Week 5 - Neurons Flashcards

1
Q

What is an action potential?

A

A transient all-or-nothing electrical current that is conducted down the axon when the membrane potential reaches the threshold of excitation.

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2
Q

What is an axon?

A

Part of the neuron that extends off the soma, splitting several times to connect with other neurons; main output of the neuron.

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3
Q

What is the cell membrane?

A

A bi-lipid layer of molecules that separates the cell from the surrounding extracellular fluid.

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4
Q

What is a dendrite?

A

Part of a neuron that extends away from the cell body and is the main input to the neuron.

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5
Q

What is diffusion?

A

The force on molecules to move from areas of high concentration to areas of low concentration.

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6
Q

What is electrostatic pressure?

A

The force on two ions with similar charge to repel each other; the force of two ions with opposite charge to attract one another.

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7
Q

What are excitatory postsynaptic potentials?

A

A depolarizing postsynaptic current that causes the membrane potential to become more positive and move towards the threshold of excitation.

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8
Q

What are inhibitory postsynaptic potentials?

A

A hyperpolarizing postsynaptic current that causes the membrane potential to become more negative and move away from the threshold of excitation.

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9
Q

What are ion channels?

A

Proteins that span the cell membrane, forming channels that specific ions can flow through between the intracellular and extracellular space.

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10
Q

What is an ionotropic receptor?

A

Ion channel that opens to allow ions to permeate the cell membrane under specific conditions, such as the presence of a neurotransmitter or a specific membrane potential.

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11
Q

What isa myelin sheath?

A

Substance around the axon of a neuron that serves as insulation to allow the action potential to conduct rapidly toward the terminal buttons.

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12
Q

What are neurotransmitters?

A

Chemical substances released by the presynaptic terminal button that acts on the postsynaptic cell.

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13
Q

What is the nucleus?

A

Collection of nerve cells found in the brain which typically serve a specific function.

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14
Q

What is the resting membrane potential?

A

The voltage inside the cell relative to the voltage outside the cell while the cell is a rest (~ -70mV).

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15
Q

What is the sodium-potassium pump?

A

An ion channel that uses the neuron’s energy (adenosine triphosphate, ATP) to pump three Na+ ions outside the cell in exchange for bringing two K+ ions inside the cell.

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16
Q

What is a soma?

A

Cell body of a neuron that contains the neucleus and genetic information, and directs protein synthesis.

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17
Q

What are spines?

A

Protrusions on the dendrite of a neuron that form synapses with terminal buttons of the presynaptic axon.

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18
Q

What are synapses?

A

Junctions between the presynaptic terminal buttion of one neuron and the dendrite, axon, or soma of another postsynaptic neuron.

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19
Q

What is a synaptic gap?

A

Also known as the synaptic cleft; the small space between the presynaptic terminal button and the postsynaptic dendritic spine, axon, or soma.

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20
Q

What are synaptic vesicles?

A

Groups of neurotransmitters packaged together and located within the terminal button.

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21
Q

What is the terminal button?

A

The part of the end of the axon that form synapses with postsynaptic dendrite, axon, or soma.

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22
Q

What is the threshold of excitation?

A

Specific membrane potential that the neuron must reach to initiate an action potential.

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23
Q

What are the three main categories of neurons in the brain?

A
  1. Unipolar neurons
  2. Bipolar neurons
  3. Multipolar neurons
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24
Q

What are motor neurons?

A

Neurons that allow us to initiate movement and behaviour (allows us to interact with the world).

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25
Q

What are interneurons?

A

Neurons that that process the sensory input from our environment into meaningful representations, plan the appropriate behavioral response, and connect to the motor neurons to execute these behavioral plans.

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26
Q

What are sensory neurons?

A

Neurons that help us receive information about the world around us.

27
Q

What are unipolar neurons?

A

Neurons that are structured in such a way that is ideal for relaying information forward, so they have one neurite (axon) and no dendrites. They are involved in transmission of physiological information from the body’s periphery such as communicating body temperature through spinal cord up to the brain.

28
Q

What are bipolar neurons?

A

Neurons that are involved in sensory perception such as perception of light in the retina of the eye. They have one axon and one dendrite which help acquire and pass sensory information to various centres in the brain.

29
Q

What are multipolar neurons?

