XIII - The Lung Flashcards Preview

Pathology > XIII - The Lung > Flashcards

Flashcards in XIII - The Lung Deck (126)
Loading flashcards...
61

Form of lung cancer that is thought to arise from neuroendocrine cells, called Kulchitsky cells, that line the bronchial mucosa and resemble intestinal carcinoids. Nests of small, rounded, uniform cells with "salt and pepper" chromatin.

Bronchial carcinoids(TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 534

62

Presence of fluid in the pleural space.

Pleural effusion(TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 535

63

Air or other gas in the pleural sac.

Pneumothorax(TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 535

64

A collection of whole blood in the pleural cavity.

Hemothorax(TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 535

65

A pleural collection of a milky lymphatic fluid containing microglobules of lipid.

Chylothorax(TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 535

66

A rare cancer seen in patients who work in shipyards, miners and insulators. Lesion is preceeded by extensive pleural fibrosis and plaque formation. May be epithelial, sarcomatoid or biphasic in morphology.

Malignant mesothelioma(TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 536

67

Rare neoplasm with strong links to EBV and high frequency among the Chinese population. Characterized by large epithelial cells having indistinct borders (syncitial growth) and prominent eosinophilic nucleoli.

Nasopharyngeal carcinoma(TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 537

68

Smoothe, hemispherical protrusions located on the true vocal cords, composed of fibrous tissue and covered by stratified squamous mucosa.

Vocal cord nodules(TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 537

69

A benign neoplasm usually on the true vocal cords that forms a soft, raspberry-like excresence rarely more then 1 cm in diameter. Consists of multiple, slender, finger-like projections.

Laryngeal papilloma(TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 537

70

Histologic manifestation of acute respiratory distress syndrome and acute lung injury.

Diffuse alveolar damage(TOPNOTCH)Robbins Pathologic Basis of Disease, 9th Ed. p. 672

71

A 70 y/o male presented to the ER with a 10 day history of fever followed by rapidly progressive dyspnea for 3 days prior to admission. Physical examination revealed tachypnea, central cyanosis, and extensive fine inspiratory crackles of the chest. Severe hypoxemia was noted on ABG. Chest radiograph revealed bilateral diffuse alveolar infiltrates with normal cardiac size. An extensive ground glassing was also. Diagnosis? Characteristic histologic picture expected for this condition?

ARDS. Hyaline membranes lining the alveolar walls. (TOPNOTCH)

72

The key initiating events and the basis of lung damage in ARDS

Damage to endothelial and alveolar epithelial cells. (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 674

73

Disease characterized by abnormally large alveoli separated by thin septa with only focal centriacinar fibrosis.

Emphysema (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 677

74

Mild chronic inflammation of the airways (predominantly lymphocytes) and enlargement of mucus-secreting glands of the trachea and bronchi are seen in:

Chronic bronchitis(TOPNOTCH)Robbins Basic Pathology, 9th Ed. p. 679

75

A 55 y/o female presented with chronic cough, productive of thick, tenacious sputum, recurrent episodes of fever associated with pleuritic chest pain. Crackles were noted on auscultation. Chest radiograph showed presence of "tram tracks". The most likely diagnosis:

Bronchiectasis(TOPNOTCH)

76

Dilation of bronchi and bronchioles, with acute and chronic inflammatory exudation, desquamation of the lining epithelium and extensive areas of ulceration, are characteristics of what disease?

Bronchiectasis (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 683

77

Earliest feature of chronic bronchitis

Hypersecretion of mucus in the large airways. (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 678

78

Subbasement membrane fibrosis, hyperplasia of bronchial wall muscle, hypertrophy of bronchial glands, and inflammatory infiltrate in the bronchial wall. These are morphologic findings in:

Asthma(TOPNOTCH) Robbins Pathologic Basis of Disease, 9th ed., p. 682

79

Fundamental abnormality in atopic asthma

Exagerrated TH2 response (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 680

80

Key inflammatory cells found in asthma

Eosinophils (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 683

81

Most common bacterial cause of acute exacerbation of COPD

Haemophilus influenzae. (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 703

82

A 3 y/o child was brought to ER due to sudden onset of high fever, labored breathing, and drooling. The most likely cause of this condition is:

Haemophilus influenzae (TOPNOTCH)

83

3 most common causes of otitis media in children

Streptococcus penumoniae, Haemophilus influenzae, Moraxella catarrhalis (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 703

84

Most freqent cause of gram negative bacterial pneumonia.

Klebsiella pneumoniae (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 703

85

A 45 y/o alcoholic male presented with fever, tachypnea, and cough with thick, mucoid, blood-tinged sputum. Chest radiograph showed right middle lobe opacification and bulging fissure sign. The most likely cause of pneumonia in this case is:

Klebsiella pneumoniae (TOPNOTCH)

86

An important cause of secondary bacterial pneumonia in children and adults following a viral respiratory illness (measles, influenza)

Staphylococcus aureus (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 703

87

Cause of pneumonia associated with high incidence of lung abscess and empyema

Staphylococcus aureus (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 703

88

Most common cause of community acquired pneumonia

Streptococcus pneumoniae. (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 707

89

Distribution of pneumonia caused by Streptococcus pneumoniae, lobar or patchy consolidation?

Lobar (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 707

90

Predominant histologic pattern in viral pneumonia

Interstitial inflammatory reaction of the walls of alveoli (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 707