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Virology Flashcards

(61 cards)

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1
Q

Mnemonic-Naked Viruses

A

NAKED CPR and PAPP smear
Calici
Picorna
Reo

Parvo
Adeno
Papilloma
Polyoma

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2
Q

Mnemonic-Segmented Genome

A 
B-O-A-R
Bunyaviruses
Orthomyxoviruses (influenza)
Arenaviruses
Reoviruses
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3
Q

Mnemonic-Negative-Strand RNA Viruses

A 
Always Bring Polymerase Or Fail Replication.
Arenaviruses
Bunyaviruses
Paramyxoviruses
Orthomyxoviruses
Filoviruses
Rhabdoviruses
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4
Q

Mnemonic-Live-Attenuated Vaccines

A

LIVE! One night only!
See your yellow chickens get vaccinated with Sabin’s and MMR
yellow fever, chicken fox (VZV), Sabin’s Polio,MMR

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5
Q

Mnemonics - Salk Polio Vaccine

A

SalK polio vaccine = Killed

Killed Vaccines
RIP Always!
Rabies
Influeza
Polio (Salk's)
Hepatitis A
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6
Q

Mnemonics-DNA Viruses

A 
DNA Viruses are HHAPPPPy viruses
Hepadna
Herpes
Adeno
Pox
Parvo
Polyoma
Papilloma
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7
Q

All DNA viruses have doubled-stranded DNA EXCEPT

A

Parvovirus

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8
Q

All DNA virus have linear DNA EXCEPT

A

Papilloma
Polyoma and
Hepadna

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9
Q

All DNA viruses are icosahedral EXCEPT

A

Poxvirus

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10
Q

All DNA viruses replicate in the nucleus EXCEPT

A

Poxvirus

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11
Q

Parvovirus B19 is

A

MOT: respiratory transplacental
Oncogenic: No
Vaccine: No

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12
Q

Adenovirus is

A

MOT: respiratory, fecal-oral
Oncogenic: No
Vaccine: Yes

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13
Q

Human Papillomavirus is

A

MOT: sexual, skin contact
Oncogenic: Yes
Vaccine: Yes

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14
Q

What is the manifestation and route of transmission of HSV-1?

A

Primary Infection: Stomatitis

Recurrent Infection: Herpes labialis, encephalitis

Route of Transmission: Secretions and saliva

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15
Q

What is the manifestation and route of transmission of HSV-2?

A

Primary Infection: Herpes genitalis, perinatal infection

Recurrent Infection: Herpes genitalis

Route of Transmission: Sexual, Perinatal Infection

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16
Q

What is the manifestation and route of transmission of VZV?

A

Primary Infection: Varicella

Recurrent Infection: Zoster

Route of Transmission: Via respiratory secretions

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17
Q

What is the manifestation and route of transmission of EBV?

A

Primary Infection: Infectious Mononucleosis

Recurrent Infection: None

Route of Transmission: Via respiratory secretions and Saliva

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18
Q

What is the manifestation and route of transmission of CMV?

A

Primary Infection: Congenital, Mononucleosis

Recurrent Infection:Asymptomatic shedding

Route of Transmission: Intrauterine, transfusions, sexual contact, secretions

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19
Q

What is the manifestation and route of transmission of HHV-8?

A

Primary Infection: Uncertain

Recurrent Infection: Kaposi’s sarcoma

Route of Transmission: Sexual or organ transplantation

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20
Q

Mnemonics-Herpesviruses

A 
Get HERPES on a CHEVrolet!
CMV
HSV
EBV
VZV
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21
Q

Where is the site of latency for HSV-1 and HSV-2?

A

HSV-1 Trigeminal ganglia

HSV-2 Lumbosacral ganglia

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22
Q

Mnemonic-Tzanck Smear

A

Tzanck heavens I do not have herpes!

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23
Q

Uses of aspirin in pediatric diseases

A

Kawasaki
ARF
JRA

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24
Q

Mnemonics-Hepatitides

A

Hepatitis A = Asymptomatic
Hepatitis B = Blood-borne
Hepatitis C = Chronic, Cirrhosis, Carcinoma, Carriers
Hepatitis E = Enteric, Expectant mothers, Epidemics

