WS 1

Question 1

define therapeutic index

Answer 1

expresses the relationship between a drug’s therapeutic and harmful effects.

Question 2

how is the therapeutic index calculated

Answer 2

LD50/ED50

Question 3

define half life when it comes to drugs

Answer 3

The time it takes for the drug to fall by half of its blood concentrations

Question 4

what are the four components of a drug regimen

Answer 4

dosage
route
frequency
duration

Question 5

Define pharmacokinetics. (two points)

Answer 5

The complex sequence of events that occurs after a drug is administered to a patient.

The branch of pharmacology concerned with the movement of drugs within the body.

Question 6

What kind of names are the drug names Clavamox and Simplicef?

Answer 6

They are both trade names, also known as proprietary or brand names.

Question 7

Generic name of Clavamox

Answer 7

amoxicillin with clavulanic acid

Question 8

Generic name of Simplicef

Answer 8

cefpodoxime proxetil

Question 9

What kind of names are the drug names meloxicam and carprofen?

Answer 9

generic names

Question 10

Trade name of meloxicam

Answer 10

Metacam

Question 11

Trade name of carprofen

Answer 11

Rimadyl

Question 12

what kind of name is:

Carprofen: (±)-6-chloro-α-methylcarbazole-2-acetic acid

Or (6-Chloro-9H-carbazol-2-yl)propanoic acid

Answer 12

chemical name

Question 13

represents the degree to which a drug produces its desired response in a patient.

Answer 13

efficacy of a drug

Question 14

9 factors that may influence the absorption of a drug

Answer 14

• Method of administration
• pH of the drug and its ionization status
• Charge of the drug
• the absorptive surface area
• the blood supply to the area
• the solubility of the drug
• the dosage form
• the status of the GI tract
• interactions with other drugs