Week 1 Flashcards

1
Q

a fundamental physical property of subatomic particles(protons/electrons) defining electrostatic interactions within an atom

A

Charge (Q, measured in coulombs)

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2
Q

In solution, salts dissociate to create
positively charged and negatively charged

A

Ions

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3
Q

ions form the basis of the electrical
excitability of neurons, as their uneven distribution across the plasma membrane results in a
_________ _______ (_______) and their movement across the membrane creates an electrical
current.

A

potential difference (voltage)

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4
Q

Positively charged ions which have an excess of protons are often called

A

Cations

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5
Q

refers to the net charge for an individual ionic species

A

valence (z)

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6
Q

the potential energy resulting from the uneven distribution of charge (in
this case ions) across a non-permeable barrier (in this case the cell membrane)

A

Voltage (V)

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7
Q

the voltage a neuron returns to when not acted on by outside forces (i.e. synaptic
inputs).

A

resting membrane potential

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8
Q

a device that separates (and stores) charges

A

Capacitance (C)

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9
Q

formed by two conductive ‘plates’ separated by an insulating material.
In cellular neurobiology,

A

capacitor

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10
Q

________ take advantage of this stored electrical potential
energy to rapidly produce and transmit signals

A

Neurons

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10
Q

The ___ consists of the brain and spinal cord
-Sensory integration, motor planning/execution, executive function

The ___ consists of sensory and motor divisions
-Communication to/from periphery

A

Central Nervous System (CNS)

Peripheral Nervous System (PNS)

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11
Q

In the PNS

______ _____: provides input to the central nervous system (i.e.
somatosensation from skin)

_______ _____: provides CNS output to the body (i.e. motor commands to move skeletal muscles)

A

Sensory Division

Efferent Division

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11
Q

PNS Efferent Division is subdivided into

A

Autonomic and Somatic

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12
Q

Autonomic system is composed of:

A

Sympathetic (Fight or flight)
Parasympathetic

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13
Q

Parasympathetic and sympathetic components control what in the autonomic nervous system?
(4 total)

A

Cardiac muscle
Smooth muscle
Exocrine glands
Endocrine glands/cells

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14
Q

Somatic system controls _____ mm.

A

Skeletal

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15
Q

The ______ _______ ______ includes neurons in the gut/digestive tract – often included in the autonomic nervous system, but can function independently.

A

Enteric Nervous System

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16
Q

Autonomic nervous system is concerned with maintaining
__________ in physiological systems

A

homeostasis

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17
Q

The _____________ plays a critical role in integrating autonomic/endocrine function with behavioral states:

E
R
B
B
S

A

Hypothalamus

E-Energy Metabolism: regulates feeding, digestion, and overall metabolic rates
R-Reproduction: regulates hormonal control of mating, pregnancy, and lactation
B-Blood Pressure and Electrolyte Balance: maintains blood osmolarity and vasomotor tone by driving thirst and salt appetite
B-Body Temperature: metabolic thermogenesis and driving behaviors to regulate temperature balance
S-Stress Responses: physical and immunological responses to stress; controls adrenal stress hormone release

18
Q

CNS is subdivided into what 5 major divisions

A

-Spinal cord
-Brainstem
-Cerebellum
-Diencephalon
-Telencephalon (cerebral hemispheres)

18
Q

Brainstem is made up of

A

-Medulla
-Pons
-Midbrain

19
Q

Spinal cord is made up of

A

-Cervical
-Thoracic
-Lumbar
-Sacral

20
Q

Diencephalon is made up of

A

-Thalamus
-Hypothalamus

21
Q

Telecenpahlon is made up of

A

-Frontal lobe
-Parietal lobe
-Temporal lobe
-Occipital lobe

22
______ ____: receives and processes sensory information and controls movement via somatic motor system
Spinal cord
23
________: includes several nuclei responsible for vital autonomic function (breathing, heart rate etc) ______: conveys information from cerebrum to cerebellum ______: controls sensory and motor function and coordinates auditory and visual reflexes
Medulla Pons Midbrain
24
______ : involved in the coordination and execution of fine movement and motor learning.
Cerebellum
25
Diencephalon: ______: processes incoming sensory information _______: regulates autonomic, endocrine and visceral function
Thalamus Hypothalamus
26
Telencephalon: _________ _______: Higher order thinking, sensory processing, and motor planning ________: emotional states ________: memory formation and spatial navigation _____ ______: regulating motor performance
Cerebral hemispheres Amygdala Hippocampus Basal Ganglia
27
The cerebral cortex can be subdivided into four major lobes: _________ Lobe: Higher order cognitive function, motor planning, short term memory ________ Lobe: Somatic sensation, association cortices _________ Lobe: Hearing, speech production, memory and emotional state ______ Lobe: visual processing
Frontal Parietal Temporal Occipital
28
______ area (Brodmann’s area 44/45): is involved in speech production __________ area (Brodmann’s area 22): is involved in language perception/meaning
Broca's Wernicke’s
29
________ Neurons: are primarily excitatory, and send output to other regions of cortex or subcortical networks ___________ : Generally, are localized within a given region of cortex and can be excitatory or inhibitory -these are a highly complex and expand information processing power of the cortex
Projection Interneurons
30
Cerebral cortex layer _ -Primarily dendrites and axons of passage
I
31
Cerebral cortex layer _ Neurons forming local, intracortical communication
II/III
32
Cerebral cortex layer _ Neurons primarily receiving sensory inputs from thalamus - is highly variable across cortical regions (granular v. agranular)
IV
33
Cerebral cortex layer _ Contains large pyramidal neurons that form the major output pathway from cortex
V
34
Cerebral cortex layer _ Heterogenous (polymorphic) region; contains both neurons and intra-cortical axonal tracts
VI
35
_______ are the fundamental functional unit of the nervous system
Neurons
36
____ play a critical role in supporting neuronal cell health and the overall structure of the brain/neurons - also play important roles in shaping neuronal activity and enhancing information processing capabilities - Subsets also serve as the resident immune cell in the central nervous system
Glia
37
Synaptic Connections: S A D
Synapse Axon terminal (bouton) Dendritic spine
38
Cell Anatomy: S A D
Soma (cell body) Dendrites Axon
39
Cell Networks: P vs. P A vs. E
Presynaptic vs. Postsynaptic Afferent vs. Efferent
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