viwuses (or viwowogy)

Question 1

live vaccines?

Answer 1

smallpox
yellow fever
rotavirus
chickenpox
sabin (OPV)
MMR
intranasal flu

Question 2

killed vaccines?

Answer 2

rabies
injected flu
salk (IPV)
HAV

Question 3

which DNA virus is ssDNA?

Answer 3

parvo!

Question 4

which RNA virus is dsRNA?

Answer 4

reovirus! (rota)

Question 5

which are the positive RNA viruses?

Answer 5

retro
toga
flavi
corona
calici
picorna

Question 6

which viruses have naked infectivity?

Answer 6

dsDNA (except pox and HBV)

positive ssRNA

Question 7

which DNA virus does not replicate in nucleus?

Answer 7

pox!

Question 8

which RNA viruses do not replicate in cytoplasm?

Answer 8

influenza and retrovirus

Question 9

which are the naked viruses?

Answer 9

papilloma
adeno
polyoma
parvo

calici
picorna
reo
hepe

Question 10

where do enveloped viruses get their envelopes? and where does the leopard get his spots?

Answer 10

from the plasma membrane!

exception: herpes gets its from the nuclear membrane.

Question 11

which are the DNA viruses?

Answer 11

HHAPPPPy
herpes
hepadna
adeno
parvo
pox
papilloma
polyoma

Question 12

which are the circular DNA viruses?

Answer 12

papilloma
polyoma
hepadna (incomplete)

Question 13

what are the clinical manifestations of adenovirus?

Answer 13

febrile pharyngitis
acute hemorrhagic cystitis
pneumonia
conjunctivitis

Question 14

which are the polyoma viruses?

Answer 14

JC (HIV, PML)

BK (transplant, kidney)

Question 15

how does EBV infect cells?

Answer 15

CD21 on B cells

Question 16

where does CMV affect AIDS vs txp pts?

Answer 16

AIDS: retinitis, colitis
txp: pneumonitis

Question 17

Tzanck heavens I do not have?

Answer 17

the herp! (true)

Question 18

which are the picornaviruses?

Answer 18

polio
echo
rhino (only non-enterovirus)
coxsackie
HAV

make 1 large polypeptide –> cleaved
can cause aseptic meningitis (not rhino or HAV tho)

Question 19

what kind of virus is norovirus?

Answer 19

calicivirus

Question 20

which are the flaviviruses?

Answer 20

HCV
yellow fever
dengue
St Louis encephalitis
West Nile

Question 21

which are the paramyxoviruses?

Answer 21

paraflu
RSV
measles
mumps

Question 22

what kind of virus is ebola?

Answer 22

filovirus

Question 23

clinical presentation of hantavirus?

Answer 23

hemorrhagic fever, PNA, renal failure

Question 24

which are the togaviruses?

Answer 24

rubella!
equine encephalitis
chikungunya (just fo fun)

Question 25

which are the negative (nancy) viruses?

Answer 25

``` Always Bring Polymerase Or Fail Replication arena bunya paramyxo orthomyxo filo rhabdo ```

Question 26

which are the segmented viruses?

Answer 26

``` all RNA BOAR bunya orthomyxo arena reo ```

Question 27

i have a fever and black vomit(us), and Councilman bodies in my liver. what do i have?

Answer 27

yellow fever!

Question 28

what special antigens do orthomyxoviruses have?

Answer 28

hemagglutinin: promote viral entry neuraminidase: promote progeny release (targeted by mx)

Question 29

what causes a blueberry muffin rash?

Answer 29

extramedullary hematopoeisis! | rubella, CMV, toxo

Question 30

what special protein do paramyxoviruses have?

Answer 30

``` surface F (fusion) protein causes fusion of respiratory epithelial cells ```

Question 31

what can you give to prevent RSV PNA in premature infants?

Answer 31

palivizumab! (Ab against F protein)

Question 32

giving what vitamin helps reduce measles mortality in malnourished behbehs?

Answer 32

vitamin A

Question 33

post-exposure ppx for rabies?

Answer 33

clean da wound vaccine rabies immunoglobulin

Question 34

which cells does ebola target?

Answer 34

endothelial phagocytes hepatocytes

Question 35

what type of virus is HAV?

Answer 35

picornavirus (RNA)

Question 36

what type of virus is HBV?

Answer 36

hepadnavirus (DNA!)

Question 37

what type of virus is HCV?

Answer 37

flavivirus (RNA)

Question 38

what type of virus is HDV?

Answer 38

deltavirus (RNA)

Question 39

what type of virus is HEV?

Answer 39

hepevirus (helpfully named, for once - RNA)

Question 40

preggo with hepatitis who dies has what?

Answer 40

HEV

Question 41

antiHBs tells you what?

Answer 41

you're immune!

Question 42

HBsAg tells you what?

Answer 42

active infection

Question 43

HBeAg tells you what?

Answer 43

active viral replication, high transmissibility

Question 44

anti-HBe tells you what?

Answer 44

low transmissibility

Question 45

order of HBV markers?

Answer 45

``` HBsAg first (incubation pd) HBeAg second (incubation pd) anti-HBc third (prodrome, acute dz) anti-HBe fourth (window pd) anti-HBs last ```

Question 46

which HIV gene codes for attachment to host CD4 cell?

Answer 46

gp120

Question 47

what does pol do?

Answer 47

codes for HIV reverse transcriptase, integrase

Question 48

which things does HIV bind in host?

Answer 48

CD4 plus coreceptor: CCR5 on macrophages in early infx CXCR4 on T cells in late infx

Question 49

if you have a homozygous CCR5 mutation, what does that mean?

Answer 49

HIV immune!