arrhythmias Flashcards

1
Q

nexterone

A

amiodarone (1/2)

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2
Q

pacerone

A

amiodarone (2/2)

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3
Q

half life of amiodarone

A

40-60 days

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4
Q

amiodarone contraindications

A

iodine hypersensitivity

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5
Q

amiodarone monitoring

A

pulmonary toxicity, hepatotoxicity

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6
Q

amiodarone structure

A

contains two iodine molecules which explains ddi with thyroid meds and iodine sensitivity warning

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7
Q

warnings of amiodstone

A

optic neuropathy, photosensitivity, neuropathy

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8
Q

diltiazem contraindications

A

heart failure

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9
Q

what class causes gingival hyperplasia

A

ccbs

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10
Q

therapeutic range for digoxin

A

afib: 0.8 to 2
hf: 0.5 to 0.9

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11
Q

digoxin antidote

A

digifab

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12
Q

signs of dig tox

A

blurred vision, green yellow halos

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13
Q

digoxin dose adjust

A

if crcl<50 or if switching from oral to iv lower dose by 20-25%

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14
Q

disopyramide side effects

A

anticholinergic

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15
Q

quinine administration

A

take with food

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16
Q

which antiarrhythmics can cause dile

A

procainimide, quinine (coombs)

mostly class 1a

17
Q

procainimide dosing

A

4-10 mcg/ml

18
Q

leaching issues with pvc pneumonic

A
Leach - lorazepam 
Absorbs - Amiodarone 
To - Tacrolimus
Take - Taxares
In - Insulin
Nutrients - Nitroglycerin
19
Q

what form does lidocaine come in and what is that used for?

A

refractory vt/cardiac arrest

20
Q

what kind of beta blocker is sotalol

A

non selective

21
Q

when do you reduce frequency of sotalol dose?

A

when crcl<60

22
Q

what form does ibulitide come in

A

iv

23
Q

which antiarrhythmic needs continous monitoring?

A

dofetilide - continous ecg and crcl for a min of 3 days

24
Q

what is the half life of adenosine

A

10 seconds

25
Q

what is adenosine used in?

A

paroxysmal supraventricular tachycardia

26
Q

flecainide is contraindicated in what

A

heart failure, MI

27
Q

pneumonic for antiarrhythmic classification

A

1a) double quarter pounder
1b) lettuce, mayo,
1c) fries please.
2) because
3) dieting during stress is always
4) very difficult.

28
Q

key drugs that prolong qt intervals

A
  • class i (esp 1a) and iii antiarrhythmics
  • antibiotics - quinolones and macrolides
  • antidepressants - TCAs, SSRI, SNRI
  • antimetic drugs - 5-HT3 receptor antagonists, dropinerol/phenothiazines
  • most antipsyxhotics
  • other: tacrolimus, donepezil, fingolimod, methadone
29
Q

paroxysmal afib

A

terminates spontaneously or with intervention within 7 days of onset

30
Q

persistent

A

lasts longer than 7 days

31
Q

long standing persistent

A

lasts longer than 12 months

32
Q

permenant afib

A

treatment choicd to stop trying to restore nsr

33
Q

valvular

A

requires warfarin anticoagulation, afib with moderate to severe mitral stenosis

34
Q

goal hr for symptomatic afib

A

less than 80

35
Q

path of conduction

A

SA –> AV –> bundle of HIS –> purkinje fibers

36
Q

what happens in phase 0

A

rapid ventricular depoloarizaion due to na influx

class 1 works here

37
Q

what happens in phase 2 of ap

A

ca in, k out

38
Q

what happens in phase 3 of ap

A

k out

class 3 works here