XIII - The Lung Flashcards Preview

Pathology > XIII - The Lung > Flashcards

Flashcards in XIII - The Lung Deck (126)
Loading flashcards...
91

Cause of pneumonia seen particularly in organ transplant recipients.

Pneumonia caused by Legionella pneumophila. (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 708

92

Common cause of pneumonia in persons with cystic fibrosis, burn victims and in patients with neutropenia

Pneumonia caused by Pseudomonas aeruginosa (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 708

93

Most frequent cause/mechanism of lung abscess

Aspiration of infective material (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 708

94

Cardinal histologic change in lung abscess

Suppurative destruction of lung parenchyma within the central area of cavitation (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 709

95

Major morphologic correlate of chronic rejection

Bronchiolitis obliterans (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 712

96

Type of emphysema in smoking

Centriacinar (centrilobular) Emphysema(TOPNOTCH)

97

Most common histologic pattern of bronchogenic carcinoma

Adenocarcinoma (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 715

98

Most common site of lung squamous cell carcinoma

Central/hilar region (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 715

99

Most common type of lung cancer in men

Squamous cell carcinoma (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 716

100

Histologic characteristics of this type of lung carcinoma is keratinization and/or intercellular bridges.

Squamous cell carcinoma (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 716

101

Pulmonary embolism could lead to this type of shock

Cardiogenic shock (TOPNOTCH)

102

Mechanism of pulmonary edema in left sided CHF.

Increased hydrostatic pressure(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 671

103

Associated with medial hypertrophy of the pulmonary muscular and elastic arteries, pulmonary arterial atherosclerosis, and right ventricular hypertrophy.

Pulmonary hypertension(TOPNOTCH)Robbins Basic Pathology, 9th Ed. p. 700

104

An autoimmune disease characterized by rapidly progressive glomerulonephritis and necrotizing hemorrhagic interstitial pneumonitis.

Goodpasture syndrome(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 701

105

Presents with cough, fever, and copious foul-smelling sputum, usually with antecedent primary lung infection. Cardinal histologic change in this condition is suppurative destruction of lung parenchyma within the central area of cavitaion.

Lung abscess(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 709

106

Pneumonia acquired by inhalation of dust particles from soil contaminated with bird or bat droopings that contain micronidia. Symptoms resemble those of tuberculosis.

Histoplasmosis(TOPNOTCH)Robbins Basic Pathology, 9h Ed. p. 709

107

The most common site of metastatic neoplasm

Lung(TOPNOTCH)Robbins Basic Pathology, 9h Ed. p. 721

108

Sudden death in pulmonary embolism is caused by:

Blockage of blood flow through the lungs.(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 698

109

Inflammatory cell implicated in the pathogenesis of ARDS (A) type II pneumocyte (B) neutrophil (C) fibroblast (D) eosinophil

neutrophil (TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 482

110

Of the types of emphysema that cause clinically significant airway obstruction, which one is the commonest? (A) centriacinar (B) panacinar (C) distal acinar (D) irregular

Centriacinar (centrilobular) Emphysema(TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 485

111

In chronic bronchitis, a Reid index of more than 0.4 is diagnostic. The Reid index is the ratio of the thickness of the (A) metaplastic mucosa to the submucosal gland layer (B) submucosal gland layer to the bronchial wall (C) metaplastic mucos to the bronchial wall (D) cartilage to the submucosal gland layer

submucosal gland layer to the mucosal wall (TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 489

112

Gross examination of lungs that show airways that can be followed almost to the pleural surfaces is characteristic of (A) emphysema (B) bronchiectasis (C) pulmonary sequestration (D) chronic bronchitis

Bronchiectasis(TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 493

113

Usual interstitial pneumonia, or idiopathic pulmonary fibrosis, is differentiated from other fibrosing interstitial diseases by (A) the temporal heterogeneity of the fibrosing lesions (B) presence of a lymphocytic infiltrate (C) exuberant fibroblastic proliferation (D) association with a connective tissue disease such as SLE

the temporal heterogeneity of the fibrosing lesions (B is nonspecific and may occur in any; C may be seen in cryptogenic organizing pneumonia; D is wrong because by definition, "idiopathic" must not be associated with other conditions) (TOPNOTCH)Robbins Basic Pathology, 8th Ed. Pp. 495-496

114

Which cell is the key element in the initiation and perpetuation of lung injury and fibrosis in pneumoconioses? (A) alveolar macrophage (B) neutrophil (C) respiratory epithelium basal cell (D) type II pneumocyte

alveolar macrophage (TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 497

115

Which pneomoconiosis is associated with an increased susceptibility to tuberculosis? (A) anthracosis (B) silicosis (C) asbestosis (D) sarcoidosis

silicosis (TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 499

116

Concomitant cigarette smoking in patients who have been exposed to asbestos greatly increases the risk of (A) bronchogenic carcinoma (B) mesothelioma (C) carcinoid tumor (D) hamartoma

bronchogenic carcinoma (TOPNOTCH)Robbins Basic Pathology, 8th Ed. p. 500, 530

117

Which of the following is more prevalent in nonsmokers than smokers? (A) sarcoidosis (B) centriacinar emphysema (C) desquamative interstitial pneumonia (D) respiratory bronchiolitis

sarcoidosis (TOPNOTCH)Robbins Basic Pathology, 8th Ed. P. 501

118

What is the histopathologic sine qua non of sarcoidosis? (A) noncaseating epithelioid granuloma (B) Schaumann bodies (C) asteroid bodies (D) caseation necrosis

noncaseating epithelioid granuloma (TOPNOTCH)Robbins Basic Pathology, 8th Ed. P501

119

A 33 year old woman with mitral stenosis from rheumatic heart disease develops hepatomegaly and bipedal edema. She eventually dies of heart failure. An autopsy is done. Which of the following lung findings supports pulmonary hypertension? (A) coagulative necrosis of alveoli with intraparenchymal hemorrhage (B) medial hypertrophy and reduplication of elastic membranes in small arteries (C) medium arteries with chronic inflammatory infiltrate and fibrinoid necrosis (D) vessels of varying caliber with endothelial proliferation

medial hypertrophy and reduplication of elastic membranes in small arteries (TOPNOTCH)Robbins Basic Pathology, 8th Ed. P 507

120

A 40 year old lady develops progressive dyspnea and hemoptysis of 1 week. On further history, she reports tea-colored urine. Her condition worsens, and she dies. At autopsy, her lung alveoli have thickened fibrous septa, and the lumens diffusely filled with hemosiderin-laden macrophages. Immunofluorescence showed a linear pattern of immunoglobulin deposition along the alveolar septa. Kidney samples also showed the same pattern. Her dismal clinical picture is a consequence of antibodies against (A) fibrillin (B) elastin (C) collagen III (D) collagen IV

collagen IV (Goodpasture syndrome) (TOPNOTCH)Robbins Basic Pathology, 8th Ed. Pp 507-508