Ischemic Heart Disease

Question 1

Treatment Approach for Stable Ischemic Heart Disease

Answer 1

A - Antiplatelet and antianginal drugs (BB, CCB, Nitrates)

B - Blood Pressure and BB
C - Cholesterol (statins) and cigarettes (cessation)
D- Diet and diabetes
E- Exercise and education

Question 2

Aspirin brand names

Answer 2

Bayer, Bufferin, Ecotrin

Question 3

Plavix

Answer 3

Clopidogrel

Question 4

BB are 1st line for what

Answer 4

SIHD

Question 5

CCB are preferred for what

Answer 5

Prinzmetal’s angina

Question 6

Nitrostat

Answer 6

Nitroglycerin SL tablet

Question 7

Nitromist, Nitrolingual Pumpspray

Answer 7

Nitroglycerin translingual spray

Question 8

Nitroglycerin major DDI

Answer 8

PDE-5 inhib can cause drastic decrease in BP

Question 9

How to administer nitrate patch

Answer 9

12 on 12 off otherwise tolerance will build

Question 10

clopidogrel DDI

Answer 10

Prodrug: do not use with omeprazole or esomeprazole

Question 11

aspirin warnings

Answer 11

bleeding, titinus in overdose

Question 12

dual antiplatelet therapy length in stents and CABG

Answer 12

bare metal 1 month, drug eluting 6 months, post cabg 1 year

Question 13

mechanism of beta blocker effect

Answer 13

reduce heart rate, contractility, and left ventricular wall tension

Question 14

mechanism of ccb effect

Answer 14

non dhp: decrease hr and contractility

DHP: decrease SVR (afterload)

Question 15

Target HR for beta blockers

Answer 15

55 to 60 bpm

Question 16

which antianginal drug can cause QT prolongation?

Answer 16

Ranolazine

Question 17

Timing of SL nitroglycerin

Answer 17

Can give up to 3 doses at 5 minute intervals

Question 18

Storage of nitroglycerin

Answer 18

Only lasts 6 months, keep in the dark and dry

Question 19

all nitroglycerin side effects

Answer 19

headache, flushing, orthostasis