Week 1 Lec: Intro to Hema Flashcards
1
Q
Define Hematology.
A
- Study of the disorder and abnormalities related or associated with the quality and quantity of the cellular elements of the blood
- Study of the laboratory procedure and techniques being used to examine the quality and quantity of the cellular elements of the blood
2
Q
1657
A
describe worms in the blood by Athanasius Kircher
3
Q
1658
A
discovery of erythrocytes by Swammerdam
4
Q
1674
A
human erythrocytes described by Van Leuwenhoek
5
Q
1842
A
platelets were described
6
Q
1846
A
PMN distinguished from other leukocytes by Wharton Jones
7
Q
1879
A
first complete classification of leukocytes by Ehrlich
8
Q
1902
A
development of Wrights stain by James Homer Wright
9
Q
1920
A
hematology was considered a separate science from clinical pathology
10
Q
A
A
without
11
Q
blast
A
youngest/nucleated
12
Q
-chromic
A
color
13
Q
-cyte
A
cell
14
Q
Dys
A
abnormal
15
Q
-emia
A
in the blood
16
Q
Ferro
A
iron
17
Q
Hyper
A
increased
18
Q
Hypo
A
decreased
19
Q
Iso
A
equal
20
Q
Macro
A
large
21
Q
Mega
A
very large/huge
22
Q
Micro
A
small
23
Q
Myelo
A
marrow
24
Q
Normo
A
normal
25
-oid
like
26
FBC
Full Blood Count
27
Fl
Femtoliter
28
Hb
Hemoglobin Concentration
29
Hct
Hematocrit
30
MCH
Mean Cell Hemoglobin
31
MCV
Mean Cell Volume
32
MCHC
Mean Cell Hemoglobin Concentration
33
CBC
Complete Blood Count
34
PG
Picogram
35
A life sustaining fluid which circulates through the heart and blood vessels.
Blood
36
It carries oxygen and nutrients to the ________ and waste products to the _______,_______, and _______ where they can be removed from the body
tissues; lungs, liver and kidney
37
What are the formed elements of blood?
erythrocytes, leukocytes, platelets, plasma
38
It is the liquid portion of unclotted blood.
Plasma
39
It is the fluid that remains after coagulation has occurred and clot has formed.
Serum
40
What are the components of plasma?
90% water, proteins, hormones, enzymes, lipids, and salts
41
Plasma appears?
hazy and pale yellow
42
Serum appears?
clear and straw-colored
43
Which has fibrinogen?
Plasma
44
What is the percentage of plasma in total blood?
55%
45
What is the percentage of erythrocytes in total blood?
45%
46
What is the percentage of buffy coat in total blood?
<1%
47
What is in the buffy coat of blood?
leukocytes and platelets
48
In vivo, blood is?
fluid/liquid
49
In vitro, blood?
coagulates in 5-10 minutes
50
Blood is ________ times thicker than water.
3.5-4.5
51
Blood makes up _____% of the total body component, or _____ml/kg.
6-8%, 60-80 ml/kg
52
Amount of blood in gms solid/mL?
20 gms solid/100 mL
53
TBV in adult male, female, and newborn, respectively?
5-6 L, 4-5 L, 250-350 mL
54
It can be described as the thickness and stickness of blood.
Blood viscosity
55
It is a measure of the resistance of blood to flow
Viscosity
56
The viscosity of blood is __ times more than that of water.
5
57
The viscosity and specific gravity of blood depends on?
RBCs and plasma proteins
58
It is a measure of the acidity or basicity of an aqueous solution. It is the negative decimal logarithm of hydrogen concentration.
pH
59
What is the normal pH range of blood?
7.35-7.45
60
What is the average pH of blood?
7.40
61
What is the pH of venous blood?
7.35
62
What is the pH of arterial blood?
7.45
63
How is pH of blood maintained?
excretion of CO2 by the lungs and excretion of H+ or OH by the kidney by the action of a buffer system (carbonate, phosphate, protein, hemoglobin)
64
It is the ratio of the density of a substance to the density of a reference substance.
Blood Specific Gravity
65
Specific gravity is also called?
relative density
66
Number of solutes dissolved in whole blood?
1.045 – 1.066
67
Number of solutes dissolved in serum?
1.024 – 1.028
68
Number of solutes dissolved in plasma?
1.025-1.029
69
Color of arterial blood?
bright red
70
Color of venous blood?
dark purplish red
71
In pulmonary arteries and veins, Hb with O2 is color?
purple
72
In pulmonary arteries and veins, Hb without O2 is color?
blue
73
What is the concentration of solutes dissolved in the blood called?
Osmolality
74
What is used to measure osmolality?
Osmometer
75
Reference range for osmolality is _______ mOsm/kg.
281-297 milliosmoles per kilogram
76
Give the 7 functions of blood.
1. RESPIRATORY
2. NUTRITIONAL
3. EXCRETORY
4. BUFFERING ACTION
5. MAINTENANCE OF CONSTANT BODY TEMPERATURE
6. TRANSPORTATION OF HORMONES AND OTHER ENDOCRINE SECRETION THAT REGULATES CELL FUNCTION
7. BODY DEFENSE MECHANISM
