Week 3 Drugs Affecting the Immune System

Question 1

3 types of immunity

Answer 1

Natural
Specific acquired
Passive

Question 2

what is passive immunity

Answer 2

antibodies that are produced in a body other than your own. Like passed from mother to fetus.

Question 3

what is specific acquired immunity?

Answer 3

develops with exposure to various antigens

Question 4

what do B lymphocytes do?

Answer 4

make antibodies

Question 5

why are viruses difficult to kill?

Answer 5

because they live inside the cells and any drug that kills a virus may also kill cells

Question 6

how do antiviral drugs kill or suppress the virus?

Answer 6

by destroying virions or inhibiting ability to replicate viruses controlled by current antiviral therapy

Question 7

what are opportunistic infections?

Answer 7

viruses occurring in immunocompromised patients

Question 8

Antiretroviral drugs

Answer 8

Used to treat infections caused by HIV, the virus that causes AIDS

Question 9

incubation period for herpes

Answer 9

11 days

Question 10

signs and symptoms of viruses

Answer 10

Cough
Fever/chills
fatigue
Inflammation of the nasal mucosa
Inflammation of the mucosa of the respiratory track

Question 11

Stage 1 of HIV Infection

Answer 11

asymptomatic infection

Question 12

Stage 2 of HIV Infection

Answer 12

early, general symptoms of disease

Question 13

Stage 3 of HIV Infection

Answer 13

moderate symptoms

Question 14

Stage 4 of HIV Infection

Answer 14

severe symptoms, often leading to death

Question 15

Adverse effects of antiretroviral drugs

Answer 15

Headache, nausea, vomiting, rash, chills, fever, diarrhea

Question 16

which drug can be given to HIV positive pregnant women?

Answer 16

retrovir

Question 17

most common antiretroviral drug combination

Answer 17

dolutegravir and Truvada (Truvada is emtricitabine and tenofovir

Question 18

Hepatitis B

Answer 18

Serious potential fatal viral infection of the liver.

Question 19

how is Hepatitis B spread

Answer 19

Spread by blood, sexual contact or needles/instruments

Question 20

what suffixes are used for antiviral drugs

Answer 20

• vir

- dine

Question 21

elements of the immune system

Answer 21

Certain types of WBC
Proteins in blood
Interferon
Lymphocytes (B & T)

Question 22

what do B lymphocytes do?

Answer 22

Become cells that produce antibodies

Question 23

what do T lymphocytes do?

Answer 23

Attack antigens directly and help control the immune response

Question 24

why are immunosuppressants used?

Answer 24

To suppress immune response to prevent organ rejection after transplants (Lifelong)
To treat autoimmune diseases

Question 25

Drug of choice for organ rejection (kidney, liver, and heart)

Answer 25

cyclosporine

Question 26

how to cytotoxic drugs supress the immune system?

Answer 26

by killed B and T's

Question 27

uses of antihistamines

Answer 27

Allergies - mild Motion sickness Insomnia Common cold may decrease rinorrhea through anticholinergic action

Question 28

difference between nsaids and aceteminophen?

Answer 28

acetaminophen is not an antinflamatory

Question 29

what are the uses of NSAIDS

Answer 29

Suppress inflammation Relieve pain Reduce fever

Question 30

Adverse effects of NSAIDS

Answer 30

GI issues | Renal effects

Question 31

who can not have asprin

Answer 31

children | pregnant women

Question 32

Antidote for acetaminophen overdose

Answer 32

aceylcysteine

Question 33

adverse effects of gold salts

Answer 33

stomatitis, gingivitis, colitis, bone marrow depression

Question 34

what does Allopurinol treat?

Answer 34

chronic gout

Question 35

3 drugs used for Fibromyalgia

Answer 35

1. pregabalin 2. duloxetine 3. milnacipran

Question 36

what is Chloroquine used from

Answer 36

prevention of malaria

Question 37

adverse effects of antimalarial

Answer 37

``` Headache Dizziness Fever Chills Malaise Nausea Vomiting Hepatic Dysfunction ```

Question 38

malarone

Answer 38

combination of 2 drugs prevent malaria

Question 39

National Childhood Vaccine Act 1986 requires what?

Answer 39

permanent record: Date of vaccination Route and site Vaccine type, mfg, lot number and expiration date name and title of person administering vaccine

Question 40

how is Hep A spread

Answer 40

from fecal - oral

Question 41

what allergy would you not give the flu shot to ?

Answer 41

egg allergy

Question 42

tumor staging and grading

Answer 42

TNM T: extent of primary tumor N: lymph node involvement M: extent of metastasis

Question 43

what drugs are used for breast cancer

Answer 43

hormonal anticancer drugs

Question 44

which generation of antihistamines are sedating?

Answer 44

first generation

Question 45

only non sedating second generation antihistamine

Answer 45

loratadine

Question 46

The prototype drug for the NSAIDs

Answer 46

aspirin

Question 47

Adverse effects of acetaminophen

Answer 47

hepatotoxicity | hepatic necrosis