be caused by HSV?

A

Genital herpes and cold sores.

32
Q

Which virus is the most common cause of congenital infection is in the UK?

A

CMV - Cytomegalovirus

33
Q

Which of the following virus is not a recognised cause of hepatitis?

a) HepA
b) HepB
c) HepD
d) HepF

A

Hep F

34
Q

Which virus can cause post transplant lymphoproliferative disease?

A

EBV

35
Q

EBV is latent in which cells?

A

B lymphocytes and epithelial cells

36
Q

What is the other name for EBV? What is the genetic structure of EBV?

A

EBV is otherwise known as HHV4.

Has a dsDNA.

CSIM 2017 (20 decks)

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