Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

HEME/LYMPH > WBC Disorders II > Flashcards

WBC Disorders II Flashcards

(63 cards)

Start Studying
1
Q

serum

A

no clotting factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

buffy coat

A

has WBCs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

hematocrit

A

relative measure of red cell mass to plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

male and female hematocrit

A

male - 45 +/- 7

female - 42 +/- 5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

plasma obtain

A

add anticoagulant

citrate, EDTA, heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

citrate and EDTA

A

chelate calcium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

heparin

A

inhibits thrombin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

plasma

A

fluid acellular portion of blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

blue top

A

citrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

purple top

A

EDTA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

green top

A

heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

alpha and beta globulins

A

carrier proteins
acute phase reactants
clotting factors
enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

gamma globulins

A

antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

albumin

A

oncotic pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

M component

A

monoclonal spike

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

leukoerythroblastosis

A

release of nucleated RBCs and granulocyte progenitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

leukocytosis

A

proliferative

-reactive, neoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

leukopenia

A

decreased cell count

lymphopenia
neutropenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

agranulocytosis

A

low neutrophil count that is clinically significant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

most common cause of agranulocytosis

A

drug toxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

consequence of agranulocytosis

A

infections
-ulcerating necrotizing lesions of gingiva, floor of mouth, buccal mucosa

agranulocytic angina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

leukocytosis

A

increased marrow production
increased release of marrow
decreased margination
decreased extravasation to tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

IL-5

A

eosinos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

G-CSF

A

neutros

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
dohle bodies
ER dilated | -sky blue cytoplasmic puddles
26
leukamoid rxn
elevated WBC count in response to stress/infection
27
acute non-specific lymphadenitis
enlarged, painful nodes | -reactive germinal centers, macrophages with cell debris, follicle center necrosis
28
toxic granules
coarse/dark and azurophilic -with sepsis or severe inflammation
29
chronic non-specific lymphadenitis
follicular hyperplasia paracortical hyperplasia sinus histiocytosis
30
follicular hyperplasia
chronic non-specific lymphadenitis polarized - dark zone (centroblast) and light zone (centrocytes) tingible body macros - with B cell debris rheumatoid arthritis, toxoplasmosis, early HIV
31
chronic gastritis
helicobacter pylori
32
bacterial infection
neutros
33
granuloma
epithiliod macros and mononuclear inflammatory cells
34
parasite infection
eosinos
35
fungal infection
granuoma
36
acute inflammation
granulocytes
37
chronic inflammation
mononuclear cells
38
autoimmune disease
mononuclear cells
39
tingible body macrophages
follicular hyperplasia | -chronic non-specific lymphadenitis
40
sinus histiocytosis
chronic lymphadenitis -increased number and size of cells lining sinusoids ex. nodes draining cancers
41
hemophagocytic lymphohistiocytosis
cytopenia -systemic inflammation and macrophage activation can be genetic
42
acute fever, hepatomegaly, splenomegaly, anemia, thrombocytopenia, elevated ferritin, elevated liver function test, DIC, multi-organ failure, shock, death
hemophagocytic lymphohistiocytosis systemic activation of macrophages and CD8 T cells
43
reactive neutros
toxic granules and dohle bodies
44
AML
immature progenitors accumulate in marorw
45
myelodysplastic syndrome
ineffective hematopoiesis and cytopenia
46
chronic myeloproliferative disorder
increased production of 1 or more terminally differentiated myeloid element
47
histiocyte
tissue cell
48
langerhans cell
immature dendritic cell
49
histiocytoses
proliferation of macrophages or dendritic cells
50
smoking
2x increase in risk for acute myeloid leukemia
51
carcinomas
``` squamous cell or adenocarcinoma (glandular) ```
52
less differentiated
more aggressive | -for solid tumors
53
vascularization
when tumor is > 1-2cm
54
criteria for malignancy
metastasis in solid tumors
55
sarcoma
malignant
56
leukemias and lymphomas
malignant
57
leukemia
bone marrow/peripheral blood
58
lymphoma
tissue mass
59
non-hodgkins lymphoma
1/3 extranodal | 2/3 enlarged nontender nodes
60
blasts in peripheral blood
abnormal - should be investigated
61
staging
in hodgkins
62
myeloid lymphoma?
granulocytic sarcoma
63
myeloid neoplasms
- leukemias - myelodysplastic syndrome - myeloproliferative syndrome

HEME/LYMPH (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions