Week 8 Medications for Endocrine Flashcards

(67 cards)

1
Q

Pituitary drug example

A

Desmopressin

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2
Q

What is the purpose of desmopressin and how does it work?

A

Desmopressin manages nocturnal enuresis and it manages diabetes insipidus (large urinary output) by decreasing urinary output and thirst

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3
Q

Adrenal Meds examples

A

*Glucocorticoids
*Betamethasone
*Budesonide
*Hydrocortisone
*Triamcinolone
*Methlyprednisone
*Prednisone

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4
Q

what are adrenal meds typically used for?

A

short term tx of inflammatory diseases

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5
Q

Topical adrenal med examples and indication

A

Topical (Rash- dermatitis -
Triamcinolone, hydrocortisone),
-for little areas
-CAN OD

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6
Q

inhaled/nasal adrenal meds indication and examples

A

Inhaled/nasal (allergies & Asthma & COPD -
Rhinocort, Pulmicort, Flovent),
-respiratory

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7
Q

injection adrenal meds indication and example

A

Injection (PN, asthma, COPD-
Methylprednisolone)

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8
Q

oral/systemic adrenal med examples

A

Oral/systemic (Arthritis, systemic lupus, allergic reactions-prednisone)- long term

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9
Q

what are all the SE and AE of adrenal meds

A

Delayed wound healing (especially in long term use)
Immunosuppression (immunosuppressant effect)
Risk of peptic ulcers
Rebound affect
Increases blood glucose (not inherently a contraindication of diabetes)
Weight gain (messes with adrenal gland and fluid retention like in cushin’s, the overproduction of the steroid is causing weight gain)
Growth issues in kids, stunted
Insomnia (give AM) will impact the circadian rhythm
Neves, shakiness (restless)
Osteoporosis
Causes thinning of the skin with topical shorter term

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10
Q

reprised what are the SE AE of adrenal meds?

A

It causes restlessness (shakes, nerves, insomnia)
Causes growth issues including weight because they are steroids
Cushins and water retnetion
Skin irritation with topical uses
Weakens the immune system: nonhealing wounds, peptic ulcers, immunosuppression, infection
Osteoporosis

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11
Q

What is a severe complication of adrenal meds

A

Adrenal crisis if stopped suddenly due to sudden drop in serum cortisone levels
the adrenal glands of the kidneys will stop production of cortisone levels due to the decreased production

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12
Q

what are the symptoms of adrenal meds?

A

hyponatremia, hypotension,
loss of consciousness, death

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13
Q

what is a caution of adrenal meds?

A

diabetes because it can increase sugar levels

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14
Q

what is hypothyroid treated with

A

levothyroxine
by replacing hormones the thyroid cant produce.

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15
Q

what are the nursing implications of thyroxine?

A

Take it with water in the mornings on an empty stomach
(about 1 hr before eating)
Make sure not to take it with other meds to avoid interactions
Monitor for adverse effects like tachy, HTN, anxiety (HYPER)
DONT switch brands
safe for pregnancy
it can take 5-8 weeks to regulate

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16
Q

Adrenal meds med administration

A

make sure to taper prednisone to avoid adrenal crisis
give with food to avoid GI upset
give in the AM
avoid grapefruit juice (increases effect)
infection prevention (immunosupression)

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17
Q

Adrenal meds implications

A

assess renal disease (affects kidneys)
weight/height (cushins, and stunted growth)
glucose (increases blood sugar)
electrolytes (symptoms of adrenal crisis)

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18
Q

Antithyroid agents

A

Radioactive iodine 131
-1 dose?

