virology Flashcards

(59 cards)

1
Q

are viruses cellular?

A

no

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2
Q

viruses depend on what for reproduction

A

host cell metabolism

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3
Q

3 variations in size

A

poxvirus, parvovirus, prions

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4
Q

prion

A

“virus like” protein

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5
Q

what scope to use to see virus

A

electron scope

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6
Q

spongiforms, infectious, neurologic type disorders

A

prions

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7
Q

3 ways to classify a virus

A

shape, composition, envelope

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8
Q

what is an envelope virus

A

lipid membrane that surrounds the virus

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9
Q

envelope viruses are produced by

A

budding through the host cells membranes

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10
Q

what fuses to hosts cell membrane allowing capsid and viral genome to enter host and cause infection

A

envelope viruses

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11
Q

what viruses don’t have an envelope

A

naked envelope AKA non-envelope

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12
Q

what kind of viruses are more difficult to kill

A

naked viruses

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13
Q

naked viruses require

A

steam sterilization

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14
Q

4 stages of replication

A

attachment, penetration/uncoating, replication & synthesis, assembly & release

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15
Q

top 3 cells viruses will attach to

A
  1. respiratory 2. urogenital 3. GI tract
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16
Q

penetration/uncoating means

A

penetration-entry of virus genome into host cell

uncoating- virus produce enzymes that degrade host cell membrane

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17
Q

what enters host cell during penetration

A

nucleic acid core

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18
Q

what remains on host cell exterior during penetration

A

the capsid/ outer shell

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19
Q

replication stage- immune system cant respond because

A

virus is hidden

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20
Q

prodromal period

A

the time right before clinical signs

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21
Q

2 methods of replication

A

lysogenic or lytic

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22
Q

which method of replication occurs after the viral infection is over

A

lysogenic

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23
Q

viral infections affect the host in 2 ways

A

apparent and non-apparent

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24
Q

apparent

A

clinical disease: acute or chronic

25
non-apparent
no clinical signs
26
feline herpes virus
causes rhinotracheitis. runny nose, C+, S+, F+ anorexic, ulcers, eyes sealed shut. contagious
27
which feline dz is similar to k9 parvo
feline distemper
28
feline parvovirus
attacks neonatal brain- causes neurological problems, lymphatic tissue and bone marrow
29
what kind of virus is FeLV
retrovirus
30
what kind of virus is FIV
lentivirus
31
which is a DNA virus
feline distemper
32
canine herpesvirus may be the cause of
fading puppy syndrome
33
which virus is the paromyxo virus
canine distemper
34
hyperkaratosis on root pads found with this disease
canine distemper
35
which viruses are contagious
feline herpesvirus, canine distemper virus, canine coronavirus
36
canine adenovirus
cause of hepatitis (similar to parvo)
37
canine rotavirus infects what system
GI system, secondary dz can be obtained
38
how long does a virus last without refrigeration
3 weeks
39
what to do with postmortem tissues
place in 10% formalin and label- dont freeze
40
why cant we freeze tissues
alters tissues
41
what disease should be checked multiple times in fear it may turn up positive
lyme disease
42
how long for results? fluorescent antibody test
1 hour
43
in house fluorescent antibody tests anything but
rabies
44
what 3 things appear on the elisa snap
felv, parvo, hwt
45
antiviral antibodies absorbed into microscopic latex beads..
latex agglutination test
46
antigen vs antibody
antigen is a foreign body that could cause disease | antibody is a protein that fights off disease. immunity
47
direct fluorescent antibody test
used to identify specific microorganisms- antigens
48
indirect fluorescent antibody test
used to demonstrate the presence of antibodies against a antigen
49
how is the FA viewed under direct FA
fluorescent microscope, plate reader, fluorescence-activated flow cytometer
50
can be used to detect, count and separate cells labeled with fluorescent antibodies
flow cytometry
51
the interaction of particulate antigens with antibodies leads to
agglutination reactions
52
direct agglutination vs indirect agglutination
direct- test pt serum for presence of antibodies against large, cellular antigens. indirect- test pt serum for presence of antibodies against soluble antigens
53
is lytic more common than lysogenic
yes
54
lytic cycle
viral DNA destroys cell DNA. contains symptoms of infection. virulent viral infection occurs.
55
is lytic or lysogenic faster
lytic
56
lysogenic cycle
viral DNA merges with cell DNA- doesnt destroy. | no symptoms of viral infection. temperate viral replication occurs.
57
which stage produces progeny phages
lytic
58
when does lysogenic typically occur
when the viral infection is over, but may be permanent.
59
how would a lysogenic turn into lytic cycle
stress, mutation, exposed to UV radiation