Week 7 Flashcards
(16 cards)
What percentage of circulating WBCs do neutrophils make up?
50-70
What growth factors are essential for neutrophil production?
G-CSF, GM-CSF, and IL-3
Döhle body in neutrophils?
blue cytoplasmic inclusion indicating infection or stress response.
What do eosinophils target?
Parasitic infections and allergic reactions.
What proteins do eosinophils release to kill parasites?
Major Basic Protein (MBP), eosinophil cationic protein, and eosinophil peroxidase
What do basophils release during allergic reactions?
Histamine, serotonin, and heparin.
What percentage of WBCs do monocytes make up?
2-10% of total WBCs.
What are the two major functions of macrophages?
Phagocytosis and antigen presentation to T cells.
What is the primary antigen-presenting cell (APC) in the immune system?
Dendritic cells (derived from monocytes).
What causes lymphocytosis?
Viral infections (e.g., Epstein-Barr Virus (EBV), mononucleosis, toxoplasmosis).
What parasitic infection is associated with lymphocytosis and transmitted by cats?
Toxoplasmosis (caused by Toxoplasma gondii).
What does HLA stand for?
Human Leukocyte Antigen.
What test determines if a recipient has antibodies against a donor’s tissue?
Lymphocyte cross-matching.
What laboratory technique is commonly used to analyze WBC subtypes?
Flow cytometry.
What staining technique is used for blood smears to examine WBC morphology?
Wright-Giemsa stain.
What molecular test is used to detect viral infections like HIV?
PCR test
