Week 5 (parts 1, 2 and 3) Flashcards
(37 cards)
Part 1
stroke
what is the brainstem
Oldest part of the brain.
Links the Cerebrum and the spinal cord.
Comprises of the medulla, midbrain, and the pons.
Connects to the Cerebellum.
what is the cerebellum
Attached to the brain stem via 3 peduncles
Cortex is wrinkled and divided into lobes
Has both grey and white matter
Involved in maintaining balance and control
what is the cerebrum
Cortex of grey matter
Deeper groups of white matter
Include the Basal ganglia
4 lobes, frontal, parietal, occipital, temporal
Wrinkled with hillocks (gyri) and grooves (sulci)
what is the motor homunculus
This maps to the primary motor cortex in the frontal lobe
what is the sensory homunculus
This maps to the primary somatosensory cortex in the parietal lobe
how is circulation controlled by the brain
The brain is supplied with blood both anteriorly via the internal carotid arteries and posteriorly via the vertebral arteries
To limit the possibility of loss of blood supply the brain has evolved a circular vascular anatomy which is called the Circle of Willis
what is the role of the circle of willis
Maintaining a blood supply to the brain and maintaining homeostasis are vital to maintaining life
what are the 2 types of stroke
Infarcts:
* Due to blockage in the brain (85% of strokes)
* Embolic
* Thrombotic
* Due to blockage in the arterial supply to the brain usually (sometimes venous supply but rare)
Intracerebral Haemorrhage (ICH):
* Due to bleeding in or around the brain (haemorrhagic strokes)
* Bleeding into the brain tissue itself – different to bleeding into and around the meninges
what are the causes of stroke
A stroke can happen to anyone at any time – including children
Age
High Blood pressure (big risk for haemorrhages/bleeds)
Diabetes
Atrial Fibrillation
High Cholesterol
Family History
Ethnicity
Sickle Cell Disease
what are the classifications of stroke
TACS – Total Anterior Circulation Stroke
PACS – Partial Anterior Circulation Stroke
LACS – Lacunar Stroke
POCS – Posterior Circulation Stroke
what are the basic signs and symptoms of stroke
- Sudden onset weakness
- Sudden onset sensory loss
- Difficulty word finding or speaking
- Sudden blurred vision
- Sudden loss of sight
- Sudden memory loss
- Confusion
what the main treatments for stroke
Ischaemic
Thrombolysis
Thrombectomy
Antiplatelet v anticoagulant
Cholesterol control
BP control
Smoking cessation
Exercise
Nutrition
Rehabilitation
Haemorrhagic
Cholesterol control
BP control
Smoking cessation
Exercise
Nutrition
Rehabilitation
Part 2
supporting structures of the CNS
what are the supporting structures of the CNS
The brain is an important structure so is protected from contusion and infection by:
Glial Cells
The meninges
The cerebrospinal fluid (CSF)
The skull
what are Glial cells
These are dispersed between the nerve cells and hold the neurons of the CNS in place. There are four main types:
Oligodendrocytes – where did we discuss these before?
Microglia
Ependymal cells
Astrocytes
what are Meninges
These are three layers of fibrous material that surround the brain and spinal cord to prevent it from injury and infection
The meninges work together with the CSF to cushion the brain and prevent it moving too much with in the skull
what is Pia Mater
Very thin and lies directly on the surface of the brain
Gives the brain its shiny look
what is Arachnoid Mater
Lies between the Dura and Pia Mater
There is a space between the Arachnoid and Pia Mater called the Arachnoid space – this contains CSF (see below) and arterial blood supply to the outside of the brain
The arachnoid layer is attached to the pia mater via fibrous strands - making it look like a spider – hence its name
what is Dura Mater
This is the tough outer layer of the meninges
It is directly attached to the skull
Except where it allows space for the venous supply
what is Cerebro Spinal Fluid
Straw coloured viscous fluid produced in the lateral ventricles
Circulates around the brain and spinal cord in the subarachnoid space
Approx 500ml produced per day. 125-150ml circulating at any time.
how is the brain provided for via circulation
The brain is supplied with blood both anteriorly via the internal carotid arteries and posteriorly via the vertebral arteries
To limit the possibility of loss of blood supply the brain has evolved a circular vascular anatomy which is called the Circle of Willis
what is the function of the circle of Willis
Maintaining a blood supply to the brain and maintaining homeostasis are vital to maintaining life
what brain lobes do the arteries supply
Can you guess/tell me which lobes or areas of the brain the following arteries supply AND what your signs and symptoms would be if you had loss of blood supply to that area??
Middle cerebral artery (MCA)?
Posterior cerebral artery (PCA)?
Anterior cerebral artery (ACA)?
Posterior inferior cerebellar artery?