Viruses

Question 1

what type of virus is HIV

Answer 1

+ssRNA

Question 2

what type of virus is Influenza A

Answer 2

-ssRNA

Question 3

large dsDNA enveloped virus

Answer 3

Herpes

Question 4

small DNA virus

Answer 4

HPV

Question 5

virus that has 2 copies of the +ssRNA and host tRNA with it

Answer 5

HIV

Question 6

virus that is segmented

Answer 6

Influenza A

Question 7

what virus has RNA dependent RNA polymerase

Answer 7

influenza A

Question 8

what virus has RNA dependent DNA polymerase

Answer 8

HIV

Question 9

virus that turns itself from RNA to dsDNA

Answer 9

HIV

Question 10

what enzyme binds viral genome into host genome

Answer 10

integrase

Question 11

stage of HIV where patient presents with flu-like symptoms and viral load of anti-HIV Ab’s is high

Answer 11

stage I

Question 12

stage of HIV where patient is asymptomatic and CD4+ levels can be slightly low or normal, and viral load is undetected

Answer 12

stage II

Question 13

stage of HIV where CD4+ levels are low, patient has detectable viral load, and experiencing weird cancers/deterioration

Answer 13

stage III

Question 14

2 really important opportunistic pathogens for HIV patients w/ AIDS

Answer 14

PCP (pneumocystis) and MAC

Question 15

main drug cocktail used for HIV patients

Answer 15

2 NRTI’s + 1-2 PI’s

Question 16

why can cardiovascular problems arise in patients who have been dealing w/ HIV for a long time?

Answer 16

due to anti-retroviral medications that increase their cholesterol

Question 17

small DNA virus that has up to 200 different types

Answer 17

HPV

Question 18

virus that has 2 capsid proteins and is naked

Answer 18

HPV

Question 19

main players linked for transformation event causing cancer

Answer 19

E6 and E7
(E6-inhibits p53)
(E7-inhibits prb105)

Question 20

virus causes warts

Answer 20

HPV

Question 21

drug used to treat influenza A

Answer 21

oseltamivir (tamiflu)

Question 22

2 topical drugs used to treat warts (HPV)

Answer 22

Imiquimod
podoflox

Question 23

drug that turns TLR7 on and helps clearance of wart

Answer 23

imiquimod

Question 24

drug that arrests cell cycle and helps in clearance of wart

Answer 24

Podoflox

Question 25

HPV types ____and____are common causes of benign warts or benign head and neck tumors

Answer 25

6 and 11

Question 26

transformation event by HPV happens when.....and leads to uncontrollable proliferation

Answer 26

virus accidentally inserts itself into host genome

Question 27

target mucoepithelial cells and are latent in neurons

Answer 27

HSC-1, HSV-2, VZV

Question 28

target B cells and are latent in B cells

Answer 28

EBV

Question 29

target monocytes and lymphocytes and are latent in monocytes and lymphocytes

Answer 29

CMV

Question 30

this virus has DNA dependent DNA polymerase

Answer 30

HSV (herpes)

Question 31

main target for acyclovir (treats most herpes, not EBV or CMV)

Answer 31

thymidine kinase

Question 32

weird virus that buds off nucleus and then leaves cell by exocytosis

Answer 32

HSV (herpes)

Question 33

what causes herpes virus to be latent in neuron

Answer 33

LATs (latency-associated transcripts)

Question 34

what happens during reactivation of herpes

Answer 34

virus moves down same neuron and rapidly replicates

Question 35

direct analysis of HSV infection by scraping the base of a lesion

Answer 35

Tzanck smear

Question 36

look for multi-nucleated giant cells on what to diagnose HSV

Answer 36

tzanck smear

Question 37

2 markers for EBV

Answer 37

EBNA-1 and LMP-2a

Question 38

EBV infects B cell and causes it to make what kind of Ab's

Answer 38

nonspecific IgM

Question 39

what cell (be specific) is EBV latent in

Answer 39

LMP-2a memory B cell

Question 40

triad: exudative pharyngitis, splenomegaly, and lymphadenopathy

Answer 40

EBV and CMV

Question 41

what distinguishes EBV from CMV

Answer 41

EBV is heterophile Ab + and CMV is Ab -

Question 42

difference b/t the cells seen in EBV and CMV

Answer 42

EBV: atypical (Downey) CMV: cytomegalic cell

Question 43

immune response against EBV

Answer 43

T cells

Question 44

immune response against CMV

Answer 44

NK cells

Question 45

over the counter cream to help with HSV-1

Answer 45

Docosanol

Question 46

treatment for CMV

Answer 46

Ganciclovir