XVI - The Liver, Gallbladder and Biliary Tree Flashcards Preview

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Flashcards in XVI - The Liver, Gallbladder and Biliary Tree Deck (153)
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91

What do you call the small tubular channels that are sometimes burried within the gallbladder wall adjacent to the liver?

Ducts of Luschka(TOPNOTCH)

92

What is the most common congenital anomaly seen in the Gallbladder?

A folded fundus or so called phrygian cap(TOPNOTCH)

93

Gross morphology: the mucosal surface of the gallbladder is studded with minute yellow flecks

Strawberry Gallbladder(TOPNOTCH)

94

What type of pigment stones are generally seen in infected intrahepatic or extra hepatic ducts?

Brown pigment stones(TOPNOTCH)

95

Gross morphology: GB is shrunken, nodular, and chronically inflamed with foci of necrosis and hemorrhage

Xanthogranulomatous cholecystitis(TOPNOTCH)

96

Hallmarks of HCV infection

Persistent infection and chronic hepatitis (TOPNOTCH) Robbins Pathologic Basis of Disease, 9th ed., p. 834

97

Defining histologic feature of chronic viral hepatitis

Mononuclear portal infiltration (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 837

98

Diagnostic hallmark of Hepatitis B; these are cells with ER swollen by HBsAg

Ground-glass hepatocytes(TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 837

99

Characteristic feature of alcoholic hepatitis which present as clumped, amorphous, eosinophilic material in ballooned hepatocytes. May also be present in Wilson disease and in chronic biliary tract disease.

Mallory-Denk bodies (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 843

100

Deeply eosinophilic staining apoptotic hepatocytes seen in acute and chronic hepatitis.

Acidophilic bodies (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 823

101

The principal cell type involve in scar deposition in the liver

Hepatic stellate cell(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 823

102

Associated with encephalopathy and coagulopathy that occurs within 26 weeks of initial liver injury in the absence of pre-existing liver disease, caused by massive hepatic necrosis

Acute liver failure(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 825

103

Most common intrahepatic cause of portal hypertension

Cirrhosis(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 828

104

Most frequent mode of transmission of HBV in high prevalence regions

Transmission during childbirth(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 832

105

Most frequent mode of transmission of HBV in low prevalence regions

Unprotected sex and IV drug abuse(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 832

106

Serologic marker detected during window period of HBV infection

IgM anti-HBc antibody(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 833

107

Best predictor of chronicity of HBV infection

Age at the time of infection(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 833

108

Most common risk factor for HCV infection

IV drug abuse(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 834

109

Type of viral hepatitis associated with metabolic syndrome

Hepatitis C virus infection (TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 835

110

Type of viral hepatitis implicated in the high mortality rate among pregnant women

Hepatitis E Virus infection(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 835

111

Main inflammatory cells in both acute and chronic viral hepatitis

T cells(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 839

112

Type of autoimmune hepatitis most often seen in middle-aged women and is most characteristically associated with antinuclear and anti-smooth muscle antibodies

Type 1 autoimmune hepatitis(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 840

113

Type of autoimmune hepatitis most often seen in children or teenager and is associated with anti-liver kidney microsomal autoantibodies

Type 2 autoimmune hepatitis(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 840

114

Predominant cells and characteristic component of inflammatory infiltrate in biopsy specimens showing autoimmune hepatitis

Plasma cells(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 840

115

Most common hepatotoxin causing acute liver failure

Acetaminophen(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 841

116

Most common hepatotoxin causing chronic liver disease

Alcohol(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 841

117

Characterized by hepatocyte swelling and necrosis, Mallory-Denk bodies, neutrophilic reaction, fibrosis, perisinosoidal scar in the space of Disse of the centrilobilar region

Alcohol Hepatitis(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 843

118

Micronodular cirrhosis described for end-stage alcoholic liver disease due o long-term alochol use

Laennec cirrhosis(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 843

119

Volume threshold for the developmet of alcoholic liver disease

80gm/day of alcohol(TOPNOTCH)Robbins Basic Pathology, 9th ed. P. 845

120

Most common site of hemosiderin deposition

Liver(TOPNOTCH)Robbins Basic Pathology, 9th ed., p. 848