Vitamin E Flashcards Preview

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Flashcards in Vitamin E Deck (23):
1

What does tocopherol mean?

Toco = childbirth
Pher = the bring forth
ol = alcohol

2

What is Vitamin E AKA

Vitamers

3

What are the differences of isomers present between natural and synthetic vitamin E?

Natural: only biologically active isomers present

Synthetic: Fatty acid attached, racemic mixture of isomers

4

What is the difference of tocopherols present between natural and synthetic vitamin E?

Natural: mixture of tocopherols and tocotrienols

Synthetic: Alpha-tocopherols only

5

T/F

Vitamin E supplements prevent cancer and heart disease

False

6

How are tocopherols and tocotrienols absorbed?

Fatty acid removed by lipases and bile is released into SI. 50% absorbed by passive diffusion in SI.

7

Where does absorption of tocopherols and tocotrienols happen primarily in the SI?

Jejunum

8

How are tocopherols and tocotrienols transported to the liver?

Packed into chylomicrons

9

What happens to tocopherols and tocotrienols after they go to the liver?

Alph-tocopherol transport protein incorporates most alpha and gamma tocopherol and tocotrienols into VLDL

10

Where is 90% of Vitamin E stored?

Adipose tissue

11

Where is the remaining 10% of vitamin E stored?

Blood, liver, lungs, heart, muscles, adrenal glands, spleen, brain.

12

What are some antioxidant properties of vitamin E?

Found in plasma membrane

Dietary intake decreases risk of heart disease, cancer, age-related macular degen.

Donates H to free radicals to protect PUFA in membrane

13

What is the absolute best source of vitamin E?

Plant oils

14

What sources are high alpha-tocopherols found?

Canola oil, olive oil, sunflower oil, safflower oil, cottonseed oil, almonds

15

What sources are high gamma-tocopherols found?

Corn oil, soybean oil, sesame oil, walnuts, peanuts, pecans

16

What sources are high tocotrienols found?

Oats, rye, barley, rice bran oil, wheat germ, palm oil

17

T/F

Vitamin E deficiency - tocopherols is rare

True

18

What are some key symptoms of hypovitaminosis E?

Myopathy, hemolytic anemia (infants only), loss of tendon reflexes, loss of coordination, peripheral neuropathy

19

Who is most at risk for vitamin E deficiency?

1. Fatty malabs disorder patients
2. Premature infants

20

What is the safe upper limit of Vitamin E?

1,000 mg/day

21

What are the toxicity symptoms of vitamin E (4)

Bleeding
Nausea
Diarrhea
Fatigue

22

What vitamin E intake level is associated with all cause mortality?

400 IU

23

What is the function of vitamin E

Antioxidant