Viruses Flashcards Preview

Micro/Immuno Part 2 > Viruses > Flashcards

Flashcards in Viruses Deck (10):
1

overview

-all forms of life have viruses
-they have co evolved with their hosts
-altered our history-AIDS, smallpox, flu
-many concepts and tools of molecular tools came from studying viruses
>4000 discovered

2

filterable agents

-when filtered bacteria on 220 nm, filter became infectious
-when filtered viruses on 220 nm, filtrate was infectious
-viruses need to be seen using electron microscopes
-obligate intracellular--couldn't culture on plates

3

definition of a virus

-capsid encoding organism
-associated with all life forms
-obligate intracellular parasites

4

capsid

protein shell that encapsulates the nucleic acid genome

5

virion

particle encoded by virus genome-capsid and genome and other parts

6

modular genomes

-contain capsid protein genes-stuctural proteins
-replicon-emzymes to copy the genome
-host cell interacting factors-non-structural proteins

7

capsid stuctures

-helical symmetry
-icosahedral symmetry

8

virion structure

-genome
-capsid
-maybe envelope
-capsid shape and genome type independent

9

virus classification

-host cell (kingdom)-eukaryotic, prokaryotic, plant, animal, insect
-genome type-RNA/DNA, single or double stranded
-virion structure-enveloped or naked, helical, icosahedral, complex

10

virion components

-genome segment
-nucleocapsid
-capsid of core
-tegument
-matrix
-envelope
-glycoprotein
-spike or fiber
-see slides for examples