Week 5

Question 1

think about hormones

how exercise helps with artery health

Answer 1

exercise -> increase hormone nitric oxide production (shear stress of arterial pathway) -> artery dilation -> decreased BP -> decrease AS risk

Question 2

nitric oxide

Answer 2

• produced by endothelial cells

Question 3

anti-atherogenic effects of endothelium and NO

Answer 3

• prevent AS symptoms
• prevents monocytes and macrophages in subintimal space
• prevents LDL etnering
• VD decreasing shear and pressure
• decreased smooth muscle proliferation
• decreased superoxide anions, ox-LDL and foam cell formation

Question 4

how endurance stimualtes eccentric hypetrophy of heart

Answer 4

increased volume of ventricle -> increased stroke volume -> eccentric hypertrophy (walls thickening and diameter increase) -> increased VO2 peak

Question 5

think about fats/blood

impact of regular exercise (bouchard study)

Answer 5

• plasma HDL-C decrease
• plasma triclygeride decrease
• resting systolic BP decrease
• plasma fasting insulin increase

Question 6

20 20 10 10 (S)

High normal BP

Answer 6

120-139 / 80-89

Question 7

20 20 10 10 (S)

Grade 1 Hypertension

Answer 7

140-159 / 90-99

Question 8

20 20 10 10 (S)

Grade 2 Hypertension

Answer 8

160-170 / 100-109

Question 9

20 20 10 10 (S)

Gade 3 Hypertension

Answer 9

180+ / 110+

Question 10

BP changes for decreased CV risk?

Answer 10

• SBP 8-10 decreased
• DBP - 4-6 decreased

Question 11

Statin

Answer 11

medication that can lower cholesterol (25% decreased LDL-C)

Question 12

Primum Non Nocere

Answer 12

goal of exercise as therapy to achieve physiological, symptomatic, psychological and vocational benefits for patients at low risk

Question 13

Exercise Paradox

Answer 13

chronic exercise risk (30-40%) for naive older individuals (minimize risk and monitor)