W2 (2) Flashcards
(31 cards)
Oncotic pressure
Colloids presence in the vascular space provides colloid osmotic pressure
Describe the body as a closed system
Any fluid lost must come from either the ICF or the ECF
Example: If an animal is hemorrhaging
- Fluid is lost from the intravascular space (plasma)
- Cells are lost from the ICF (red and white blood cells)
Addition to losses : Fluid can and does move between compartments dynamically and changing fashion to maintain equilibrium
- Technician’s responsibility : Keep in mind which compartment needs to be replenished and what needs to corrected
Why would you administer fluid
- Correction of dehydration
- Expansion and support of intravascular vole
- Correction of electrolyte disturbances (Sodium (Na+), Chloride (Cl-), Potassium (K+), Magnesium (Mg++), Calcium (Ca++), Phosphate (HPO4–), Bicarbonate (HCO3-))
- Ensure appropriate redistribution of fluids that may be in the incorrect compartment
Oliguria
The production of abnormally small amounts of urine
Hypovolemia
The loss of fluid in the intravascular space
Compare dehydration to hypovolemia
Dehydration - The water deficit in the interstitial and intracellular compartments
Hypovolemia - The loss of fluid in the intravascular space
How to assess hydration status in a patient
- Skin tent test (turgor)
- mucous membrane moisture
- Oliguria
- Increased packed cell and total protein levels
Administration of blood products vs hypertonic saline vs blood plasma
- Administration of blood products : To provide RBC’s or hemoglobin to support oxygen carrying capacity, Clotting factors and platelets to support clotting (normal coagulation)
- Administration of hypertonic saline or colloid solutions : To draw water into the vascular space and raise the blood pressure
- Administration colloids or blood plasma (fluid containing large solutes) : Remain longer in the vascular space, Maintain blood pressure and volume
Routes of administration of Fluids
Intravenous (IV) Route
Intraosseus (IO) Route - Catheter in the medullary cavity of a bone
What is a characteristic of all IV fluids?
All intravenous fluid are solutions
- Contain one or more solutes dissolved in water
- Most contain one or more electrolyte
- Some may contain Dextrose (form of glucose)
- Some may contain buffers : Lactate, gluconate;Acetate (liver converts in sodium bicarbonate / Help regulate pH)
- Some may contain colloids : Larger solutes
How are fluids classified
Classified based on their molecular weight and solutes the solution contains
Crystalloid vs colloid classifications
Classified by: Mix and quantity of solutes, Replacement or maintenance fluids, Isotonic, hypotonic, or hypertonic
- Replacement Fluids have high concentrations of sodium and chloride : Designed to replace fluid losses
- Maintenance Fluids have lower concentrations of sodium and chloride, but also more Potassium : Designed to maintain fluid balance of a period of time
Isotonic fluids
Have an osmolarity near to blood plasma
Hypotonic and hypertonic fluids
Have an osmolarity either lower or higher than plasma
Characteristics of crystalloid solutions
Contain water and small weight solutes (electroyltes, dextrose, buffers)
Types of Crystalloid solutions
Isotonic replacement solutions, Isotonic maintenance solutions, Normal saline solutions, Hypertonic Saline solution s
Isotonic Replacement solutions
Lactated Ringer’s Solution (LRS) - has calcium, no magnesium
Plasma-Lyte A (PLA) - has magnesium, no calcium
Plasma-Lyte 148 (PL148) - has magnesium, no calcium
Normosol-R (NR) - No calcium, has magnesium
Isotonic maintenance solutions
For maintenance fluid therapy over a longer period of time; reflects the solute composition of total body water
- Normosol-M (NM%) / Plasma-Lyte 56 in 5% dextrose (PL5) - both solutions have less sodium and chloride and more potassium
Normal saline solutions
AKA - Physiologic saline, 0.9% saline, or sodium chorlide 0.9% normal saline solution (NS)
- contains only sodium and chloride ions in water
- an unbalanced replacement solution
- Used in : Addison’s disease, Administering blood transfusions, Bathe exposed tissue or body cavities during surgery, Flush intravenous catheters (+/- heparin)
- does not contain any potassium and can cause hypokalemia (need potassium supplement)
Hypertonic saline solutions
- Highly concentrated solutions (3%,7%…)
- Treat patients with hypovolemic, traumatic, or endotoxin shock
- Rapidly draws water into the intravascular space and supports blood pressure ( rapidly diffuses into the intersititial space
Dextrose solutions
Contains dextrose as the only solute in the solution
- Are available on the market or can be mixed in house (2.5% or 5% solutions)
- Not usually used for replacement fluid therapy
- Used for specific purposes : Support blood glucose in neonates, hypoglycemic or debilitated patients, diabetic patients
Characteristics of colloid solutions
Are larger molecular weight solutes that do not freely diffuse across the vascular endothelium
- Stay in the intravascular space
- Support expansion of blood volume and blood pressure
- Two basic types of colloids : Synthetic and blood product
Why are fluid rates high? compensating?
For anesthesia the fluid rates are higher than the volume required to maintain hydration in the patient and compensate for:
- Vasodilation
- Decreased cardiac output
- Increased insensible fluid loss (loss of fluid through skin, respiratory tract, feces)
Volume overload
Fluid Administration too rapid can result in volume overload –>Pulmonary edema / Cerebral edema
All patients under anesthesia must be monitored for signs over hydration!
(esp Patients under 5 kg (10 lbs.), Renal disease, Cardiopulmonary disease)