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Flashcards in Virology Deck (9)
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1

As a general rule, RNA viruses are single-straded and replication in the___ while DNA viruses are double-stranded and replicate in the___.

RNA = cytoplasm
DNA = nucleus

2

What is the best definition of heterophile antibodies as produced in EBV infection?

hint: Ig__ with affinity for what?

IgM antibodies with affinity for beef RBC (sheep and horse RBCs)

3

Which protein is expressed very early in HIV infection and its detection in assays has been used to diagnose seroconversion in HIV?

p24

4

Virus transport medium containing pcn, gent and ampho is used to collect and transport specimens for viral testing because this medium does what?

It inhibits bacterial and fungal growth

5

Which of the following statements about herpesviruses are true except which one:
1. there are eight of them
2. they're morphologically identical
3. they're all DNA viruses
4. They all cause a vesicular rash
5. They can all remain latent

4 is false - EBV doesn't present with a rash

6

Which of the following statements about herpesviruses are true except which one:
1. there are eight of them
2. they're morphologically identical
3. they're all DNA viruses
4. They all cause a vesicular rash
5. They can all remain latent

4 is false - EBV doesn't present with a rash

7

What test is the primary screening test for HIV?

serum enzyme linked immunoassay

8

What virus are cold sores associated with?

HSV1

9

At the end of 40 cycles of PCR, how many DNA molecules are theoretically present in the reaction if one starts with one ds DNA molecule as the template?

2^40 (because there were two strands)