10- Blood Coagulation - Incomplete (Final)

Question 1

Define Hemostasis

Answer 1

process of stopping blood loss

Question 2

Define Blood coagulation

Answer 2

principle mechanism of hemostasis

Question 3

Define Blood clot

Answer 3

mesh of protein filaments that traps blood’s formed elements to
form a red, gelatinous mas

Question 4

Define Fibrin threads

Answer 4

threads that holds the blood cells together and they seal the
wound to prevent loosing of blood

Question 5

Clotting factors are Present in the blood at all times in their (Active/Inactive) form

Answer 5

Inactive

Question 6

Clotting factors are activated through which pathways?

Answer 6

extrinsic and intrinsic pathways

Question 7

Clotting factors are produced by the

Answer 7

liver

Question 8

______ is required to produce Clotting factors

Answer 8

Vitamin K

Question 9

CF I AKA

Answer 9

Fibrinogen

Question 10

CF II AKA

Answer 10

Prothrombin

Question 11

CF V AKA

Answer 11

Preaccelerin

Question 12

CF VII AKA

Answer 12

Proconvertin

Question 13

CF VIII AKA

Answer 13

Antihemophilic factor

Question 14

CF IX AKA

Answer 14

Christmas factor

Question 15

CF X AKA

Answer 15

Stuart-Prower factor

Question 16

CF XI AKA

Answer 16

Plasma thromboplastin antecedent

Question 17

CF XII AKA

Answer 17

Hageman factor

Question 18

CF XIII AKA

Answer 18

Fibrin-stabilizing factor

Question 19

Coagulation results from fibrin and fibrin result of

Answer 19

fibrinogen.

Question 20

Fibrinogen is normally inactive and gets activated by

Answer 20

thrombi

Question 21

thrombi result from

Answer 21

prothrombin from clotting factor X(stuart-power factor)

Question 22

Extrinsic Pathway happens to cells that are damaged within

(Location of the damage)

Answer 22

within blood vessels and outside of the vessels

Question 23

Tissue factor (aka Tissue Thromboplastin) – released by

Answer 23

injured cells, both injured blood vessel cells and injured tissue cell

Question 24

Tissue factor (aka Tissue Thromboplastin) activates

Answer 24

clotting factor 7- proconvertin

Question 25

Proconvertin (CF 7) activates

Answer 25

Stuart-Prower factor (CF 10)

Question 26

What triggers Intrinsic Pathway

Answer 26

Exposure of collagen fibers of subendothelial cells of blood vessels

(Only inside the injured vessels)

Question 27

Collagen fibers exposed leads to activation of _____ which ends up in activating _____

Answer 27

Collagen fibers exposed > Hageman factor (CF 12) > > > Stuart-Prower factor (CF 10)