Rheumatology basics Flashcards

1
Q

Arthropathy

A

disease of the joint

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2
Q

Arthritis

A

inflammation of the joint

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3
Q

Arthralgia

A

pain in a joint

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4
Q

What causes loss of regulation of antibody production?

A

multifactorial
- genetic predisposition
- environmental insults:
- infection and prolonged chemical exposure

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5
Q

what type of arthritis have autoantibodies involved?

A

seropositive

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6
Q

what are the seropositive arthritic conditions?

A
Rheumatoid Arthritis 
SLE
Sjogren's 
Systemic sclerosis (limited) 
Systemic sclerosis (diffuse) 
Mixed Connective Tissue Disease 
All liver disease 
Small cell vasculitis 
Myositis 
Anti-phospholipid syndrome
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7
Q

what seropositive antibodies are involved in rheumatoid arthritis?

A

Anti-CCP

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8
Q

what seropositive antibodies are involved in SLE?

A
ANA
Anti-dsDNA 
Anti-Sm 
Anti-Ro
Anti-RNP
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9
Q

what seropositive antibodies are involved in Sjorgen’s?

A

ANA
Anti-Ro
Anti-La

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10
Q

what seropositive antibodies are involved in Systemic sclerosis (limited)?

A

ANA

Anti-centromere

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11
Q

what seropositive antibodies are involved in Systemic sclerosis (diffuse)?

A

ANA

Anti-Scl-70

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12
Q

what seropositive antibodies are involved in MCTD?

A

ANA

Anti-RNP

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13
Q

what seropositive antibodies are involved in all liver disease?

A

ANA

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14
Q

what seropositive antibodies are involved in small cell vasculitis?

A

ANCA

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15
Q

what seropositive antibodies are involved in myositis?

A

Anti-jo1

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16
Q

what seropositive antibodies are involved in anti-phospholipid syndrome?

A

anti-cardiolipin and lupus anticoagulant