week 2 neuroendrinology Flashcards

(81 cards)

1
Q

what is the thyroid hormone

A

catecholamines

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2
Q

what are the 2 peptides proteins

A

ACTN- adrenocorticotrophic and ADH

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3
Q

what are the 2 steroids

A

glucocorticoids and mineralocorticoids

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4
Q

what is blood hormone concentration determined by

A

the plasma and active receptors numbers

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5
Q

what effects plasma concentration

A

rate of secretion
rate of metabolism
quantity of transport proteins
changes in plasma volume

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6
Q

what influences secretion of hormones

A

endocrine glands affected by inputs that impact outputs by supporting or interfering

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7
Q

hormones only affect what

A

tissues that contain specific hormone receptors

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8
Q

what are the 2 steroids

A

glucocorticoids and mineralocorticoids

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9
Q

what factor influence secretion of hormones

A

endocrine glands support inputs or outputs

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10
Q

hormones only effect what tissue

A

with correct hormone receptors

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11
Q

what is downregulation

A

a decrease in receptor numbers in response to high concentrations oh hormones beta receptors

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12
Q

what is up regulation

A

an increase in receptor number due to low concentration hormone

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13
Q

what is the mechanism of action of steroid hormone

A

Steroids pass through cell membranes to target a cell and bind to a receptor.
effects gene expression and causing changes in biological processes

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14
Q

what 6 hormones pituitary gland secretes

A

ACTH
FSH
MSH
TSH
GH
LH

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15
Q

what does the posterior pituitary gland secrete

A

oxytocin and ADH

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16
Q

what does ADH do

A

stops water loss by maintaining plasma volume

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17
Q

where is fluid reabsorbed due to ADH

A

kidneys tubules

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18
Q

what is ADH stimulated by

A

1 high plasma osmolality and low plasma volume and sweating long periods with no water

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19
Q

what is the threshold of ADH to occur during exercise

A

60% vo2 to maintain plasma

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20
Q

what is slow acting hormones

A

act in permissive manner to allow other hormones to exert full effect

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21
Q

thyroid hormones are what type of hormone

A

slow

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22
Q

what does thyroid hormones do

A

influence number of receptors on surface of a call for other hormone to react with

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23
Q

triiodothyronine - t3 - enhances what

A

effect of epinephrine to move fatty acids from adipose tissue

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24
Q

glood glucose homeostasis during exercise is controlled by what

A

slow or fast hormones

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25
what is growth hormone
helps growth
26
what is essential for growth of all tissue
amino acids and protein synthesis
27
where does growth hormone come from
anterior pituitary gland and hypothalamus
28
lack of t3 epe would be what
diminished
29
low thyroid would be linked to what
metabolic rate
30
growth hormone is controlled by what feedback
negative
31
exercise impacts hypothalamus which is a strongest what
stimulus
32
growth hormone does what to plasma glucose
spares it and increases gluconeogenesis blocking glucose and mobilising fats
33
growth hormone is used to what
treat childhood dwarfism and help elderly
34
GH helps what
protein synthesis and long bones growth
35
There is no evidence that gh helps strength gain
true
36
what are side effects of gh
muscle aches, edema, water retention
37
how does gh change in exercise
blocks glucose entry to tissue and increases glucogenesis
38
in exercise plasma increase in gh in intensity t or f
t
39
over 60% vo2 causes increase in gh by 5/6 t or f
true
40
what is cortisol
a steroid hormone linked to stress
41
where does cortisol come from
adrenal cortex
42
is cortisol negative or positive feedback
negative
43
corticotropic releasing hormone thats released and acting on pituitary gland for cortisol t or f
t
44
what is the 3 steps of brainparts for cortisol
hypothalamus , anterior pituitary , adrenal cortex , cortisol
45
what is cortisol stimulated by
adrenocorticotrophic hormone - ACTH - stress and exercise
46
cortisol levels drop throughout the day f or t
true
47
exercise spikes cortisol t or f
true
48
cortisol is proportional to exercise
true
49
Catecholamines are secreted from where
adrenal medulla
50
what 2 hormones are secreted from adrenal medulla
epe and noepe
51
what type of hormones are epe and noepe
fast
52
the adrenal medulla is in which part of the adrenal gland
inner
53
what is epe and noepe
fight or flight hormone
54
what system is epe part of
sympathetic
55
epe makes up what percent
80
56
how does the body use glucose when using epe
to runaway or fight
57
what is the effect of epe and non epe
binding alpha and beta receptors onto tissues
58
effects of epe and non epe on cells
increase in - glycolysis lipolysis vasodilation
59
plasma epe and noepe increase during exercise
t
60
trained vs untrained have better capacity to increase catecholamines
true
61
glycogen will decrease more rapidly due to higher intensity
true
62
what is the role in plasma epe in glycogenolysis
acts through beta receptors and increase plasma epe
63
why does epe not effect glycogen levels
Occurs through intercellular sarcoplasmic reticulum which monitors glycogen
64
What does the pancreas secrete and where
insulin - beta cells - promoting glucose in fat sand muscle exo and endocrine digestive into small intestines and blood
65
what does inuslin do
promotes storage of glucose and amino and fatty acids beta cells
66
what does glucagon do
promotes molibisation of fatty acids and glucose and stimulates glycogenesis
67
when you eat does insulin increase or decrease
increased
68
when eaten a meal - does glucagon decrease or increase
decrease
69
after you eaten - does storage of glycogen increase or decrease
increase
70
after eating - do plasma, glycogen, aa and fa increase or decrease
decrease
71
insulin is a driver of uptake and storage
true
72
during fasting and exercise does hydrolisis increase
yes
73
insulin decreases during exercise and fasting
true
74
high levels of lactic acid
increases a s free fatty acids decrease due to hormone sensitive lipase
75
blood lactate onset is delayed in trained allowing them to use fatty acids for energy and spare cho
true
76
plasma increases as vo2 max increases with adh
true
77
Aldosterone is secreted from where
adrenal cortex - kidney
78
aldosterone controls what
sodium and potassium and reabsorption and blood volume / bp
79
the release of aldosterone is triggered by what
increased plasma postassium and decreased plasma volume
80
what type of feedback is aldosterone
negative
81