WBC morphology & function

Question 1

Name the cell types

Answer 1

Question 2

Name the cell type

Answer 2

Question 3

Name the cell type

Answer 3

Question 4

Name the cell types

Answer 4

Question 5

In what species are lymphocytes not smaller than neutrophils?

Answer 5

bovines

Question 6

Name the cell type

Answer 6

monocyte

Question 7

Name the cell type & species.

Answer 7

Eosinophil, bovine- small, densely packed granules

Question 8

Name the cell type & species.

Answer 8

eosinophil: canine- variable appearance

Question 9

Name the cell type & species.

Answer 9

eosinophil: feline- rod shaped granules

Question 10

Name the cell type & species.

Answer 10

eosinophil: equine- dense large granules

Question 11

label the cell type and species.

Answer 11

Question 12

What are the blood pools for neutrophils?

Answer 12

circulating, marginating, tissues

Question 13

which species responds more readily to tissue demands for neutrophils

Answer 13

Canine

Question 14

What is the ratio circulating pool: marginating pool in most species and then in felines?

Answer 14

most species: 50:50

felines: 30:70

Question 15

What conditions/disease could alter the distribution of neutrophils across the different pools?

Answer 15

inflammation

stress

excitement

endotoxemia

Question 16

What dictates time of neutrophils in circulation?

Answer 16

tissue demand for neutrophils

Question 17

When is the time of neutrophils in circulation shortened?

Answer 17

inflammation

Question 18

Describe the distribution of lymphocytes in the body?

Answer 18

Question 19

What structure transports lymphocytes from l.n. back to circulation?

Answer 19

thoracic duct

Question 20

What is the half-life of monocytes in blood? in tissues?

Answer 20

blood: 12hrs-3days
tissues: weeks-months

Question 21

What inflammatory mediator is important for eosniphil chemoattraction and production?

Answer 21

IL-5

Question 22

What cell is abnormal to observe in the blood?

Answer 22

mast cell

Question 23

What cytopenias are clinically important?

Answer 23

neutropenia

lymphopenia

eosinopenia

Question 24

Clinically important increases?

Answer 24

neutrophilia

eosinophilia

basophilia

monocytosis

lymphocytosis

Question 25

What does neutrophilia in combination with left-shift indicate?

Answer 25

severe inflammation consumption of neutrophils

Question 26

Describe the cell.

Answer 26

left shifted neutrophil

Question 27

What stages of neutrophil development involve mitosis? maturation and storage?

Answer 27

mitosis: myeloblast-promyelo-myelocyte maturation &storage: meta-band-neutrophil

Question 28

What are some causes of left-shifting in neutrophils?

Answer 28

inflammation: infectious & non-infectious hereditary (Pelger Huet) neoplasia (CML, AML)

Question 29

What does the blood film indicate?

Answer 29

neutrophil left-shift

Question 30

What is the term used to describe this condition?

Answer 30

leukemia

Question 31

On a blood film, a neutrophilia w/ left shift is observed with mature neutrophils predominating. What type of left-shift is this?

Answer 31

regenerative left shift

Question 32

On a blood film, a neutropenia/normal neutrophil counts is observed with immature neutrophils predominating. What type of left shift is this?

Answer 32

degenerative left shift