A

Neurons that are the most common and they communicate sensory and motor information in the brain. They have one axon and many dendrites which allows them to communicate with other neurons.

30
Q

What are glia cells?

A

Cells in the brain that have several functions. They participate in neuronal support, but do NOT participate in the communication between cells in the same fashion as neurons do.

31
Q

What are oligodendroglias?

A

Glia cells that form myelin sheaths.

32
Q

What are microglias and astrocytes?

A

Glia cells that that digest debris of dead neurons, carry nutritional support from blood vessels to the neurons, and help to regulate the ionic composition of the extracellular fluid.

33
Q

What are 5α-reductases?

A

Enzymes that require to convert testosterone to 5α-dihydrotestosterone.

34
Q

What is aggression?

A

A form of social interaction that include threat, attack, and fighting.

35
Q

What are aromatases?

A

Enzymes that convert androgens into estrogens.

36
Q

What is chromosonal sex?

A

The sex of an individual as determined by the sex chromosones (typically XX or XY) received at the time of fertilization.

37
Q

What is defeminization?

A

The removal of the potential for female traits.

38
Q

What is demasculinization?

A

The removal of the potential for male traits.

39
Q

What are dihydrotestosterones (DHT)?

A

Primary androgens that are androgenic steroid products of testosterone and bind strongly to androgen recptors.

40
Q

What is a endocrine gland?

A

A ductless gland from which hormones are released into the blood system in response to specific biological signals.

41
Q

What is estrogen?

A

Any of the C18 class of steroid hormones, so named because of the estrus-generating properties in females. Biologically important estrogens include estradiol and estriol.

42
Q

What is gonadal sex?

A

The sex of an individual as determined by the possession of either ovaries or testes. Females have ovaries, whereas males have testes.

43
Q

What are hormones?

A

Organic chemical messengers released from endocrine cells that travel through the blood to interaxt with target cells at some distance to cause a biological response.

44
Q

What is maternal behaviour?

A

Parental behaviour performed by the mother or other female.

45
Q

What are neurontransmitters?

A

Chemical messengers that travel between neurons to provide communication. Some like norepinephrine can leak through into the blood stream and act as hormones.

46
Q

What is oxytocin?

A

A peptide hormone secreted by the pituitary gland to trigger lactation, as well as social bonding.

47
Q

What is parental behavior?

A

Behaviors performed in relation to one’s offspring that contributes directly to the survival of those offspring.

48
Q

What is paternal behavior?

A

Parental behavior performed by the father or other male.

49
Q

What is progesterone?

A

A primary progestin that is involved in pregnancy and mating behaviors.

50
Q

What is progestin?

A

A class of C21 steroid hormones named for their progestational (pregnancy-supporting) effects.

51
Q

What us a prohormone?

A

A molecule that can act as a hormone itself or be converted into another hormone with different properties. Example testosterone can be a hormone, or a prohormone.

52
Q

What is prolactin?

A

A protein hormone that is highly conserved throughout the animal kingdom. It has many biological functions associated with reproduction and synergistic actions with steroid hormones.

53
Q

What is a recptor?

A

A chemical structure on the cell surface or inside of a cell that has an affinity for a specific chemical configuration of a hormone, neurotransmitter, or other compound.

54
Q

What is a target cell?

A

A cell that has receptors for a specific chemical messenger (hormone or neurotransmitter)

55
Q

What is testosterone?

A

The primary androgen secreted by the testes of most vertebrate animals, including men.

56
Q

What is agonists?

A

A drug that increases or enhances a neurotransmitter’s effect.

57
Q

What is antagonist?

A

A drug that blocks a neurotransmitter’s effect.

58
Q

What is an enzyme?

A

A protein produced by a living organism that allows or helps a chemical reaction to occur.

59
Q

What is enzyme induction?

A

Process through which a drug can enhance the production of an enzyme.

60
Q

What is pharmacokinetics?

A

The action of a drug through the body, including absorption, distribution, metabolism, and excretion.

61
Q

What is polypharmacy?

A

The use of many medications.

62
Q

What are psychoactive drugs?

A

A drug that changes mood or the way someone feels.

63
Q

What is psychotropic drug?

A

A drug that changes mood or emotion, usually used when talking about drugs prescribed for various mental conditions.