Flashcards in Vitamin C Deck (12)
Antioxidant (reducing agent).
Reduces mineral cofactors: norepinephrine synthesis, collagen synthesis, etc.
Reverses oxidation. Electron donator.
Inhibits LDL oxidation which diminishes plaque formation.
Interaction with iron
Enhances absorption of non heme iron.
Keeps iron reduced in collagen and carnitine synthesis.
Urine as ascorbic or dehydroascorbic acid.
Oxidation to dehydroascorbic acid occurs in liver.
90 mg men
75 mg women
Abdominal pain and osmotic diarrhea due to unabsorbed vitamin C in the GI.
Risk of kidney stones in renal PT and iron toxicity in individuals with iron metabolism problems.
Leukocytes reflect body stores.
Red peppers and papaya. OJ.
100% absorption at intake
Transported through blood in free form.
Ascorbic acid: sodium dependent transporter (SVCT1 and SVCT2)
Dehydroascorbic acid: oxidized in GI then transported via glucose transporters (GLUT1 and GLUT3). Competes with glucose.
Reduces DHA back to ascorbic acid.
Spares vitamin C.