Propylthiouracil PTU
long term

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19
Q

Indication radioactive iodine

A

Hyperthyroidism
Acute thyrotoxicosis
Graves disease

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20
Q

what is the nursing implication of radioactive iodine

A

used for candidates who are not eligible candidates

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21
Q

radioactive iodine SE AE

A

metallic taste
swollen gums and sore teeth

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22
Q

what is the indication for propylthiouracil PTU

A

hyperthyroidism
Graves
Emergency treatment
Thyrotoxicosis

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23
Q

SEAE of propyliouracil

A

long term use can become too much causes hypothyroidism
hepatitis

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24
Q

Nursing implication of propylthiouracil

A

will not cure bulging eyes

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25
parathyroid meds
bisposphonates calcitonins
26
bisphosphonates indication
slow normal and abnormal bone resorption
27
bisphosphonates SE AE
osteonecrosis of the jaw ocular inflammation esophagitis bone pain
28
bisphosphonate nsg implication
ability to sit up 30 mins!
29
Calcitonin's indication and SE AE
stops bone reabsorption (decrease ca levels)
30
calcitonin SE AE
flushed face and hands nasal spray will cause irritation and bleeding
31
Rapid acting insulin example
Lispro (humolog) Aspart (novolog)
32
Onset and peak of rapid acting insulin Lispro and Aspart
onset 5-15min peak 1-2 hrs
33
Short Acting Insulin example
Regular (humulin)
34
onset and peak of regular (Humulin)
takes longer than rapid 30-60min 2.5h peak
35
route of regular insulin
SQ IV REGULAR is the ONLY insulin that is IV!!!
36
intermediate-acting example onset peak
NPH 1-2 hour onset 4-8 hr peak
37
Long acting insulin examples
glargine (Lantus) detemir (Levemir)
38
glargine detemir onset peak
1-2 hrs no peak duration: 24 hrs
39
Combination insulins:
Humulin 70/30 or Novolin 70/30 NPH and Rapid
40
indication of antidiabetic treatments
diabetes severe hyperkalemia
41
SE AE of antidiabetic medication INUSULINs
hypoglycemia lipohypertrophy
42
Nursing implications of insulin
check the blood glucose levels evaluate A/C
43
what should nurses know about insulins
ensure food is available for rapid and short acting insulins long acting insulin dosing is daily or every 12 hours Long acting CANNOT be mixed with other types of insulin
44
med admin insulin
rotating sites adjusting dose for pt with infections spike w food clear then cloudy pumps are rapid or short acting only (for control)
45
storage of insulin
unopened can be in the fridge til expiration room temp insulins can be used for 1month max
46
oral antidiabetic treatments ex
metformin
47
metformin indication
Diabetes type II polycystic ovarian syndrome metabolic syndrome (due to insulin resistance)
48
SEAE of metformin
Nausea and Diarrhea
49
Interactions with metformin
alcohol
50
why does ETOH intereact w/ metformin?
it inhibits breakdown of lactic acid which can intensify lactic acidosis to counteract lactic acidosis the body will begin to breath out rapidly iodine containing contrasts for CT
51
nursing implications for metformin
tapper up the dose to decrease GI issues take it with food hold the med for 48 hours if they will have a CT scan and avoid 48 hours after hard on the kidneys -may need to elimiate other nephrotoxic drugs
52
what should a nurse monitor for a patient on metformin
CREATINE
53
Sulfonylureas examples
Glimepiride Glipizide Glyburide
54
Sulfonylureas indication
for type II diabetes -oral will never be used for type I
55
SE AE of sulfonylureas
hypoglycemia weight gain heartburn
56
Interactions
beta blockers, alcohol
57
nursing implications of sulfonyulureas
take in the morning 30 mins before breakfast
58
piolitazone indication Thizolidnediones
Diabetes melluitis type II
59
pigolitazone SE AE
moderate weight gain edema mild anemia hepatic toxicity
60
nsg implication of pioglitazone
2011 actos causes bladder cancer lawsuit still used in US not in other coutnries
61
Dipeptidyle peptidoase IV inhibitors
Sitagliptin
62
sitagliptin is used to treat
type II diabetes either on its own or with metformin sulfonylurea but not with INSULIN
63
SE AE of sitagliptin SE AE
upper respiratory tract infections headache diarrhea
64
nsg implication of sitagliptin
hypoglycemia cann occur especiialy if it is used with sulfonylurea
65
Glucose elevating med examples
Glucagon 50% dextrose in water concentrated glucose PO -chewable tablets, gels
66
nsg implication of
assess blood glucose before administering glucagon ' higher levels of glucoagon are typically not harmful asses pt ability to swallow
67
pt education of blood raising meds
keep glucose with you at all times