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3B2 Aantekeningen > (13) HC.3 Opioïden en andere analgetica > Flashcards

(13) HC.3 Opioïden en andere analgetica Flashcards

1
Q

Paracetamol werkt via

A

COX inhibitie

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2
Q

Opiaat =
Opioïd =

A

Opiaat = stof met morfine-achtige werking
Opioïd = stof met morfine-achtige eigenschappen

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3
Q

Opioïd-receptoren
- soort receptoren
- werking

A

G-eiwit gekoppeld, soorten:
- Mu (MOPr), Delta (DOPr), Kappa (KOPr)
- Verlaging cAMP -> K-kanalen hyperpolariseren (open), dus remming neurale excitabiliteit + sluiting Ca-kanalen, dus remming transmitter release

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4
Q

Migraine behandeling

A

Paracetamol of NSAID, geen opioïd

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3B2 Aantekeningen (22 decks)

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