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3B2 Aantekeningen > (10) HC.5 Monoamines en depressie > Flashcards

(10) HC.5 Monoamines en depressie Flashcards

1
Q

Werking antidepressiva

A

Remming heropame (dopamine, serotonine) ->
Minder signaal en verzadiging receptoren v. projecterende neuron ->
Gevolg is desentizering ->
Geen remming signaal meer ->
Hoger signaal, dus “blijer”

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2
Q

5-HT =

A

= serotonine

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3
Q

Klassieke antidepressiva (TCA)

A
  • Amytriptiline
  • nortriptiline
  • inipramine
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4
Q

Selectieve Serotonine Re-uptake Inhibitors (SSRI)

A
  • Paraxetine
  • Citalopram
  • fluoxetine
  • fluvoxamine
  • sertraline
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5
Q

Serotonine Noradrenaline Re-uptake Inhibitors (SNRI)

A
  • Venlafaxine
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6
Q

Alfa2 receptor antagonisten

A
  • Mianserine
  • Mitrazepine
  • Trazadon
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7
Q

MAO-A remmers

A
  • Tranylcypromine
  • Moclobemide
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8
Q

Volgorde antidepressiva

A

1 - SSRI
2 - SNRI
3 - Klassieke antidepressiva
4 - MAO-A remmers

Bij psychotische of melancholische kenmerken TCA eerst, dan SNRI als nodig

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3B2 Aantekeningen (22 decks)

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