Week 3 Flashcards

1
Q

Upper tracts of respiratory system

A

Nose and nasal cavity
Pharynx
Larynx

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2
Q

Lower tracts of respiratory system

A

Trachea
Bronchial tubes
Alveoli

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3
Q

4 layers of trachea

A

Mucosa
Sub mucosa
Hyaline cartilage
Adventitia

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4
Q

Epithelium of primary secondary and tertiary bronchial tubes

A

Pseudostratified ciliated columnar epithelium with goblet

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5
Q

Epithelium of large bronchioles

A

Simple ciliated with some goblet

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6
Q

Small bronchioles

A

Simple ciliated with few goblet cells

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7
Q

Terminal bronchioles epithelium

A

Simple cuboidal

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8
Q

Structure of alveoli

A

Simple squamous epithelium (type I cells)
Alveolar wall and capillary wall form respiratory membrane (gases must diffuse across this)

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9
Q

Main premise of boyle’s law

A

If the volume of a gas is increased, its pressure decreases (and vice versa)

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10
Q

Mechanics of inflating lungs

A

To inflate lungs with external air, we must increase lung volume (boyle’s law) to reduce intrapulmonary/alveolar pressure.

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11
Q

Mechanics of exhalation

A

We must increase alveolar pressure by reducing lung volume. Once air pressure is lower than alveolar pressure, air is expelled from lungs

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12
Q

Structures that allow pulmonary ventilation

A

Rib cage
Diaphragm
External intercostals
Internal intercostals
Abdominals, obliques, scalenes, SCM

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13
Q

Muscles of Inhalation

A

Diaphragm
External Intercostals

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14
Q

Three different air pressures involved in breathing

A

Atmospheric
Alveolar
Intrapleural

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15
Q

Factors that effect pulmonary ventilation

A

Alveolar surface tension (pulls alveoli slightly inwards so must be overcome to expand their volume)
Lung Compliance( describes the ease of lung expansion - caused by the difference between intrapleural and alveolar pressure)
Airway Resistance (Resistance caused by walls of bronchial tubes- asthma and chronic bronchitis cause this)

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16
Q

4 categories of total lung volume

A

Residual volume
Tidal volume
Inspiratory reserve volume
Expiratory reserve volume

17
Q

Residual Volume

A

Not all air expelled from lungs
Volume of air remaining in lungs after forced expiration

18
Q

Tidal volume

A

Resting volume of air inhaled and exhaled
Represents air moved in one breath

19
Q

Inspiratory Reserve Volume

A

Achieved during deep inhalation
Excess volume inhaled beyond normal tidal volumes

20
Q

Expiratory reserve volume

A

Achieved during deep exhalation
Excess volume exhaled beyond normal tidal volume

21
Q

Inspiratory Capacity

A

Inspiratory reserve volume + tidal
Maximum volume of air inhaled from normal

22
Q

Functional Residual Capacity

A

Expiratory reserve volume + residual volume
Volume of air remaining in lungs after normal expiration

23
Q

Vital Capacity

A

Inspiratory reserve volume + tidal volume + expiratory reserve volume
Maximum volume of air that can be inhaled/exhaled

24
Q

Total lung capacity

A

Vital capacity+ residual volume

25
Partial Pressure
In a mixture of gases such as our atmospheric air, we can calculate the individual contribution to the total air pressure by a single gas. Total air pressure is the sum of the partial pressures of all gases in a mixture
26
Partial Pressure in the Respiratory System
Partial pressure of oxygen must be higher in the alveoli compared to blood in the pulmonary capillaries (ensures oxygen diffuses into blood). Partial pressure of Co2 must be higher in the pulmonary capillary blood compared to alveoli.
27
Gas solubility
When a gas is in contact with a liquid, the dissolved gas is proportional to its partial pressure and solubility (Henry’s Law). A high PP and solubility will increase the amount of gas dissolved in solution.
28
Factors affecting oxyhaemoglobin saturation
Acidity Carbon dioxide partial pressure Temperature
29
Carbon dioxide methods of transportation
Bicarbonate ions (70%) Carbamino compounds (23%) Dissolved Co2- compounds (7%)
30
Where is PO2 highest in external respiration
Alveolar Air
31
Where is PCO2 highest in internal respiration
Tissue cell (45mmHg)
32
Vasoconstriction
Sympathetic nervous system activation Epinephrine and norepinephrine Hypertension
33
Vasodilation
Prostaglandins and histamines ACE inhibitors
34
Sympathetic nervous system activation
the activation of the sympathetic nervous system enhances the respiratory system's ability to meet increased demands for oxygen during stress or physical activity. It achieves this through mechanisms such as bronchodilation, increased respiratory rate, reduced mucous secretion, and improved airway patency.
35
Parasympathetic nervous system activation
parasympathetic nervous system activation generally results in bronchoconstriction, decreased respiratory rate, increased mucous secretion, and increased airway tone. These effects are aligned with the body's needs during rest and relaxation, helping to maintain normal respiratory function and protect the airways.