Coagulation Exercises Flashcards Preview

Labs Medicine > Coagulation Exercises > Flashcards

Flashcards in Coagulation Exercises Deck (8)
Loading flashcards...
1

A patient with menorrhagia, gum bleeding, and easy bruising likely has dysfunction of what aspect of the coagulation cascade?

platelet dysfunction

2

What will type 1 von willebrand disease look like on labs?

low Factor 8
low vWF antigen
low ristocetin cofactor activity

normal distribution of vWF factor multimer analysis

3

What will type 2a vWF def look like on labs?

low Factor 8
low vWF antigen
low Ristoceint cofactor activity
**decreased high molecular weight multimers on the von willebrand factor multimer analysis**

4

What will type 2n vWF def look like on labs?

**severely low factor 8**
normal vWF antigen
Normal ristocetin cofactor
normal multiple analysis

5

What will type 3 vWF def look like on labs?

very low factor 8
very low vWF antigen
very low ristocein cofactor activity

so very low in all 3!

6

What do the PFA-100Col/Epi and PFA-100 Col/ADP tests look at in general terms?

palatelet function

if they are prolonged, there's something wrong with how the platelets reacct to epi and ADP

7

What medication will increase the Col/Epi test, but not the Col/ADP test?

aspirin

8

Will thrombocytopenia increase the PFA EPI and PFA ADP test?

yes