XIX - Female Genital System and the Breast Flashcards Preview

Pathology > XIX - Female Genital System and the Breast > Flashcards

Flashcards in XIX - Female Genital System and the Breast Deck (151)
Loading flashcards...
31

Microscopically, the distinguishing feature is a variety of immature or barely recognizable areas of differentiation toward cartilage, bone, muscle, nerve, and other structures. Found early in life.

Immature Malignant Teratomas (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 733

32

Tumor of the ovary composed entirely of mature thyroid tissue. May hyperfunction and produce hyperthyroidism. Appear as small, solid, unilateral brown ovarian masses

Struma ovarii (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 733

33

A voluminous mass of swollen, sometimes cystically dilated, chorionic villi, appearing grossly as grapelike structures.

Hydatidiform Mole (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 735

34

This type of H. mole shows hydropic swelling of chorionic villi and virtual absence of vascularization of villi. No fetal parts seen.

Complete mole (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 736

35

This type of H. mole shows villous edema that involves only some of the villi and the trophoblastic proliferation is focal and slight, with characteristic irregular scalloped margin. Fetal parts/embryo may be seen.

Partial mole(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 736

36

These are complete moles that are more invasive locally but do not metastasize. Microscopically, the epithelium of the villi is marked by hyperplastic and atypical changes, with proliferation of both cuboidal and syncytial components.

Invasive Mole (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 736

37

Appear as very hemorrhagic, necrotic masses within the uterus. The tumor is purely epithelial, composed of anaplastic cuboidal cytotrophoblast and syncytiotrophoblast, chorionic villi are not formed. High propensity for metastasis.

Choriocarcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 737

38

A cystic dilation of an obstructed duct that arises during lactation.

Galactocele (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 739

39

Multifocal, bilateral blue-brown cysts ("blue dome cysts") of the breast, measuring 1-5 cm diameter, filled with serous turbid fluid. Occurs normally in the menstrual cycle.

Simple fibrocystic change of the breast(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 739

40

Term used to describe hyperplasia that cytologically resemble lobular carcinoma in situ, but the cells do not fill or distend more than 50% of the acini within a lobule.

Atypical lobular hyperplasia (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 739

41

The lumen of the ducts, ductules, or lobules of the breast is filled with a heterogeneous population of cells of different morphologies. Irregular slit-like fenestrations are prominent at the periphery.

Epithelial Hyperplasia (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 739

42

These lesions are characterized by proliferation of lining epithelial cells and myoepithelial cells in small ducts and ductules, yielding masses of small gland patterns within a fibrous stroma. The acini are arranged in a swirling pattern, and the outer border is usually well circumscribed.

Sclerosing Adenosis (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 741

43

A nonbacterial chronic inflammation of the breast associated with inspissation of breast secretions in the main excretory ducts.

Mammary duct ectasia (periductal or plasma cell mastitis) (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 742

44

The lesion is small, often tender, rarely more than 2 cm in diameter, and sharply localized, with a central focus of necrotic fat cells surrounded by neutrophils and lipid-filled macrophages. Caused by some antecedent trauma to the breast.

Traumatic fat necrosis (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 742

45

The most common benign neoplasm of the female breast.

Fibroadenoma(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 742

46

A discrete, usually solitary, freely movable nodule, 1 to 10 cm in diameter, easily "shelled out" lesion of the breast. Histologically there is a loose fibroblastic stroma containing ductlike, spaces lined by a layer of epithelium that are regular and have a well-defined, intact basement membrane.

Fibroadenoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 742

47

Small lobulated and cystic lesion of the breast that may grow rapidly. Exhibit "leaflike" clefts and slits on gross section.

Phyllodes Tumor (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 743

48

A neoplastic papillary growth within a duct, usually solitary and less than 1 cm in diameter, consisting of delicate, branching growths within a dilated duct or cyst.

Intraductal Papilloma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 743

49

A type of noninvasive carcinoma of the breast that tends to fill, distort, and unfold involved lobules and thus appears to involve ductlike spaces.

Ductal Carcinoma in Situ(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 745

50

A type of noninvasive carcinoma of the breast expands but does not alter the underlying lobular architecture. cells are monomorphic with bland, round nuclei and occur in loosely cohesive clusters in ducts and lobules. Tend to be bilateral, and increases risk for development of breast CA.

Lobar Carcinoma in Situ(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 746

51

Caused by the extension of DCIS up to the lactiferous ducts and into the contiguous skin of the nipple.

Paget disease of the nipple (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 746

52

This type of cancer produces a desmoplastic response, replacing normal breast fat and forms a hard, palpable mass. Advanced cancers may cause dimpling of the skin, retraction of the nipple, or fixation to the chest wall.

Invasive ductal carcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 747

53

Breast cancer defined by the clinical presentation of an enlarged, swollen, erythematous breast, usually without a palpable mass. The blockage of numerous dermal lymphatic spaces by carcinoma results in the clinical appearance (e.g peau d' orange)

Inflammatory carcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 747

54

Breast cancer which consists of cells morphologically identical to the cells of LCIS. Occasionally they surround cancerous or normal-appearing acini or ducts, creating a so-called "bull's-eye pattern."

Invasive lobular carcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 747

55

A rare subtype of carcinoma consisting of sheets of large anaplastic cells with pushing, well-circumscribed borders, with a pronounced lymphoplasmacytic infiltrate.

Medullary carcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 747

56

A rare subtype of carcinoma which appear grossly as a soft and gelatinous mass which abundant quantities of extracellular mucin that dissects into the surrounding stroma.

Colloid (mucinous) carcinoma (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 747

57

Usually present as irregular mammographic densities. Microscopically, the carcinomas consist of well-formed tubules with low-grade nuclei. Lymph node metastases are rare, and prognosis is excellent.

Tubular carcinomas (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 747

58

Grossly, appears as a button-like, subareolar swelling. in bilateral breasts of males.

Gynecomastia (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 750

59

Large, multilocular tumors of the ovaries, without psammoma bodies. Composed of mucin-producing epithelial cells.

Mucinous Tumors (TOPNOTCH) Robbins Basic Pathology, 8th ed., p 731

60

Metastasis of mucinous tumor of the gastrointestinal tract to the ovaries is called?

Krukenberg tumor(TOPNOTCH) Robbins Basic Pathology, 8th ed., p 731