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3B2 Aantekeningen > (12) HC.2 Farmacologie van verslaving > Flashcards

(12) HC.2 Farmacologie van verslaving Flashcards

1
Q

Amfetamine werking

A

Re-uptake blokkeren -> dus hogere spiegels

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2
Q

Abstinentie syndroom

A

lichaam balanceert drug uit (tolerantie fenomeen) dmv bv nieuwe receptoren -> abstinentie brengt dit weer uit balans in omgekeerde reactie

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3
Q

Neurotransmitters betrokken bij craving

A

GABA, Dopamine, Endogene Opioïden

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4
Q

Fysiologie verslaving

A

Drug (bv morfine) -> remt GABA -> GABA remt normaal de impuls naar n. accumbens -> nu dus verhoogd

Drug kan ook de concentratie in synapsspleet verhogen

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5
Q

Overdosis komt binnen, wat geef je

A

Nalaxon

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3B2 Aantekeningen (22 decks)

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