0.9% Sodium Chloride (Normal Saline)

Question 1

Generic/Trade Name

0.9% Sodium Chloride

Answer 1

Normal Saline

Question 2

Generic/Trade Name

Normal Saline

Answer 2

0.9% Sodium Chloride

Question 3

0.9% Sodium Chloride (Normal Saline)

Classification:

Answer 3

• Isotonic crystalloid solution

Question 4

0.9% Sodium Chloride (Normal Saline)

Mechanism of Action

Answer 4

• Volume replacement
• Water and electrolytes

Question 5

0.9% Sodium Chloride (Normal Saline)

Onset of Action

Answer 5

Immediate

Question 6

0.9% Sodium Chloride (Normal Saline)

Peak Effects

Answer 6

• Immediate

Question 7

0.9% Sodium Chloride (Normal Saline)

Duration of Effect

Answer 7

Varies by disease process or until renal clearance

Question 8

0.9% Sodium Chloride (Normal Saline)

Half-Life

Answer 8

Not Applicable

Question 9

0.9% Sodium Chloride (Normal Saline)

Indications/Field Use:

Answer 9

• Dehydration secondary to heat-related emergency
• Shock/Hypotension/Hypovolemia
• Diabetic Ketoacidosis
• Keep open IV

Question 10

0.9% Sodium Chloride (Normal Saline)

Contraindications:

Answer 10

• Pulmonary edema
• Severe Hypertension

Question 11

0.9% Sodium Chloride (Normal Saline)

Side Effects/Adverse Reactions:

Answer 11

• May induce pulmonary edema if given to patient with history of CHF

Question 12

0.9% Sodium Chloride (Normal Saline)

ADULT Dose:

Answer 12

• 200-250cc IV, IO,
• repeat until BPSystolic>100,
• max dose 2000cc

Question 13

0.9% Sodium Chloride (Normal Saline)

PEDI Dose:

Answer 13

• (PEDI): 20cc/kg IV, IO for > 1mos;
• 10cc/kg for
• Cardiogenic Shock (PEDI) 5-10cc/kg IV, IO

Question 14

0.9% Sodium Chloride (Normal Saline)

Precautions:

Answer 14

• May cause depletion of other electrolytes when administered in large volumes
• May dilute oxygen carrying capacity in patient with severe bleeding
• If hypotension persists after 2000cc, consider α1 agonist infusion (i.e. Dopamine)