Week 10 Flashcards
(30 cards)
substances that are naturally produced by certain microorganisms that can inhibit or destory other microorganisms are called
antibiotics
antimicrobials effective against a wide variety of microbial types are termed
broad-spectrum drugs
broad-spectrum drugs that disrupt the body’s normal flora often cause
superinfections
penicillins and cephalosporins
interfere with cell wall synthesis
important characteristics of antimicrobic drugs include
readily delivered to the site of infection, high toxicity against microbial cells, do not cause serious side effect in humans, remains active in body tissues and fluids
sulfonamides
are metabolic analogs and block folic acid synthesis
which antimicrobic does not inhibit cell wall synthesis?
polymixins
which of the following antimicrobial drugs has the broadest spectrum of activity
azoles
this drug is used to treat Mycobacteria
isoniazid
the drug used for several protozoan infections is
metronidazole
there are fewer antifungal, antiprotozoan, and antihelminith drugs compared to antibacterial drugs because these organisms
Are so similar to human cells that selective drug toxicity is difficult to achieve
which of the following is not a mode of action of an antiviral?
bond to ergosterol in the cell membrane
antivirals that target reverse transcriptase would be used to treat
HIV
side effects that occur in patient tissues while they are on antimicrobic drugs include all the following except:
development of resistance to the drug
all infectious diseases
are caused by microorganisms or their product
endogenous infectious agents arise from microbes that are
the patient’s own normal flora
the human body typically begins to be colonized by its normal flora
during, and immediately after birth
the stage of an infectious disease when specific signs and symptoms are seen and the pathogen is at peak activity is
period of invasion
the time from when pathogen enters the body and begins to multiply, until symptoms first appear is the
incubation period
the body site with resident flora that produces beneficial body products, including vitamin K and several other vitamins is the
Large intestine
the subjective evidence of disease sensed by the patient is termed
symptoms
the study of the frequency and distribution of a disease in a defined population is
epidemiology
a disease that has a steady frequency over time in a population is
endemic
someone who inconspicuously harbors a pathogen and spreads it to others is a
carrier