The VOWELS (A and E) hit your BOWELS.
Hepatitis A and E cause enteric infections.
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25
Hepatitis B Profile | INCUBATION PERIOD
HBsAG: Positive Anti-HBs: Negative Anti-HBc: Negative HBeAg: Positive
26
Hepatitis B Profile | ACUTE INFECTION
HBsAG: Positive Anti-HBs: Negative Anti-HBc: Positive IgM HBeAg: Positive
27
Hepatitis B Profile | WINDOW PERIOD
HBsAG: Negative Anti-HBs: Negative Anti-HBc: Positive IgM HBeAg: Negative
28
Hepatitis B Profile | COMPLETE RECOVERY
HBsAG: Negative Anti-HBs: Positive Anti-HBc: Positive IgG HBeAg: Negative
29
Hepatitis B Profile | CHRONIC CARRIER
HBsAG: Positive Anti-HBs: Negative Anti-HBc: Positive IgG HBeAg: Negative
30
Hepatitis B Profile | CHRONIC ACTIVE
HBsAG: Positive Anti-HBs: Negative Anti-HBc: Positive IgG HBeAg: Positive
31
Hepatitis B Profile | VACCINATED
HBsAG: Negative Anti-HBs: Positive Anti-HBc: Negative HBeAg: Negative
32
Mnemonics-RNA Viruses
I went to a RETRO TOGA party, where I drank FLAVored CORONA beer and ate HIPPY CALIfornia PICkles. RETROvirus, TOGAvirus, FLAVivirus, CORONAvirus, HEPEvirus, CALIcivirus, PICornavirus
33
All RNA viruses have single-stranded DNA EXCEPT
Reovirus and Rotavirus
34
All DNA viruses replicate in the cytoplasm EXCEPT
Influenza and Retrovirus
35
Mnemonics-Picornaviridae
``` PERCHed on a PIC (peak). Poliovirus Echovirus Rhinovirus Coxsackievirus Hepatis A virus PICornaviridae ```
36
Mnemonic-Rhinovirus
RHINO has a runny nose.
37
Mnemonic-Rotavirus
Right Out The Anus | ROTAvirus causes diarrhea!
38
Mnemonics-Antigenic Shifts VS Drifts
Sudden Shift is more deadly than graDual Drift. antigenic Shifts cause PANDEMICS antigenic Drifts cause EPIDEMICS
39
Mnemonic-Paramyxoviruses
``` PaRaMyxoviruses Parainfluenza virus RSV Measles virus Mumps virus ```
40
Envelope Spikes | MEASLES
Hemagglutinin: + Neuraminidase: - Fusion Protein: +
41
Envelope Spikes | MUPMS
Hemagglutinin: + Neuraminidase: + Fusion Protein: +
42
Envelope Spikes | RSV
Hemagglutinin: - Neuraminidase: - Fusion Protein: +
43
Envelope Spikes | PARAINFLUENZA
Hemagglutinin: + Neuraminidase: + Fusion Protein: +
44
Mnemonics-Cardinal Manifestations of Measles
``` 3 Cs Cough Coryza Conjunctivitis Koplik spots ```
45
Mnemonics-Mumps
Mupms makes your parotids and testes as big as POM-poms. Parotitis Orchitis Meningitis (aseptic)
46
What is considered CATEGORY I in animal bites?
Touching or feeding animals, licks on the skin --> no treatment
47
What is considered CATEGORY II in animal bites?
Nibbling of uncovered skin, minor scratches or abrasions without bleeding, licks or broken skin --> vaccine
48
What is considered CATEGORY III in animal bites?
Single or Multiple transdermal bites or scratches, contamination of mucous membrane with saliva from licks; exposure to bat bites or scratches --> vaccine + Immunoglubulin
49
Mnemonic-Congenital Rubella Syndrome
``` 5 Bs of Congenital Rubella Syndrome Bulag (cataracts) Bingi (sensorineural deafness) Bobo (mental retardation) Butas ang Puso (PDA) Blueberry Muffin (baby) ```
50
HIV structural genes: | gag
p24, p7 = Nucleocapsid | p17 = Matrix
51
HIV structural genes: | pol
reverse transcriptase = transcribes RNA genome into DNA protease = cleaves precursor polypeptides integrase = integrates viral DNA into host cell DNA
52
HIV structural genes: | env
``` gp120 = attachment to CD4 protein / Antigenicity changes rapidly gp41 = fusion with host cell ```
53
HIV regulatory genes: | tat
Protein: tat | Activation of transcription of viral genes
54
HIV regulatory genes: | rev
Protein: rev | Transport of late mRNAs to cytoplasm
55
HIV regulatory genes: | nef
``` Protein: nef Decrease CD4 and class I MHC proteins ```
56
HIV regulatory genes: | vif
Protein: vif | Enhances hypermutation
57
HIV regulatory genes: | vpr
Protein: vpr | Transport in nondividing cells
58
HIV regulatory genes: | vpu
Protein: vpu | Enhances virion release
59
AIDS-DEFINING ILLNESSES | CD4 <500
M.tuberculosis --> disseminated tuberculosis HSV --> HSV esophagitis C. albicans --> esophageal candidiasis HHV-8 --> Kaposi's sarcoma
60
AIDS-DEFINING ILLNESSES | CD4 <200
``` P. jiroveci --> PCP pneumonia T. gondii --> cerebral toxoplasmosis C. neoformans --> meningoencephalitis C. immitis --> coccidiodomycosis C. parvum --> chronic diarrhea ```
61
AIDS-DEFINING ILLNESSES | CD4 <50
M. avium --> invasive pulmonary disease H. capsulatum --> histoplasmosis CMV --> CMV retinitis

Microbiology (8 decks)

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