week 6 proteins Flashcards
(73 cards)
what are proteins?
proteins are amino acids linked together end-to-end via peptide bonds
what is a peptide bond?
chemical bond formed between amine group end of one amino acid and the acid group of the next
what is a condensation reaction
joins amino acids together via removal of water
what is hydrolysis?
separation of amino acids via addition of water
when two amino acids are together what are they called? three? 10 or more?
two: dipeptide
three: tripeptide
10 or more: polypetide
what are the 4 kinds of protein structure?
primary
secondary
tertiary
quaternary
what is the primary structure?
amino acid sequence
what is the secondary sequence?
weak electrical attractions (e.g hydrogen bond between H and O)
what is the tertiary structure?
folding of the long AA chain - hydrophobic amino acids cluster on the inside while hydrophilic face the outside of the structure
what is the shape of the protein critical for?
their function
what is globular hemoglobin?
4 polypeptides combined at the quaternary-level and each carry O2 and Fe (iron)
what is denaturation?
- when subjected to heat, acid, or other conditions that disturb stability, proteins uncoil and lose their function
- does not change their “primary” shape or amino acid sequence, but will cause them to lsoe their shape, thus their function
what does an amino acid contain?
contain an amine group (N-containing), acid group (COOH), and side chain/group
what does the side chain do?
creates a unique chemical structure, differentiates one AA from another; makes AA differ in size/shape/electrical change
what are Essential Amino Acids
cannot be synthesized at all. must be supplied by diet
What are proteins made of?
Amino acids linked together via peptide bonds.
What is the process called that joins amino acids together?
Condensation.
What is the process that separates amino acids?
Hydrolysis.
What do you call two amino acids linked together?
Dipeptide.
What do you call three amino acids linked together?
Tripeptide.
What is the term for a chain of 10 or more amino acids?
Polypeptide.
What is the primary structure of a protein?
AA sequence.
What type of bonds are formed in the secondary structure of proteins?
Weak electrical attractions, such as hydrogen bonds.
In the tertiary structure of proteins, where do hydrophobic amino acids cluster?
On the inside of the structure.